2B7F
Crystal structure of human T-cell leukemia virus protease, a novel target for anti-cancer design
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, E, G... (A, B, C, D, E...) | HTLV protease | polymer | 116 | 12566.6 | 6 | UniProt (P10274) Pfam (PF00077) UniProt (by SIFTS) (P03362) | Human T-lymphotropic virus 1 | |
| 2 | C, F, I (I, J, K) | (ACE)APQV(STA)VMHP peptide | polymer | 10 | 1062.3 | 3 | BIRD (PRD_000429) | ||
| 3 | J, K (A, C) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | L, M, N, O, P... (A, B, I, C, D...) | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 116 (UniProt: P10274)
| PDB | External Database | Details |
|---|---|---|
| Ile 40 | Leu 72 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 78586.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 189.9 | |
| All* | Total formula weight | 78776.3 |
