Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| E | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| F | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 201 |
| Chain | Residue |
| A | TYR114 |
| A | LEU115 |
| A | PRO116 |
| B | PRO1 |
| E | TYR114 |
| E | LEU115 |
| E | PRO116 |
| F | PRO1 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 C 202 |
| Chain | Residue |
| C | LEU115 |
| C | LEU115 |
| C | PRO116 |
| C | PRO116 |
| D | PRO1 |
| D | ARG81 |
| C | TYR114 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR CHAIN I OF (ACE)APQV(STA)VMHP PEPTIDE |
| Chain | Residue |
| A | ARG10 |
| A | ASP32 |
| A | GLY34 |
| A | ALA35 |
| A | ASP36 |
| A | MET37 |
| A | SER55 |
| A | VAL56 |
| A | LEU57 |
| A | GLN62 |
| A | TRP98 |
| B | ARG10 |
| B | ASP32 |
| B | GLY34 |
| B | ALA35 |
| B | ASP36 |
| B | SER55 |
| B | LEU57 |
| B | GLY58 |
| B | ALA59 |
| B | TRP98 |
| I | HOH1 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR CHAIN J OF (ACE)APQV(STA)VMHP PEPTIDE |
| Chain | Residue |
| C | ARG10 |
| C | ASP32 |
| C | GLY34 |
| C | ALA35 |
| C | ASP36 |
| C | SER55 |
| C | VAL56 |
| C | LEU57 |
| C | GLY58 |
| C | ALA59 |
| C | TRP98 |
| C | ILE100 |
| D | ARG10 |
| D | ASP32 |
| D | GLY34 |
| D | ALA35 |
| D | ASP36 |
| D | MET37 |
| D | SER55 |
| D | VAL56 |
| D | LEU57 |
| D | GLY58 |
| D | TRP98 |
| D | HOH117 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR CHAIN K OF (ACE)APQV(STA)VMHP PEPTIDE |
| Chain | Residue |
| E | ARG10 |
| E | ASP32 |
| E | GLY34 |
| E | ALA35 |
| E | ASP36 |
| E | MET37 |
| E | SER55 |
| E | LEU57 |
| E | GLN62 |
| E | TRP98 |
| F | ARG10 |
| F | ASP32 |
| F | GLY34 |
| F | ALA35 |
| F | ASP36 |
| F | SER55 |
| F | LEU57 |
| F | ALA59 |
| F | TRP98 |
| K | HOH3 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADMTVI |
| Chain | Residue | Details |
| A | ALA29-ILE40 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 468 |
| Details | Domain: {"description":"Peptidase A2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00275","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"description":"For protease activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU00275","evidenceCode":"ECO:0000255"}]} |
