1S8F
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2QCH
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2QCL
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2QCC
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2QCM
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2QCG
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2QCN
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2QCD
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2QCF
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2QCE
| Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to sulfate, glycerol, and chloride | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Wittmann, J, Rudolph, M. | 登録日 | 2007-06-19 | 公開日 | 2007-11-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
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3EWW
| D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-cyano-UMP, covalent adduct | 分子名称: | 6-[(E)-iminomethyl]uridine 5'-phosphate, GLYCEROL, Orotidine-5'-phosphate decarboxylase | 著者 | Heinrich, D, Wittmann, J, Diederichsen, U, Rudolph, M. | 登録日 | 2008-10-16 | 公開日 | 2009-04-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase Chemistry, 15, 2009
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3L0N
| Human orotidyl-5'-monophosphate decarboxylase in complex with 6-mercapto-UMP | 分子名称: | 6-sulfanyluridine-5'-phosphate, Uridine 5'-monophosphate synthase | 著者 | Heinrich, D, Wittmann, J, Diederichsen, U, Rudolph, M. | 登録日 | 2009-12-10 | 公開日 | 2010-01-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase Chemistry, 15, 2009
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3EWU
| D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-acetyl-UMP, covalent adduct | 分子名称: | 6-ethyluridine 5'-phosphate, GLYCEROL, Orotidine-5'-phosphate decarboxylase, ... | 著者 | Heinrich, D, Wittmann, J, Diederichsen, U, Rudolph, M. | 登録日 | 2008-10-16 | 公開日 | 2009-04-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase Chemistry, 15, 2009
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3EWX
| K314A mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-azido-UMP, degraded to BMP | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine-5'-phosphate decarboxylase | 著者 | Heinrich, D, Wittmann, J, Diederichsen, U, Rudolph, M. | 登録日 | 2008-10-16 | 公開日 | 2009-04-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase Chemistry, 15, 2009
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