PDB Search results for query - 日本蛋白質結構資料庫

PDB: 887 results

Crystal structure of VRC01c-HuGL2 Fab from an HIV-1 naive donor in complex with with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.16 A
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, ...
Authors:	Sarkar, A, Wilson, I.A.
Deposit date:	2016-02-25
Release date:	2016-04-06
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.16 Å)
Cite:	HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen. Science, 351, 2016

3IMS

Transthyretin in complex with 2,6-dibromo-4-(2,6-dichlorophenethyl)phenol
Descriptor:	2,6-dibromo-4-[2-(2,6-dichlorophenyl)ethyl]phenol, Transthyretin
Authors:	Connelly, S, Wilson, I.A.
Deposit date:	2009-08-11
Release date:	2010-01-12
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity. J.Am.Chem.Soc., 132, 2010

5IFA

Crystal structure of unbound VRC01c-HuGL2 Fab from an HIV-1 naive donor at 1.82 A
Descriptor:	GLYCEROL, PENTAETHYLENE GLYCOL, SULFATE ION, ...
Authors:	Sarkar, A, Wilson, I.A.
Deposit date:	2016-02-25
Release date:	2016-04-06
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.821 Å)
Cite:	HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen. Science, 351, 2016

3FO2

Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Gln mutant)
Descriptor:	5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera
Authors:	Debler, E.W, Wilson, I.A.
Deposit date:	2008-12-27
Release date:	2009-11-10
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.18 Å)
Cite:	An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket. Proc.Natl.Acad.Sci.USA, 106, 2009

3FO1

Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Ala mutant)
Descriptor:	5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera
Authors:	Debler, E.W, Wilson, I.A.
Deposit date:	2008-12-27
Release date:	2009-11-10
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket. Proc.Natl.Acad.Sci.USA, 106, 2009

5HZQ

Crystal structure of cellular retinoic acid binding protein 2 (CRABP2)-aryl fluorosulfate covalent conjugate
Descriptor:	4'-[(3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy][1,1'-biphenyl]-4-yl sulfurofluoridate, Cellular retinoic acid-binding protein 2, GLYCEROL
Authors:	Chen, W, Mortenson, D.E, Wilson, I.A, Kelly, J.W.
Deposit date:	2016-02-02
Release date:	2016-06-01
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue. J.Am.Chem.Soc., 138, 2016

3GMM

Structure of mouse CD1d in complex with C8Ph
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:	Schiefner, A, Wilson, I.A.
Deposit date:	2009-03-14
Release date:	2009-11-10
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009

3GMR

Structure of mouse CD1d in complex with C8Ph, different space group
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:	Schiefner, A, Wilson, I.A.
Deposit date:	2009-03-14
Release date:	2009-11-10
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009

3GMP

Structure of mouse CD1d in complex with PBS-25
Descriptor:	(2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Schiefner, A, Wilson, I.A.
Deposit date:	2009-03-14
Release date:	2009-11-10
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009

3GML

Structure of mouse CD1d in complex with C6Ph
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:	Schiefner, A, Wilson, I.A.
Deposit date:	2009-03-14
Release date:	2009-11-10
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009

3GMN

Structure of mouse CD1d in complex with C10Ph
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:	Schiefner, A, Wilson, I.A.
Deposit date:	2009-03-14
Release date:	2009-11-10
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009

3IMU

Transthyretin in complex with (E)-4-(3-aminostyryl)-2,6-dibromoaniline
Descriptor:	4-[(E)-2-(3-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
Authors:	Connelly, S, Wilson, I.A.
Deposit date:	2009-08-11
Release date:	2010-01-12
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity. J.Am.Chem.Soc., 132, 2010

3HJ0

Transthyretin in complex with a covalent small molecule kinetic stabilizer
Descriptor:	4-fluorophenyl 3-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoate, Transthyretin
Authors:	Connelly, S, Wilson, I.A, Kelly, J.W.
Deposit date:	2009-05-20
Release date:	2009-12-22
Last modified:	2014-11-19
Method:	X-RAY DIFFRACTION (1.34 Å)
Cite:	Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma. Nat.Chem.Biol., 6, 2010

3J5M

Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs
Descriptor:	BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ...
Authors:	Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B.
Deposit date:	2013-10-26
Release date:	2013-11-13
Last modified:	2018-07-18
Method:	ELECTRON MICROSCOPY (5.8 Å)
Cite:	Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science, 342, 2013

3IMV

Transthyretin in complex with (E)-4-(4-aminostyryl)-2,6-dibromoaniline
Descriptor:	4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
Authors:	Connelly, S, Wilson, I.A.
Deposit date:	2009-08-11
Release date:	2010-01-12
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.47 Å)
Cite:	A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity. J.Am.Chem.Soc., 132, 2010

2DBL

MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
Descriptor:	5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN)
Authors:	Arevalo, J.H, Wilson, I.A.
Deposit date:	1994-02-08
Release date:	1994-03-07
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Molecular basis of crossreactivity and the limits of antibody-antigen complementarity. Nature, 365, 1993

8TFR

Apo Fab from C10-S66K antibody
Descriptor:	Heavy chain from Fab of C10_S66K antibody, Immunoglobulin G-binding protein G, Light chain from Fab of C10_S66K antibody
Authors:	Pholcharee, T, Wilson, I.A.
Deposit date:	2023-07-11
Release date:	2023-08-16
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2.99 Å)
Cite:	An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. Acs Chem Neurosci, 14, 2023

8TFP

Fab from C10-S66K antibody in complex with carfentanil
Descriptor:	Carfentanil, Heavy chain of Fab from C10-S66K antibody, Light chain of Fab from C10-S66K antibody
Authors:	Pholcharee, T, Wilson, I.A.
Deposit date:	2023-07-11
Release date:	2023-08-16
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.78 Å)
Cite:	An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. Acs Chem Neurosci, 14, 2023

8TFQ

Fab from C10-S66K antibody in complex with fentanyl
Descriptor:	Heavy chain from Fab of C10_S66K antibody, Light chain from Fab of C10_S66K antibody, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
Authors:	Pholcharee, T, Wilson, I.A.
Deposit date:	2023-07-11
Release date:	2023-08-16
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. Acs Chem Neurosci, 14, 2023

1VAD

MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND YEAST ALPHA-GLUCOSIDASE
Descriptor:	BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, YEAST ALPHA-GLUCOSIDASE
Authors:	Fremont, D.H, Wilson, I.A.
Deposit date:	1994-11-01
Release date:	1996-06-20
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. Proc.Natl.Acad.Sci.USA, 92, 1995

8TXM

Crystal structure of 05.GC.w13.02 Fab in complex with H1 HA from A/California/04/2009(H1N1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_B, ...
Authors:	Lin, T.H, Moore, N, Wilson, I.A.
Deposit date:	2023-08-23
Release date:	2024-06-26
Method:	X-RAY DIFFRACTION (3.25 Å)
Cite:	Maturation of germinal center B cells after influenza vaccination in humans J.Exp.Med., 2024

8TXT

Crystal structure of 05.GC.w13.02 Fab in complex with H5 HA from A/Viet Nam/1203/2004(H5N1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_W13B_B, ...
Authors:	Lin, T.H, Moore, N, Wilson, I.A.
Deposit date:	2023-08-24
Release date:	2024-06-26
Method:	X-RAY DIFFRACTION (3.19 Å)
Cite:	Maturation of germinal center B cells after influenza vaccination in humans J.Exp.Med., 2024

8TY7

Crystal structure of 05.GC.w2.3C10 Fab in complex with H1 HA from A/California/04/2009(H1N1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w2_3C10, heavy chain, ...
Authors:	Lin, T.H, Moore, N, Wilson, I.A.
Deposit date:	2023-08-24
Release date:	2024-06-26
Method:	X-RAY DIFFRACTION (3.21 Å)
Cite:	Maturation of germinal center B cells after influenza vaccination in humans J.Exp.Med., 2024

8U44

CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06
Descriptor:	05.GC.w2.3C10-H1_SI06 Heavy chain, 05.GC.w2.3C10-H1_SI06 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Moore, N, Han, J, Ward, A.B, Wilson, I.A.
Deposit date:	2023-09-08
Release date:	2024-06-26
Method:	ELECTRON MICROSCOPY (3.41 Å)
Cite:	Persistence of germinal center B cell responses after influenza virus vaccination in humans To Be Published

3P3T

Human transthyretin (TTR) complexed with 4-(3-(2-flourophenoxy)propyl)-3,5-dimethyl-1H-pyrazole
Descriptor:	4-[3-(2-fluorophenoxy)propyl]-3,5-dimethyl-1H-pyrazole, Transthyretin
Authors:	Connelly, S, Wilson, I.A.
Deposit date:	2010-10-05
Release date:	2011-08-24
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.45 Å)
Cite:	Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity. Sci Transl Med, 3, 2011

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Total results:	887
Displayed results:	25
Sorted by:	Hit score (from highest)
Deposition authors:	"Wilson, I.A."