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PDB: 220 件

5TIM
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REFINED 1.83 ANGSTROMS STRUCTURE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE, CRYSTALLIZED IN THE PRESENCE OF 2.4 M-AMMONIUM SULPHATE. A COMPARISON WITH THE STRUCTURE OF THE TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE-GLYCEROL-3-PHOSPHATE COMPLEX
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, SULFATE ION, TRIOSEPHOSPHATE ISOMERASE
著者Wierenga, R.K, Hol, W.G.J.
登録日1991-04-23
公開日1992-10-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Refined 1.83 A structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 M-ammonium sulphate. A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3-phosphate complex.
J.Mol.Biol., 220, 1991
3TIM
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THE CRYSTAL STRUCTURE OF THE "OPEN" AND THE "CLOSED" CONFORMATION OF THE FLEXIBLE LOOP OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE
分子名称: TRIOSEPHOSPHATE ISOMERASE
著者Wierenga, R.K.
登録日1990-05-15
公開日1991-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of the "open" and the "closed" conformation of the flexible loop of trypanosomal triosephosphate isomerase.
Proteins, 10, 1991
6HSJ
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Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1) in complex with CoA
分子名称: ACETATE ION, COENZYME A, GLYCEROL, ...
著者Wierenga, R.K, Kiema, T.R, Thapa, C.J.
登録日2018-10-01
公開日2019-01-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
Biochem. J., 476, 2019
6HRV
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Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1)
分子名称: ACETATE ION, GLYCEROL, SCP2-thiolase (type-1)
著者Wierenga, R.K, Kiema, T.R, Thapa, C.J.
登録日2018-09-28
公開日2019-01-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
Biochem. J., 476, 2019
6HSP
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Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1) in complex with CoA and octanoyl-CoA
分子名称: COENZYME A, GLYCEROL, OCTANOYL-COENZYME A, ...
著者Wierenga, R.K, Kiema, T.R, Thapa, C.J.
登録日2018-10-01
公開日2019-01-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
Biochem. J., 476, 2019
6Z5F
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CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH 3-KETODECANOYL-COA AND OXIDISED NICOTINAMIDE ADENINE DINUCLEOTIDE
分子名称: 3-KETO-DECANOYL-COA, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Wierenga, R.K, Sridhar, S, Kiema, T.R.
登録日2020-05-26
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites.
Acta Crystallogr D Struct Biol, 76, 2020
6ZIB
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CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH ACETOACETYL-COA AND NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ACETOACETYL-COENZYME A, Peroxisomal bifunctional enzyme, ...
著者Wierenga, R.K, Sridhar, S, Kiema, T.R.
登録日2020-06-25
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH ACETOACETYL-COA AND NADH
To Be Published
6ZIC
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CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH 3S-HYDROXYBUTANOYL-COA AND NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-HYDROXYBUTANOYL-COENZYME A, GLYCEROL, ...
著者Wierenga, R.K, Sridhar, S, Kiema, T.R.
登録日2020-06-25
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH 3S-HYDROXYBUTANOYL-COA AND NADH
To Be Published
6Z5V
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CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH 3-KETODECANOYL-COA IN CROTONASE FOLD AND OXIDISED NICOTINAMIDE ADENINE DINUCLEOTIDE IN HAD FOLD
分子名称: 3-KETO-DECANOYL-COA, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Wierenga, R.K, Sridhar, S, Kiema, T.R.
登録日2020-05-27
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites.
Acta Crystallogr D Struct Biol, 76, 2020
6Z5O
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CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH COENZYME-A AND OXIDISED NICOTINAMIDE ADENINE DINUCLEOTIDE
分子名称: COENZYME A, GLYCEROL, NICOTINAMIDE, ...
著者Wierenga, R.K, Sridhar, S, Kiema, T.R.
登録日2020-05-27
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites.
Acta Crystallogr D Struct Biol, 76, 2020
1DUB
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BU of 1dub by Molmil
2-ENOYL-COA HYDRATASE, DATA COLLECTED AT 100 K, PH 6.5
分子名称: 2-ENOYL-COA HYDRATASE, ACETOACETYL-COENZYME A
著者Wierenga, R.K, Engel, C.K.
登録日1996-06-10
公開日1997-07-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of enoyl-coenzyme A (CoA) hydratase at 2.5 angstroms resolution: a spiral fold defines the CoA-binding pocket.
EMBO J., 15, 1996
1TRI
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BU of 1tri by Molmil
THE CRYSTAL STRUCTURE OF AN ENGINEERED MONOMERIC TRIOSEPHOSPHATE ISOMERASE, MONOTIM: THE CORRECT MODELLING OF AN EIGHT-RESIDUE LOOP
分子名称: SULFATE ION, TRIOSEPHOSPHATE ISOMERASE
著者Wierenga, R.K.
登録日1993-10-08
公開日1994-07-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of an engineered monomeric triosephosphate isomerase, monoTIM: the correct modelling of an eight-residue loop.
Structure, 1, 1993
6TIM
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THE ADAPTABILITY OF THE ACTIVE SITE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE AS OBSERVED IN THE CRYSTAL STRUCTURES OF THREE DIFFERENT COMPLEXES
分子名称: SN-GLYCEROL-3-PHOSPHATE, TRIOSEPHOSPHATE ISOMERASE
著者Noble, M.E.M, Wierenga, R.K, Hol, W.G.J.
登録日1991-04-23
公開日1992-10-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Proteins, 10, 1991
7ZSC
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Crystal structure of the heterodimeric human C-P4H-II with truncated alpha subunit (C-P4H-II delta281)
分子名称: Prolyl 4-hydroxylase subunit alpha-2, Protein disulfide-isomerase, SULFATE ION
著者Lebedev, A, Koski, M.K, Wierenga, R.K, Murthy, A.V, Sulu, R.
登録日2022-05-06
公開日2022-11-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H alpha 2 beta 2 tetramer.
J.Biol.Chem., 298, 2022
4EGV
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BU of 4egv by Molmil
Crystal structure of a monomeric SCP2-thiolase like protein type 1 (STLP1) from Mycobacterium smegmatis
分子名称: Acetyl-CoA acetyltransferase
著者Janardan, N, Harijan, R.K, Wierenga, R.K, Murthy, M.R.N.
登録日2012-04-01
公開日2012-09-12
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal Structure of a Monomeric Thiolase-Like Protein Type 1 (TLP1) from Mycobacterium smegmatis.
Plos One, 7, 2012
5LOT
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Crystal structure of SCP2 thiolase from Leishmania mexicana. Complex of the C123A mutant with acetyl-CoA.
分子名称: 3-ketoacyl-CoA thiolase-like protein, ACETYL COENZYME *A
著者Harijan, R.K, Kiema, T.-R, Wierenga, R.K.
登録日2016-08-09
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1.
Protein Eng. Des. Sel., 30, 2017
5LNQ
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Crystal structure of SCP2 thiolase from Leishmania mexicana. Complex of the C123A mutant with acetoacetyl-CoA.
分子名称: 3-ketoacyl-CoA thiolase-like protein, ACETOACETYL-COENZYME A
著者Harijan, R.K, Kiema, T.-R, Wierenga, R.K.
登録日2016-08-06
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1.
Protein Eng. Des. Sel., 30, 2017
1QDS
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BU of 1qds by Molmil
SUPERSTABLE E65Q MUTANT OF LEISHMANIA MEXICANA TRIOSEPHOSPHATE ISOMERASE (TIM)
分子名称: 2-PHOSPHOGLYCOLIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Lambeir, A.M, Backmann, J, Ruiz-Sanz, J, Filimonov, V, Nielsen, J.E, Vriend, G, Kursula, I, Norledge, B.V, Wierenga, R.K.
登録日1999-07-10
公開日2000-12-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase.
Eur.J.Biochem., 267, 2000
5OMO
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CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH WITH 3S-HYDROXY-DECANOYL-COA AND 3-KETO-DECANOYL-COA
分子名称: (S)-3-HYDROXYDECANOYL-COA, 3-KETO-DECANOYL-COA, GLYCEROL, ...
著者Kasaragod, P, Kiema, T.-R, Schmitz, W, Hiltunen, J.K, Wierenga, R.K.
登録日2017-08-01
公開日2017-09-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 1 (RPMFE1) COMPLEXED WITH 3S-HYDROXY-DECANOYL-COA AND 3- KETO-DECANOYL-COA
Not Published
4TIM
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CRYSTALLOGRAPHIC AND MOLECULAR MODELING STUDIES ON TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE: A CRITICAL ASSESSMENT OF THE PREDICTED AND OBSERVED STRUCTURES OF THE COMPLEX WITH 2-PHOSPHOGLYCERATE
分子名称: 2-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Nobel, M.E.M, Wierenga, R.K, Hol, W.G.J.
登録日1991-04-11
公開日1992-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallographic and molecular modeling studies on trypanosomal triosephosphate isomerase: a critical assessment of the predicted and observed structures of the complex with 2-phosphoglycerate.
J.Med.Chem., 34, 1991
7QLG
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CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT L259V COMPLEXED WITH FE, NADH, AND GLYCEROL
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FE (III) ION, GLYCEROL, ...
著者Sridhar, S, Kiema, T.R, Widertsen, M, Wierenga, R.K.
登録日2021-12-20
公開日2022-12-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity.
Iucrj, 10, 2023
7QLS
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CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT N151G, L259V COMPLEXED WITH FE, NADH, AND DIMETHOXYPHENYL ACETAMIDE
分子名称: 2-(3,4-dimethoxyphenyl)ethanamide, ADENOSINE-5-DIPHOSPHORIBOSE, FE (III) ION, ...
著者Sridhar, S, Kiema, T.R, Wierenga, R.K, Widersten, M.
登録日2021-12-20
公開日2022-12-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity.
Iucrj, 10, 2023
7QNH
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CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT N151G, L259V COMPLEXED WITH FE, NADH, AND GLYCEROL
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FE (III) ION, GLYCEROL, ...
著者Sridhar, S, Kiema, T.R, Wierenga, R.K, Widersten, M.
登録日2021-12-20
公開日2022-12-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity.
Iucrj, 10, 2023
7QLQ
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CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT N151G, L259V COMPLEXED WITH FE, NAD, AND DIMETHOXYPHENYL ACETAMIDE
分子名称: 2-(3,4-dimethoxyphenyl)ethanamide, ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, ...
著者Sridhar, S, Kiema, T.R, Widersten, M, Wierenga, R.K.
登録日2021-12-20
公開日2022-12-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity.
Iucrj, 10, 2023
4PCF
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Structure-based protein engineering of a monomeric triosephosphate isomerase towards changing substrate specificity
分子名称: Ma18-TIM
著者Krause, M, Neubauer, P, Wierenga, R.K.
登録日2014-04-15
公開日2015-04-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal structures of two monomeric triosephosphate isomerase variants identified via a directed-evolution protocol selecting for L-arabinose isomerase activity.
Acta Crystallogr.,Sect.F, 72, 2016

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