6HRV

Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1)

Summary for 6HRV

• Entry DOI: 10.2210/pdb6hrv/pdb
• Descriptor: SCP2-thiolase (type-1), GLYCEROL, ACETATE ION, ... (5 entities in total)
• Functional Keywords: fatty acid metabolism, bile acid biosynthesis, peroxisomal beta-oxidation, thiolytic cleavage, transferase
• Biological source: Danio rerio (Zebrafish); More
• Total number of polymer chains: 2
• Total formula weight: 91777.34

Authors

Wierenga, R.K.,Kiema, T.R.,Thapa, C.J. (deposition date: 2018-09-28, release date: 2019-01-02, Last modification date: 2024-01-24)

• Primary citation: Kiema, T.R.,Thapa, C.J.,Laitaoja, M.,Schmitz, W.,Maksimainen, M.M.,Fukao, T.,Rouvinen, J.,Janis, J.,Wierenga, R.K.; The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.; Biochem. J., 476:307-332, 2019; PubMed: 30573650; DOI: 10.1042/BCJ20180788

Experimental method

X-RAY DIFFRACTION (1.95 Å)