2ONW
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2Z9H
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![BU of 2z9h by Molmil](/molmil-images/mine/2z9h) | Ethanolamine utilization protein, EutN | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, Ethanolamine utilization protein eutN | Authors: | Tanaka, S, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2007-09-20 | Release date: | 2007-10-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | The crystal structure of ethanolamine utilization protein EutN from E. coli To be Published
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6VGS
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![BU of 6vgs by Molmil](/molmil-images/mine/6vgs) | Alpha-ketoisovalerate decarboxylase (KivD) from Lactococcus lactis, thermostable mutant | Descriptor: | Alpha-keto acid decarboxylase, MAGNESIUM ION, THIAMINE DIPHOSPHATE | Authors: | Chan, S, Korman, T.P, Sawaya, M.R, Bowie, J.U. | Deposit date: | 2020-01-08 | Release date: | 2020-08-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Isobutanol production freed from biological limits using synthetic biochemistry. Nat Commun, 11, 2020
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6BZM
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![BU of 6bzm by Molmil](/molmil-images/mine/6bzm) | GFGNFGTS from low-complexity/FG repeat domain of Nup98, residues 116-123 | Descriptor: | Nuclear pore complex protein Nup98-Nup96 | Authors: | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Chong, L, Gonen, T, Eisenberg, D.S. | Deposit date: | 2017-12-24 | Release date: | 2018-04-04 | Last modified: | 2024-03-13 | Method: | ELECTRON CRYSTALLOGRAPHY (0.9 Å) | Cite: | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
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5K2H
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3K6V
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![BU of 3k6v by Molmil](/molmil-images/mine/3k6v) | M. acetivorans Molybdate-Binding Protein (ModA) in Citrate-Bound Open Form | Descriptor: | CITRIC ACID, Solute-binding protein MA_0280 | Authors: | Chan, S, Giuroiu, I, Chernishof, I, Sawaya, M.R, Chiang, J, Gunsalus, R.P, Arbing, M.A, Perry, L.J. | Deposit date: | 2009-10-09 | Release date: | 2010-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Apo and ligand-bound structures of ModA from the archaeon Methanosarcina acetivorans Acta Crystallogr.,Sect.F, 66, 2010
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6C3G
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6CU7
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![BU of 6cu7 by Molmil](/molmil-images/mine/6cu7) | Alpha Synuclein fibril formed by full length protein - Rod Polymorph | Descriptor: | Alpha-synuclein | Authors: | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | Deposit date: | 2018-03-23 | Release date: | 2018-09-12 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9, 2018
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3K6X
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![BU of 3k6x by Molmil](/molmil-images/mine/3k6x) | M. acetivorans Molybdate-Binding Protein (ModA) in Molybdate-Bound Close Form with 2 Molecules in Asymmetric Unit Forming Beta Barrel | Descriptor: | MOLYBDATE ION, SULFATE ION, Solute-binding protein MA_0280 | Authors: | Chan, S, Chernishof, I, Giuroiu, I, Sawaya, M.R, Chiang, J, Gunsalus, R.P, Arbing, M.A, Perry, L.J. | Deposit date: | 2009-10-09 | Release date: | 2010-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Apo and ligand-bound structures of ModA from the archaeon Methanosarcina acetivorans Acta Crystallogr.,Sect.F, 66, 2010
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5K7R
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![BU of 5k7r by Molmil](/molmil-images/mine/5k7r) | MicroED structure of trypsin at 1.7 A resolution | Descriptor: | CALCIUM ION, Cationic trypsin | Authors: | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | Deposit date: | 2016-05-26 | Release date: | 2017-04-05 | Last modified: | 2018-08-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.7 Å) | Cite: | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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4RIK
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![BU of 4rik by Molmil](/molmil-images/mine/4rik) | Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77 | Descriptor: | Alpha-synuclein | Authors: | Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S. | Deposit date: | 2014-10-06 | Release date: | 2015-08-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.854 Å) | Cite: | Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525, 2015
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4RIL
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![BU of 4ril by Molmil](/molmil-images/mine/4ril) | Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction | Descriptor: | Alpha-synuclein | Authors: | Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S. | Deposit date: | 2014-10-06 | Release date: | 2015-08-26 | Last modified: | 2023-09-20 | Method: | ELECTRON CRYSTALLOGRAPHY (1.43 Å) | Cite: | Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525, 2015
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6C88
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5K2G
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6CU8
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![BU of 6cu8 by Molmil](/molmil-images/mine/6cu8) | Alpha Synuclein fibril formed by full length protein - Twister Polymorph | Descriptor: | Alpha-synuclein | Authors: | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | Deposit date: | 2018-03-23 | Release date: | 2018-09-12 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9, 2018
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3K6U
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![BU of 3k6u by Molmil](/molmil-images/mine/3k6u) | M. acetivorans Molybdate-Binding Protein (ModA) in Unliganded Open Form | Descriptor: | Solute-binding protein MA_0280 | Authors: | Chan, S, Giuroiu, I, Chernishof, I, Sawaya, M.R, Chiang, J, Gunsalus, R.P, Arbing, M.A, Perry, L.J. | Deposit date: | 2009-10-09 | Release date: | 2010-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Apo and ligand-bound structures of ModA from the archaeon Methanosarcina acetivorans Acta Crystallogr.,Sect.F, 66, 2010
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5K7N
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![BU of 5k7n by Molmil](/molmil-images/mine/5k7n) | MicroED structure of tau VQIVYK peptide at 1.1 A resolution | Descriptor: | VQIVYK | Authors: | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | Deposit date: | 2016-05-26 | Release date: | 2017-04-05 | Last modified: | 2024-02-28 | Method: | ELECTRON CRYSTALLOGRAPHY (1.1 Å) | Cite: | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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4QXX
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6CB9
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![BU of 6cb9 by Molmil](/molmil-images/mine/6cb9) | Segment AALQSS from the low complexity domain of TDP-43, residues 328-333 | Descriptor: | AALQSS | Authors: | Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2018-02-02 | Release date: | 2018-04-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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6CEW
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![BU of 6cew by Molmil](/molmil-images/mine/6cew) | Segment AMMAAA from the low complexity domain of TDP-43, residues 321-326 | Descriptor: | AMMAAA | Authors: | Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2018-02-12 | Release date: | 2018-04-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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3BN4
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![BU of 3bn4 by Molmil](/molmil-images/mine/3bn4) | Carboxysome Subunit, CcmK1 | Descriptor: | Carbon dioxide-concentrating mechanism protein ccmK homolog 1, SULFATE ION | Authors: | Tanaka, S, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2007-12-13 | Release date: | 2008-03-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Atomic-level models of the bacterial carboxysome shell. Science, 319, 2008
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3H87
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![BU of 3h87 by Molmil](/molmil-images/mine/3h87) | Rv0301 Rv0300 Toxin Antitoxin Complex from Mycobacterium tuberculosis | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, IMIDAZOLE, ... | Authors: | Min, A, Sawaya, M.R, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI) | Deposit date: | 2009-04-28 | Release date: | 2009-05-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg(2+) ion in the active site and a putative RNA-binding site. Protein Sci., 21, 2012
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6DIX
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![BU of 6dix by Molmil](/molmil-images/mine/6dix) | NFVFGT segment from Human Immunoglobulin Light-Chain Variable Domain, Residues 98-103, assembled as an amyloid fibril | Descriptor: | NFVFGT Immunoglobulin Light-Chain Variable Domain | Authors: | Brumshtein, B, Esswein, S.R, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2018-05-23 | Release date: | 2018-10-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis. J. Biol. Chem., 293, 2018
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4H88
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![BU of 4h88 by Molmil](/molmil-images/mine/4h88) | Structure of POM1 FAB fragment complexed with mouse PrPc Fragment 120-230 | Descriptor: | Major prion protein, POM1 FAB CHAIN H, POM1 FAB CHAIN L, ... | Authors: | Baral, P.K, Wieland, B, Swayampakula, M, James, M.N. | Deposit date: | 2012-09-21 | Release date: | 2013-07-31 | Last modified: | 2013-09-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature, 501, 2013
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5E5V
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![BU of 5e5v by Molmil](/molmil-images/mine/5e5v) | Structure of amyloid forming peptide NFGAILS (residues 22-28) from Islet Amyloid Polypeptide | Descriptor: | NFGAILS (22-28) from islet amyloid polypeptide, synthesized | Authors: | Soriaga, A.B, Macdonald, R, Sawaya, M.R, Sangwan, S, Eisenberg, D. | Deposit date: | 2015-10-09 | Release date: | 2015-12-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets. J.Phys.Chem.B, 120, 2016
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