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PDB: 659 件
2ON9
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BU of 2on9 by Molmil
Structure of an amyloid forming peptide VQIVYK from the repeat region of Tau
分子名称: VQIVYK peptide corresponding to residues 306-311 in the tau protein
著者Sambashivan, S, Sawaya, M.R, Eisenberg, D.
登録日2007-01-23
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
2OLX
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BU of 2olx by Molmil
Structure of NNQQ Peptide from Yeast Prion SUP35
分子名称: NNQQ peptide derived from Yeast Prion Sup35
著者Nelson, R, Sawaya, M.R, Eisenberg, D.
登録日2007-01-19
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
2ONA
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BU of 2ona by Molmil
MVGGVV peptide derived from Alzheimer's A-beta, residues 35-40
分子名称: MVGGVV peptide derived from Alzheimer's A-beta, residues 35-40
著者Sambashivan, S, Sawaya, M.R, Eisenberg, D.
登録日2007-01-23
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
6CF4
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BU of 6cf4 by Molmil
Segment NFGTFS, with familial mutation A315T and phosphorylated threonine, from the low complexity domain of TDP-43, residues 312-317
分子名称: NFGTFS
著者Guenther, E.L, Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-13
公開日2018-05-23
最終更新日2021-06-30
実験手法ELECTRON CRYSTALLOGRAPHY (0.75 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
2OL9
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BU of 2ol9 by Molmil
Peptide corresponding to residues 170-175 of human prion
分子名称: peptide from human prion
著者Apostol, M.A, Sawaya, M.R, Eisenberg, D.
登録日2007-01-18
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
2OMP
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BU of 2omp by Molmil
LYQLEN peptide derived from human insulin chain A, residues 13-18
分子名称: LYQLEN peptide derived from human insulin chain A, residues 13-18
著者Ivanova, M.I, Sawaya, M.R, Eisenberg, D.
登録日2007-01-22
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
2ONV
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BU of 2onv by Molmil
Crystal Structure of the amyloid-fibril forming peptide GGVVIA derived from the Alzheimer's amyloid Abeta (Abeta37-42).
分子名称: amyloid-fibril forming peptide GGVVIA derived from the Alzheimer's amyloid Abeta
著者Sambashivan, S, Sawaya, M.R, Eisenberg, D.
登録日2007-01-24
公開日2007-02-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
3FOD
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BU of 3fod by Molmil
AILSST segment from Islet Amyloid Polypeptide
分子名称: AILSST hexapeptide segment from Islet Amyloid Polypeptide
著者Wiltzius, J.J.W, Sawaya, M.R, Rajashankar, K, Eisenberg, D.
登録日2008-12-29
公開日2009-05-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular mechanisms for protein-encoded inheritance.
Nat.Struct.Mol.Biol., 16, 2009
2ONW
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BU of 2onw by Molmil
Structure of SSTSSA, a fibril forming peptide from Bovine Pancreatic Ribonuclease (RNase A, residues 15-20)
分子名称: fibril forming peptide from Bovine Pancreatic Ribonuclease (RNase A)
著者Sambashivan, S, Sawaya, M.R, Eisenberg, D.
登録日2007-01-24
公開日2007-02-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
3LE4
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BU of 3le4 by Molmil
Crystal structure of the DGCR8 dimerization domain
分子名称: Microprocessor complex subunit DGCR8
著者Senturia, R, Cascio, D, Sawaya, M, Guo, F.
登録日2010-01-14
公開日2010-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Structure of the dimerization domain of DiGeorge Critical Region 8
Protein Sci., 19, 2010
4DGI
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BU of 4dgi by Molmil
Structure of POM1 FAB fragment complexed with human PrPc Fragment 120-230
分子名称: Major prion protein, POM1 Fab Heavy chain, POM1 Fab Light chain, ...
著者Baral, P.K, Wieland, B, Swayampakula, M, James, M.N.
登録日2012-01-26
公開日2012-10-31
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1.
Acta Crystallogr.,Sect.D, 68, 2012
6O4J
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BU of 6o4j by Molmil
Amyloid Beta KLVFFAENVGS 16-26 D23N Iowa mutation
分子名称: Amyloid-beta precursor protein
著者Griner, S.L, Sawaya, M.R, Rodriguez, J.A, Cascio, D, Gonen, T.
登録日2019-02-28
公開日2019-10-30
最終更新日2023-10-11
実験手法ELECTRON CRYSTALLOGRAPHY (1.402 Å)
主引用文献Structure based inhibitors of Amyloid Beta core suggest a common interface with Tau.
Elife, 8, 2019
6PES
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BU of 6pes by Molmil
Cryo-EM structure of alpha-synuclein H50Q Wide Fibril
分子名称: Alpha-synuclein
著者Boyer, D.R, Li, B, Sawaya, M.R, Jiang, L, Eisenberg, D.S.
登録日2019-06-20
公開日2019-11-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of fibrils formed by alpha-synuclein hereditary disease mutant H50Q reveal new polymorphs.
Nat.Struct.Mol.Biol., 26, 2019
2OMQ
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BU of 2omq by Molmil
VEALYL peptide derived from human insulin chain B, residues 12-17
分子名称: VEALYL peptide derived from human insulin chain B, residues 12-17
著者Ivanova, M, Sawaya, M.R, Eisenberg, D.
登録日2007-01-22
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
3DN9
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BU of 3dn9 by Molmil
Carboxysome Subunit, CcmK1 C-terminal deletion mutant
分子名称: CcmK1 C-terminal deletion mutant, SULFATE ION
著者Tanaka, S, Sawaya, M.R, Yeates, T.O.
登録日2008-07-01
公開日2009-01-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Insights from multiple structures of the shell proteins from the beta-carboxysome.
Protein Sci., 18, 2009
6B79
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BU of 6b79 by Molmil
Curved pair of sheets formed from SOD1 residues 28-38 with familial mutation G37R.
分子名称: 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid, Superoxide dismutase [Cu-Zn]
著者Sangwan, S, Sawaya, M.R, Eisenberg, D.S.
登録日2017-10-03
公開日2018-05-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations.
Protein Sci., 27, 2018
4EFH
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BU of 4efh by Molmil
Acanthamoeba Actin complex with Spir domain D
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-1, CALCIUM ION, ...
著者Chen, C, Phillips, M, Sawaya, M.R, Quinlan, M.E.
登録日2012-03-29
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Multiple Forms of Spire-Actin Complexes and their Functional Consequences.
J.Biol.Chem., 287, 2012
3FPO
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BU of 3fpo by Molmil
HSSNNF segment from Islet Amyloid Polypeptide (IAPP or Amylin)
分子名称: HSSNNF hexapeptide segment from Islet Amyloid Polypeptide
著者Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D.
登録日2009-01-05
公開日2009-06-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular mechanisms for protein-encoded inheritance.
Nat.Struct.Mol.Biol., 16, 2009
3FTH
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BU of 3fth by Molmil
NFLVHSS segment from Islet Amyloid Polypeptide (IAPP or Amylin)
分子名称: NFLVHSS heptapeptide from Islet Amyloid Polypeptide, SULFATE ION
著者Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D.
登録日2009-01-13
公開日2009-06-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Molecular mechanisms for protein-encoded inheritance
Nat.Struct.Mol.Biol., 16, 2009
3FTL
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BU of 3ftl by Molmil
NVGSNTY segment from Islet Amyloid Polypeptide (IAPP or Amylin), dehydrated crystal form
分子名称: NVGSNTY heptapeptide segment from Islet Amyloid Polypeptide
著者Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D.
登録日2009-01-13
公開日2009-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular mechanisms for protein-encoded inheritance
Nat.Struct.Mol.Biol., 16, 2009
3SGR
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BU of 3sgr by Molmil
Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L
著者Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2011-06-15
公開日2012-03-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
6E74
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BU of 6e74 by Molmil
Structure of Human Transthyretin Leu55Pro Mutant in Complex with Tafamidis
分子名称: 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin
著者Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2018-07-25
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Variants of Transthyretin
To Be Published
3K6W
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BU of 3k6w by Molmil
Apo and ligand bound structures of ModA from the archaeon Methanosarcina acetivorans
分子名称: MOLYBDATE ION, SULFATE ION, Solute-binding protein MA_0280
著者Chan, S, Chernishof, I, Giuroiu, I, Sawaya, M.R, Chiang, J, Gunsalus, R.P, Arbing, M.A, Perry, L.J.
登録日2009-10-09
公開日2010-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Apo and ligand-bound structures of ModA from the archaeon Methanosarcina acetivorans
Acta Crystallogr.,Sect.F, 66, 2010
6BCS
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BU of 6bcs by Molmil
LilrB2 D1D2 domains complexed with benzamidine
分子名称: BENZAMIDINE, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Cao, Q, Sawaya, M.R, Eisenberg, D.S.
登録日2017-10-20
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Inhibiting amyloid-beta cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design.
Nat Chem, 10, 2018
3FR1
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BU of 3fr1 by Molmil
NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin)
分子名称: CHLORIDE ION, Islet amyloid polypeptide
著者Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D.
登録日2009-01-08
公開日2009-06-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular mechanisms for protein-encoded inheritance
Nat.Struct.Mol.Biol., 16, 2009

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