6O4J
Amyloid Beta KLVFFAENVGS 16-26 D23N Iowa mutation
Summary for 6O4J
| Entry DOI | 10.2210/pdb6o4j/pdb |
| EMDB information | 0619 |
| Descriptor | Amyloid-beta precursor protein (1 entity in total) |
| Functional Keywords | amyloid, protein fibril |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 2470.86 |
| Authors | Griner, S.L.,Sawaya, M.R.,Rodriguez, J.A.,Cascio, D.,Gonen, T. (deposition date: 2019-02-28, release date: 2019-10-30, Last modification date: 2023-10-11) |
| Primary citation | Griner, S.L.,Seidler, P.,Bowler, J.,Murray, K.A.,Yang, T.P.,Sahay, S.,Sawaya, M.R.,Cascio, D.,Rodriguez, J.A.,Philipp, S.,Sosna, J.,Glabe, C.G.,Gonen, T.,Eisenberg, D.S. Structure based inhibitors of Amyloid Beta core suggest a common interface with Tau. Elife, 8:-, 2019 Cited by PubMed: 31612856DOI: 10.7554/eLife.46924 PDB entries with the same primary citation |
| Experimental method | ELECTRON CRYSTALLOGRAPHY (1.402 Å) |
Structure validation
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