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PDB: 659 results

2A5X
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Crystal Structure of a Cross-linked Actin Dimer
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Actin, alpha skeletal muscle, ...
Authors:Kudryashov, D.S, Sawaya, M.R, Adisetiyo, H, Norcross, T, Hegyi, G, Reisler, E, Yeates, T.O.
Deposit date:2005-07-01
Release date:2005-08-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin
Proc.Natl.Acad.Sci.Usa, 102, 2005
1F1C
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CRYSTAL STRUCTURE OF CYTOCHROME C549
Descriptor: CYTOCHROME C549, HEME C
Authors:Kerfeld, C.A, Sawaya, M.R, Yeates, T.O, Krogmann, D.W.
Deposit date:2000-05-18
Release date:2001-08-08
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima.
Biochemistry, 40, 2001
4OLP
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Ligand-free structure of the GrpU microcompartment shell protein from Pectobacterium wasabiae
Descriptor: GrpU microcompartment shell protein
Authors:Wheatley, N.M, Thompson, M.C, Gidaniyan, S.D, Sawaya, M.R, Jorda, J, Yeates, T.O.
Deposit date:2014-01-24
Release date:2014-07-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Identification of a unique fe-s cluster binding site in a glycyl-radical type microcompartment shell protein.
J.Mol.Biol., 426, 2014
4NIP
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GVIGIAQ segment 147-153 from Human Superoxide Dismutase
Descriptor: GVTGIAQ segment from Superoxide dismutase [Cu-Zn]
Authors:Sievers, S.A, Sawaya, M.R, Eisenberg, D, Ivanova, M.I.
Deposit date:2013-11-06
Release date:2013-12-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NIO
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GVTGIAQ segment 147-153 from Human Superoxide Dismutase with I149T mutation associated with a familial form of amyotrophic lateral sclerosis
Descriptor: GVTGIAQ segment from Superoxide dismutase [Cu-Zn]
Authors:Sievers, S.A, Sawaya, M.R, Eisenberg, D, Ivanova, M.I.
Deposit date:2013-11-06
Release date:2013-12-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
1OY0
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The crystal Structure of the First Enzyme of Pantothenate Biosynthetic Pathway, Ketopantoate Hydroxymethyltransferase from Mycobacterium Tuberculosis Shows a Decameric Assembly and Terminal Helix-Swapping
Descriptor: Ketopantoate hydroxymethyltransferase, MAGNESIUM ION
Authors:Chaudhuri, B.N, Sawaya, M.R, Kim, C.Y, Waldo, G.S, Park, M.S, Terwilliger, T.C, Yeates, T.O, TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-04-03
Release date:2003-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of the First Enzyme in the Pantothenate Biosynthetic Pathway, Ketopantoate Hydroxymethyltransferase, from M. tuberculosis
Structure, 11, 2003
1F1F
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CRYSTAL STRUCTURE OF CYTOCHROME C6 FROM ARTHROSPIRA MAXIMA
Descriptor: CYTOCHROME C6, HEME C
Authors:Kerfeld, C.A, Serag, A.A, Sawaya, M.R, Krogmann, D.W, Yeates, T.O.
Deposit date:2000-05-18
Release date:2001-08-08
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima.
Biochemistry, 40, 2001
1L9L
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GRANULYSIN FROM HUMAN CYTOLYTIC T LYMPHOCYTES
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ETHANOL, Granulysin, ...
Authors:Anderson, D.H, Sawaya, M.R, Cascio, D, Ernst, W, Krensky, A, Modlin, R, Eisenberg, D.
Deposit date:2002-03-25
Release date:2002-11-06
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism
J.Mol.Biol., 325, 2002
4MYP
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Structure of the central NEAT domain, N2, of the listerial Hbp2 protein complexed with heme
Descriptor: GLYCEROL, Iron-regulated surface determinant protein A, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Malmirchegini, G.R, Sawaya, M.R, Clubb, R.T.
Deposit date:2013-09-27
Release date:2014-10-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Novel Mechanism of Hemin Capture by Hbp2, the Hemoglobin-binding Hemophore from Listeria monocytogenes.
J.Biol.Chem., 289, 2014
1E0K
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gp4d helicase from phage T7
Descriptor: DNA HELICASE
Authors:Singleton, M.R, Sawaya, M.R, Ellenberger, T, Wigley, D.B.
Deposit date:2000-03-30
Release date:2000-06-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structure of T7 Gene 4 Ring Helicase Indicates a Mechanism for Sequential Hydrolysis of Nucleotides
Cell(Cambridge,Mass.), 101, 2000
1E0J
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gp4d helicase from phage T7 ADPNP complex
Descriptor: DNA HELICASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Singleton, M.R, Sawaya, M.R, Ellenberger, T, Wigley, D.B.
Deposit date:2000-03-30
Release date:2000-06-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of T7 Gene 4 Ring Helicase Indicates a Mechanism for Sequential Hydrolysis of Nucleotides
Cell(Cambridge,Mass.), 101, 2000
1KIB
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cytochrome c6 from Arthrospira maxima: an assembly of 24 subunits in the form of an oblate shell
Descriptor: HEME C, cytochrome c6
Authors:Kerfeld, C.A, Sawaya, M.R, Krogmann, D, Yeates, T.O.
Deposit date:2001-12-03
Release date:2002-07-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of cytochrome c6 from Arthrospira maxima: an assembly of 24 subunits in a nearly symmetric shell.
Acta Crystallogr.,Sect.D, 58, 2002
1EKV
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HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL): THREE DIMENSIONAL STRUCTURE OF ENZYME INACTIVATED BY TRIS BOUND TO THE PYRIDOXAL-5'-PHOSPHATE ON ONE END AND ACTIVE SITE LYS202 NZ ON THE OTHER.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL), PYRIDOXAL-5'-PHOSPHATE
Authors:Yennawar, N.H, Dunbar, J.H, Conway, M, Hutson, S.M, Farber, G.K.
Deposit date:2000-03-09
Release date:2001-03-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The structure of human mitochondrial branched-chain aminotransferase.
Acta Crystallogr.,Sect.D, 57, 2001
1EKP
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CRYSTAL STRUCTURE OF HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL) COMPLEXED WITH PYRIDOXAL-5'-PHOSPHATE AT 2.5 ANGSTROMS (MONOCLINIC FORM).
Descriptor: BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL), PYRIDOXAL-5'-PHOSPHATE
Authors:Yennawar, N.H, Dunbar, J.H, Conway, M, Hutson, S.M, Farber, G.K.
Deposit date:2000-03-09
Release date:2001-03-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of human mitochondrial branched-chain aminotransferase.
Acta Crystallogr.,Sect.D, 57, 2001
4R0U
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Tgvtava, an amyloid forming segment from alpha synuclein, residues 72-78
Descriptor: Alpha-synuclein
Authors:Ivanova, M.I, Eisenberg, D.S, Sawaya, M.R.
Deposit date:2014-08-01
Release date:2014-12-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
4R0P
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Ifqins, an amyloid forming segment from human lysozyme spanning residues 56-61
Descriptor: Lysozyme C
Authors:Sievers, S, Eisenberg, D.S, Sawaya, M.R.
Deposit date:2014-08-01
Release date:2014-12-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
4MJH
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BU of 4mjh by Molmil
Human Hsp27 core domain in complex with C-terminal peptide
Descriptor: Heat shock protein beta-1
Authors:Laganowsky, A, Cascio, D, Sawaya, M.R, Eisenberg, D.
Deposit date:2013-09-03
Release date:2014-04-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NP8
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BU of 4np8 by Molmil
Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph)
Descriptor: Microtubule-associated protein tau
Authors:Landau, M, Eisenberg, D, Sawaya, M.R, Dannenberg, J, Kobko, N.
Deposit date:2013-11-20
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Molecular mechanisms for protein-encoded inheritance.
Nat.Struct.Mol.Biol., 16, 2009
6D12
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BU of 6d12 by Molmil
Crystal structure of C-terminal xRRM domain of human Larp7 bound to 7SK stem-loop 4 RNA
Descriptor: La-related protein 7, human 7SK RNA stem-loop 4
Authors:Eichhorn, C.D, Cascio, D, Sawaya, M.R, Feigon, J.
Deposit date:2018-04-11
Release date:2018-06-27
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4NIN
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BU of 4nin by Molmil
DSVISLS segment 101-107 from Human Superoxide Dismutase
Descriptor: DSVISLS segment from Superoxide dismutase [Cu-Zn], ZINC ION
Authors:Sievers, S.A, Sawaya, M.R, Eisenberg, D.
Deposit date:2013-11-06
Release date:2013-12-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
1NOM
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BU of 1nom by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF MNCL2 (5 MILLIMOLAR)
Descriptor: DNA POLYMERASE BETA, MANGANESE (II) ION
Authors:Pelletier, H, Sawaya, M.R.
Deposit date:1996-04-19
Release date:1996-11-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis.
Biochemistry, 35, 1996
1I8F
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THE CRYSTAL STRUCTURE OF A HEPTAMERIC ARCHAEAL SM PROTEIN: IMPLICATIONS FOR THE EUKARYOTIC SNRNP CORE
Descriptor: GLYCEROL, PUTATIVE SNRNP SM-LIKE PROTEIN
Authors:Mura, C, Cascio, D, Sawaya, M.R, Eisenberg, D.
Deposit date:2001-03-14
Release date:2001-05-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core.
Proc.Natl.Acad.Sci.USA, 98, 2001
4NLA
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Structure of the central NEAT domain, N2, of the listerial Hbp2 protein, apo form
Descriptor: Iron-regulated surface determinant protein A, SULFATE ION
Authors:Malmirchegini, G.R, Sawaya, M.R, Clubb, R.T.
Deposit date:2013-11-14
Release date:2014-10-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Novel Mechanism of Hemin Capture by Hbp2, the Hemoglobin-binding Hemophore from Listeria monocytogenes.
J.Biol.Chem., 289, 2014
1S3Q
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Crystal structures of a novel open pore ferritin from the hyperthermophilic Archaeon Archaeoglobus fulgidus
Descriptor: ZINC ION, ferritin
Authors:Johnson, E, Cascio, D, Sawaya, M, Schroeder, I.
Deposit date:2004-01-13
Release date:2005-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus.
Structure, 13, 2005
1NPA
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crystal structure of HIV-1 protease-hup
Descriptor: (3S)-TETRAHYDROFURAN-3-YL (1R,2S)-3-[4-((1R)-2-{[(S)-AMINO(HYDROXY)METHYL]OXY}-2,3-DIHYDRO-1H-INDEN-1-YL)-2-BENZYL-3-OXOPYRROLIDIN-2-YL]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, POL polyprotein
Authors:Smith III, A.B, Hirschmann, R, Pasternak, A, Yao, W, Sprengeler, P.A, Holloway, M.K, Kuo, L.C, Chen, Z, Darke, P.L, Schleif, W.A.
Deposit date:2003-01-17
Release date:2004-01-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:An orally bioavailable pyrrolinone inhibitor of HIV-1 protease: computational analysis and X-ray crystal structure of the enzyme complex.
J.MED.CHEM., 40, 1997

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