8HXA
 
 | | Cryo-EM structure of MPXV M2 in complex with human B7.1 | | 分子名称: | NFkB inhibitor, T-lymphocyte activation antigen CD80 | | 著者 | Wang, Y, Yang, S, Zhao, H, Deng, Z. | | 登録日 | 2023-01-04 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2.
Nat Commun, 14, 2023
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8HXB
 | | Cryo-EM structure of MPXV M2 hexamer in complex with human B7.2 | | 分子名称: | NFkB inhibitor, T-lymphocyte activation antigen CD86 | | 著者 | Wang, Y, Yang, S, Zhao, H, Deng, Z. | | 登録日 | 2023-01-04 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2.
Nat Commun, 14, 2023
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8HXC
 | | Cryo-EM structure of MPXV M2 heptamer in complex with human B7.2 | | 分子名称: | NFkB inhibitor, T-lymphocyte activation antigen CD86 | | 著者 | Wang, Y, Yang, S, Zhao, H, Deng, Z. | | 登録日 | 2023-01-04 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2.
Nat Commun, 14, 2023
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6LK0
 | | Crystal structure of human wild type TRIP13 | | 分子名称: | Pachytene checkpoint protein 2 homolog | | 著者 | Wang, Y, Huang, J, Li, B, Xue, H, Tricot, G, Hu, L, Xu, Z, Sun, X, Chang, S, Gao, L, Tao, Y, Xu, H, Xie, Y, Xiao, W, Yu, D, Kong, Y, Chen, G, Sun, X, Lian, F, Zhang, N, Wu, X, Mao, Z, Zhan, F, Zhu, W, Shi, J. | | 登録日 | 2019-12-17 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Cancer Res., 80, 2020
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8I2B
 | | Human SIRT6 in complex with inhibitor 7702 | | 分子名称: | N1-[[4-(4-aminophenyl)sulfanyl-3-(trifluoromethyl)phenyl]methoxy]benzene-1,4-dicarboxamide, NAD-dependent protein deacylase sirtuin-6, SULFATE ION, ... | | 著者 | Wang, Y. | | 登録日 | 2023-01-14 | | 公開日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The SIRT6 in complex with inhibitor 7702
To Be Published
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6M5F
 | | Crystal structure of HinK, a LysR family transcriptional regulator from Pseudomonas aeruginosa | | 分子名称: | Probable transcriptional regulator | | 著者 | Wang, Y, Lan, L, Cao, Q, Gan, J, Wang, F. | | 登録日 | 2020-03-10 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structure of HinK, a LysR family transcriptional regulator from Pseudomonas aeruginosa
To Be Published
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7X7E
 | | SARS-CoV-2 RBD and Nb22 | | 分子名称: | Nb22, Spike protein S1, TETRAETHYLENE GLYCOL | | 著者 | Wang, Y, Ye, S. | | 登録日 | 2022-03-09 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22).
Front Immunol, 13, 2022
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7X7D
 | | SARS-CoV-2 Delta RBD and Nb22 | | 分子名称: | Nb22, Spike protein S1 | | 著者 | Wang, Y, Ye, S. | | 登録日 | 2022-03-09 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22).
Front Immunol, 13, 2022
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7EK4
 | | prawn ferritin to coordinate with heavy metal ions | | 分子名称: | FE (III) ION, Ferritin, MERCURY (II) ION | | 著者 | Wang, Y, Zang, J. | | 登録日 | 2021-04-03 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Insights for the Stronger Ability of Shrimp Ferritin to Coordinate with Heavy Metal Ions as Compared to Human H-Chain Ferritin.
Int J Mol Sci, 22, 2021
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7EK7
 | | prawn ferritin to coordinate with heavy metal ions | | 分子名称: | Ferritin, MERCURY (II) ION | | 著者 | Wang, Y, Zang, J. | | 登録日 | 2021-04-04 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Insights for the Stronger Ability of Shrimp Ferritin to Coordinate with Heavy Metal Ions as Compared to Human H-Chain Ferritin.
Int J Mol Sci, 22, 2021
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7EK5
 | | prawn ferritin to coordinate with heavy metal ions | | 分子名称: | CADMIUM ION, FE (III) ION, Ferritin | | 著者 | Wang, Y, Zang, J. | | 登録日 | 2021-04-03 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Insights for the Stronger Ability of Shrimp Ferritin to Coordinate with Heavy Metal Ions as Compared to Human H-Chain Ferritin.
Int J Mol Sci, 22, 2021
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5Y8V
 | | Crystal structure of GAS41 | | 分子名称: | MAGNESIUM ION, YEATS domain-containing protein 4 | | 著者 | Wang, Y, Hao, Q. | | 登録日 | 2017-08-21 | | 公開日 | 2018-04-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8U2B
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7WO2
 | | SARS-CoV-2 3CLPro Peptidomimetic Inhibitor TPM5 | | 分子名称: | 3C-like proteinase, N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanylidene-3-[(3S}-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]furan-2-carboxamide | | 著者 | Wang, Y, Ye, S. | | 登録日 | 2022-01-20 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions.
Int J Mol Sci, 23, 2022
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8UCR
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8UEJ
 | | ssRNA phage PhiCb5 virion | | 分子名称: | CALCIUM ION, Coat protein, Maturation protein | | 著者 | Wang, Y, Zhang, J. | | 登録日 | 2023-10-01 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural mechanisms of Tad pilus assembly and its interaction with an RNA virus.
Sci Adv, 10, 2024
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7WOF
 | | SARS-CoV-2 3CLpro | | 分子名称: | (2S,3S)-3-methyl-N-[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-2-[[(E)-3-phenylprop-2-enoyl]amino]pentanamide, 3C-like proteinase | | 著者 | Wang, Y, Ye, S. | | 登録日 | 2022-01-21 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions.
Int J Mol Sci, 23, 2022
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7WO1
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7WOH
 | | SARS-CoV-2 3CLpro | | 分子名称: | (2S)-4-methyl-N-[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-2-[[(2S)-3-phenyl-2-[[(E)-3-phenylprop-2-enoyl]amino]propanoyl]amino]pentanamide, 3C-like proteinase | | 著者 | Wang, Y, Ye, S. | | 登録日 | 2022-01-21 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions.
Int J Mol Sci, 23, 2022
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7WO3
 | | SARS-CoV-2 3CLpro | | 分子名称: | (2S)-2-[[(2S)-2-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]-3-methyl-butanoyl]amino]-4-methyl-N-[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepiperidin-3-yl]propan-2-yl]pentanamide, 3C-like proteinase | | 著者 | Wang, Y, Ye, S. | | 登録日 | 2022-01-20 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions.
Int J Mol Sci, 23, 2022
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7Y3E
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5XKF
 | | Crystal structure of T2R-TTL-MPC6827 complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | | 著者 | Wang, Y, Yang, J, Wang, T, Chen, L. | | 登録日 | 2017-05-07 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Identification of a powerful and reversible microtubule-inhibitor with efficacy against multidrug-resistant tumors
To Be Published
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6BLQ
 | | Crystal Structure of IAg7 in complex with insulin mimotope p8E9E | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, Y, Dai, S. | | 登録日 | 2017-11-11 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BLX
 | | Crystal structure of IAg7 in complex with insulin mimotope p8G9E | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, Y, Dai, S. | | 登録日 | 2017-11-11 | | 公開日 | 2017-12-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.323 Å) | | 主引用文献 | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5XKE
 | | Crystal structure of T2R-TTL-Demecolcine complex | | 分子名称: | (7S)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, Y, Yang, J, Wang, T, Chen, L. | | 登録日 | 2017-05-07 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Identification of a powerful and reversible microtubule-inhibitor with efficacy against multidrug-resistant tumors
To Be Published
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