8HXA

Cryo-EM structure of MPXV M2 in complex with human B7.1

Summary for 8HXA

Entry DOI	10.2210/pdb8hxa/pdb
EMDB information	35074
Descriptor	NFkB inhibitor, T-lymphocyte activation antigen CD80 (2 entities in total)
Functional Keywords	m2, complex, immune evasion, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Monkeypox virus More
Total number of polymer chains	12
Total formula weight	277075.89
Authors	Wang, Y.,Yang, S.,Zhao, H.,Deng, Z. (deposition date: 2023-01-04, release date: 2023-08-30, Last modification date: 2023-12-13)
Primary citation	Yang, S.,Wang, Y.,Yu, F.,Cheng, R.,Zhang, Y.,Zhou, D.,Ren, X.,Deng, Z.,Zhao, H. Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2. Nat Commun, 14:5186-5186, 2023 Cited by PubMed: 37626059 DOI: 10.1038/s41467-023-40748-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.04 Å)

Structure validation