8HXA

Cryo-EM structure of MPXV M2 in complex with human B7.1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0019049	biological_process	virus-mediated perturbation of host defense response
A	0044165	cellular_component	host cell endoplasmic reticulum
A	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
B	0005576	cellular_component	extracellular region
B	0019049	biological_process	virus-mediated perturbation of host defense response
B	0044165	cellular_component	host cell endoplasmic reticulum
B	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
C	0005576	cellular_component	extracellular region
C	0019049	biological_process	virus-mediated perturbation of host defense response
C	0044165	cellular_component	host cell endoplasmic reticulum
C	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
D	0005576	cellular_component	extracellular region
D	0019049	biological_process	virus-mediated perturbation of host defense response
D	0044165	cellular_component	host cell endoplasmic reticulum
D	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
E	0005576	cellular_component	extracellular region
E	0019049	biological_process	virus-mediated perturbation of host defense response
E	0044165	cellular_component	host cell endoplasmic reticulum
E	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
F	0005576	cellular_component	extracellular region
F	0019049	biological_process	virus-mediated perturbation of host defense response
F	0044165	cellular_component	host cell endoplasmic reticulum
F	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
G	0015026	molecular_function	coreceptor activity
G	0031295	biological_process	T cell costimulation
H	0015026	molecular_function	coreceptor activity
H	0031295	biological_process	T cell costimulation
I	0015026	molecular_function	coreceptor activity
I	0031295	biological_process	T cell costimulation
J	0015026	molecular_function	coreceptor activity
J	0031295	biological_process	T cell costimulation
K	0015026	molecular_function	coreceptor activity
K	0031295	biological_process	T cell costimulation
L	0015026	molecular_function	coreceptor activity
L	0031295	biological_process	T cell costimulation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
A	ASN49
C	ASN79
C	ASN118
C	ASN154
D	ASN49
D	ASN79
D	ASN118
D	ASN154
E	ASN49
E	ASN79
E	ASN118
A	ASN79
E	ASN154
F	ASN49
F	ASN79
F	ASN118
F	ASN154
K	ASN226
L	ASN53
L	ASN89
L	ASN186
L	ASN207
A	ASN118
L	ASN226
A	ASN154
B	ASN49
B	ASN79
B	ASN118
B	ASN154
C	ASN49

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site_id	SWS_FT_FI2
Number of Residues	18
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
G	ASN98
J	ASN98
J	ASN211
J	ASN232
K	ASN98
K	ASN211
K	ASN232
L	ASN98
L	ASN211
L	ASN232
G	ASN211
G	ASN232
H	ASN98
H	ASN211
H	ASN232
I	ASN98
I	ASN211
I	ASN232

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