7C10
| Dithiol cGrx1 | Descriptor: | Glutaredoxin | Authors: | Lee, K, Hwang, K.Y. | Deposit date: | 2020-05-02 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.806 Å) | Cite: | Monothiol and dithiol glutaredoxin-1 from clostridium oremlandii: identification of domain-swapped structures by NMR, X-ray crystallography and HDX mass spectrometry. Iucrj, 7, 2020
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1B8U
| MALATE DEHYDROGENASE FROM AQUASPIRILLUM ARCTICUM | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXALOACETATE ION, PROTEIN (MALATE DEHYDROGENASE) | Authors: | Kim, S.Y, Hwang, K.Y, Kim, S.-H, Han, Y.S, Cho, Y. | Deposit date: | 1999-02-02 | Release date: | 1999-07-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum. J.Biol.Chem., 274, 1999
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1B8V
| Malate dehydrogenase from Aquaspirillum arcticum | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (MALATE DEHYDROGENASE) | Authors: | Kim, S.Y, Hwang, K.Y, Kim, S.H, Han, Y.S, Cho, Y. | Deposit date: | 1999-02-02 | Release date: | 1999-07-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum. J.Biol.Chem., 274, 1999
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2G04
| Crystal structure of fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv | Descriptor: | PROBABLE FATTY-ACID-CoA RACEMASE FAR | Authors: | Lee, K.S, Park, S.M, Rhee, K.H, Bang, W.G, Hwang, K.Y, Chi, Y.M. | Deposit date: | 2006-02-11 | Release date: | 2007-01-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv Proteins, 64, 2006
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7Y1H
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | Descriptor: | 1-(5-chloranyl-4-methyl-benzimidazol-1-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | Deposit date: | 2022-06-08 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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7Y1W
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | Descriptor: | (2R,3S)-2-[3-[4,5-bis(chloranyl)benzimidazol-1-yl]propyl]piperidin-3-ol, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | Deposit date: | 2022-06-09 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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7Y28
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | Descriptor: | 1-[6-(3-fluorophenyl)benzimidazol-1-yl]-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | Deposit date: | 2022-06-09 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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7Y3S
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | Descriptor: | 1-(6-bromanyl-7-methyl-imidazo[4,5-b]pyridin-3-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | Deposit date: | 2022-06-12 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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6AA7
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5CHI
| Crystal structure of PF2046 in complex with ssDNA | Descriptor: | DNA (5'-D(P*TP*TP*TP*T)-3'), MAGNESIUM ION, Uncharacterized protein | Authors: | Kim, J.S, Hwang, K.Y, Lee, W.C. | Deposit date: | 2015-07-10 | Release date: | 2016-08-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.472 Å) | Cite: | Structural basis of two-nucleotide removal of ssDNA by a cryptic RNase H fold 3'-5' exonuclease PF2046 from Pyrococcus furiosus to be published
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5CZY
| Crystal structure of LegAS4 | Descriptor: | GLYCEROL, Legionella effector LegAS4, S-ADENOSYLMETHIONINE | Authors: | Son, J, Hwang, K.Y, Lee, W.C. | Deposit date: | 2015-08-01 | Release date: | 2015-09-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Legionella pneumophila type IV secretion system effector LegAS4 Biochem.Biophys.Res.Commun., 465, 2015
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3L1I
| Crystal structure of EstE5, was soaked by CuSO4 | Descriptor: | Esterase/lipase | Authors: | Nam, K.H, Hwang, K.Y. | Deposit date: | 2009-12-11 | Release date: | 2010-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into the noninvasive inhibition of HSL-homolog EstE5 by organic solvents and metal ions To be Published
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1MZL
| MAIZE NONSPECIFIC LIPID TRANSFER PROTEIN | Descriptor: | MAIZE NONSPECIFIC LIPID TRANSFER PROTEIN | Authors: | Shin, D.H, Lee, J.Y, Hwang, K.Y, Kim, K.K, Suh, S.W. | Deposit date: | 1995-01-26 | Release date: | 1996-08-01 | Last modified: | 2018-03-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-resolution crystal structure of the non-specific lipid-transfer protein from maize seedlings. Structure, 3, 1995
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1L8L
| Molecular basis for the local confomational rearrangement of human phosphoserine phosphatase | Descriptor: | D-2-AMINO-3-PHOSPHONO-PROPIONIC ACID, L-3-phosphoserine phosphatase | Authors: | Kim, H.Y, Heo, Y.S, Kim, J.H, Park, M.H, Moon, J, Park, S.Y, Lee, T.G, Jeon, Y.H, Ro, S, Hwang, K.Y. | Deposit date: | 2002-03-21 | Release date: | 2003-04-01 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase. J.Biol.Chem., 277, 2002
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4Q2Y
| Crystal structure of Arginyl-tRNA synthetase | Descriptor: | Arginine--tRNA ligase, cytoplasmic | Authors: | Kim, H.S, Jo, C.H, Cha, S.Y, Han, A.R, Hwang, K.Y. | Deposit date: | 2014-04-10 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.799 Å) | Cite: | The crystal structure of arginyl-tRNA synthetase from Homo sapiens Febs Lett., 588, 2014
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4Q2T
| Crystal structure of Arginyl-tRNA synthetase complexed with L-arginine | Descriptor: | ARGININE, Arginine--tRNA ligase, cytoplasmic, ... | Authors: | Kim, H.S, Jo, C.H, Cha, S.Y, Han, A.R, Hwang, K.Y. | Deposit date: | 2014-04-09 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of arginyl-tRNA synthetase from Homo sapiens Febs Lett., 588, 2014
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1L8O
| Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase | Descriptor: | L-3-phosphoserine phosphatase, PHOSPHATE ION, SERINE | Authors: | Kim, H.Y, Heo, Y.S, Kim, J.H, Park, M.H, Moon, J, Park, S.Y, Lee, T.G, Jeon, Y.H, Ro, S, Hwang, K.Y. | Deposit date: | 2002-03-21 | Release date: | 2003-04-01 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase J.Biol.Chem., 277, 2002
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3L1J
| Crystal structure of EstE5, was soaked by ZnSO4 | Descriptor: | Esterase/lipase | Authors: | Nam, K.H, Hwang, K.Y. | Deposit date: | 2009-12-11 | Release date: | 2010-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the noninvasive inhibition of HSL-homolog EstE5 by organic solvents and metal ions To be Published
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3L1H
| Crystal structure of EstE5, was soaked by FeCl3 | Descriptor: | Esterase/lipase | Authors: | Nam, K.H, Hwang, K.Y. | Deposit date: | 2009-12-11 | Release date: | 2010-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into the noninvasive inhibition of HSL-homolog EstE5 by organic solvents and metal ions To be Published
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6KIE
| Crystal structure of human leucyl-tRNA synthetase, Leu-AMS-bound form | Descriptor: | 5'-O-(L-leucylsulfamoyl)adenosine, LEUCINE, Leucine--tRNA ligase, ... | Authors: | Kim, S, Son, J, Kim, S, Hwang, K.Y. | Deposit date: | 2019-07-18 | Release date: | 2021-01-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. Cell Rep, 35, 2021
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6KID
| Crystal structure of human leucyl-tRNA synthetase, ATP-bound form | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, LEUCINE, Leucine--tRNA ligase, ... | Authors: | Kim, S, Son, J, Kim, S, Hwang, K.Y. | Deposit date: | 2019-07-18 | Release date: | 2021-01-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. Cell Rep, 35, 2021
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3NJ4
| Fluoro-neplanocin A in Human S-Adenosylhomocysteine Hydrolase | Descriptor: | (4S,5S)-4-(6-amino-9H-purin-9-yl)-3-fluoro-5-hydroxy-2-(hydroxymethyl)cyclopent-2-en-1-one, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jeong, L.S, Lee, K.M, Hwang, K.Y, Choi, S, Heo, Y.S. | Deposit date: | 2010-06-17 | Release date: | 2011-05-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues. J.Med.Chem., 54, 2011
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3NGL
| Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum | Descriptor: | Bifunctional protein folD, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Sung, M.W, Lee, W.H, Hwang, K.Y. | Deposit date: | 2010-06-12 | Release date: | 2011-04-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum Biochem.Biophys.Res.Commun., 406, 2011
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4Q2X
| Crystal structure of Arginyl-tRNA synthetase complexed with L-canavanine | Descriptor: | Arginine--tRNA ligase, cytoplasmic, L-CANAVANINE | Authors: | Kim, H.S, Jo, C.H, Cha, S.Y, Han, A.R, Hwang, K.Y. | Deposit date: | 2014-04-10 | Release date: | 2014-07-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.798 Å) | Cite: | The crystal structure of arginyl-tRNA synthetase from Homo sapiens Febs Lett., 588, 2014
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6KQY
| Crystal structure of human leucyl-tRNA synthetase, Leucine-bound form | Descriptor: | LEUCINE, Leucine--tRNA ligase, cytoplasmic, ... | Authors: | Kim, S, Son, J, Kim, S, Hwang, K.Y. | Deposit date: | 2019-08-20 | Release date: | 2021-01-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. Cell Rep, 35, 2021
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