6M88
| Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with myricetin | Descriptor: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Inositol polyphosphate multikinase,Inositol polyphosphate multikinase | Authors: | Wang, H, Shears, S.B. | Deposit date: | 2018-08-21 | Release date: | 2019-01-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis. J. Med. Chem., 62, 2019
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3V93
| unliganded structure of TcrPDEC1 catalytic domain | Descriptor: | Cyclic nucleotide specific phosphodiesterase, MAGNESIUM ION, ZINC ION | Authors: | Wang, H, Kunz, S, Chen, G, Seebeck, T, Wan, Y, Robinson, H, Martinelli, S, Ke, H. | Deposit date: | 2011-12-23 | Release date: | 2012-02-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biological and structural characterization of Trypanosoma cruzi phosphodiesterase C and Implications for design of parasite selective inhibitors. J.Biol.Chem., 287, 2012
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3V94
| TcrPDEC1 catalytic domain in complex with inhibitor wyq16 | Descriptor: | Cyclic nucleotide specific phosphodiesterase, MAGNESIUM ION, ZINC ION, ... | Authors: | Wang, H, Kunz, S, Chen, G, Seebeck, T, Wan, Y, Robinson, H, Martinelli, S, Ke, H. | Deposit date: | 2011-12-23 | Release date: | 2012-02-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | TcrPDEC1 catalytic domain in complex with inhibitor wyq16 To be Published
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3O47
| Crystal structure of ARFGAP1-ARF1 fusion protein | Descriptor: | ADP-ribosylation factor GTPase-activating protein 1, ADP-ribosylation factor 1, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Wang, H, Tong, Y, Nedyalkova, L, Tempel, W, Guan, X, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-07-26 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of ARFGAP1-ARF1 fusion protein to be published
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7MOH
| Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 5-diphosphoinositol 1,3,4,6-tetrakisphosphate (5PP-InsP4) and phosphate in conformation B (Pi(B)) | Descriptor: | (1r,2R,3S,4r,5R,6S)-4-hydroxy-2,3,5,6-tetrakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, PHOSPHATE ION, Tyrosine-protein phosphatase DSP1 | Authors: | Wang, H, Shears, S.B. | Deposit date: | 2021-05-01 | Release date: | 2022-03-02 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
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7MOK
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7MOF
| Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 6-diphosphoinositol 1,2,3,4,5-pentakisphosphate 6-InsP7 | Descriptor: | (1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, INOSITOL HEXAKISPHOSPHATE, Tyrosine-protein phosphatase DSP1 | Authors: | Wang, H, Shears, S.B. | Deposit date: | 2021-05-01 | Release date: | 2022-03-02 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
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7MOI
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7MOJ
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7MOM
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7MOD
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7MOG
| Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 5-PCF2 Am-InsP5, an analogue of 5-InsP7 | Descriptor: | (1,1-difluoro-2-oxo-2-{[(1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]amino}ethyl)phosphonic acid, Tyrosine-protein phosphatase DSP1 | Authors: | Wang, H, Shears, S.B. | Deposit date: | 2021-05-01 | Release date: | 2022-03-02 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
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7MOL
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7MOE
| Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1)Cys150Ser in complex with 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate (5-InsP7) | Descriptor: | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, Tyrosine-protein phosphatase DSP1 | Authors: | Wang, H, Shears, S.B. | Deposit date: | 2021-05-01 | Release date: | 2022-03-02 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13, 2022
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5Z3W
| Malate dehydrogenase binds silver at C113 | Descriptor: | Malate dehydrogenase, SILVER ION | Authors: | Wang, H, Wang, M, Sun, H. | Deposit date: | 2018-01-09 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Atomic differentiation of silver binding preference in protein targets: Escherichia coli malate dehydrogenase as a paradigm Chem Sci, 2020
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7OHA
| nucleosome with TBP and TFIIA bound at SHL +2 | Descriptor: | DNA (122-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Wang, H, Cramer, P. | Deposit date: | 2021-05-09 | Release date: | 2021-07-28 | Last modified: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures and implications of TBP-nucleosome complexes. Proc.Natl.Acad.Sci.USA, 118, 2021
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7OH9
| Nucleosome with TBP and TFIIA bound at SHL -6 | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Wang, H, Cramer, P. | Deposit date: | 2021-05-09 | Release date: | 2021-07-28 | Last modified: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures and implications of TBP-nucleosome complexes. Proc.Natl.Acad.Sci.USA, 118, 2021
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7OHB
| TBP-nucleosome complex | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Wang, H, Cramer, P. | Deposit date: | 2021-05-10 | Release date: | 2021-07-28 | Last modified: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures and implications of TBP-nucleosome complexes. Proc.Natl.Acad.Sci.USA, 118, 2021
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7OHC
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1WDT
| Crystal structure of ttk003000868 from Thermus thermophilus HB8 | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, elongation factor G homolog | Authors: | Wang, H, Takemoto-Hori, C, Murayama, K, Sekine, S, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-17 | Release date: | 2005-05-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of ttk003000868 from Thermus thermophilus HB8 To be published
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1WWP
| Crystal structure of ttk003001694 from Thermus Thermophilus HB8 | Descriptor: | hypothetical protein TTHA0636 | Authors: | Wang, H, Murayama, K, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-01-12 | Release date: | 2005-07-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Crystal structure of ttk003001694 from Thermus Thermophilus HB8 TO BE PUBLISHED
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1BM5
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6IO6
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3HBT
| The structure of native G-actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, CALCIUM ION, ... | Authors: | Wang, H, Robinson, R.C, Burtnick, L.D. | Deposit date: | 2009-05-05 | Release date: | 2010-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structure of native G-actin Cytoskeleton (Hoboken), 67, 2010
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4QBS
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