2YV6

Crystal structure of human Bcl-2 family protein Bak

Summary for 2YV6

Entry DOI	10.2210/pdb2yv6/pdb
Descriptor	Bcl-2 homologous antagonist/killer, SULFATE ION (3 entities in total)
Functional Keywords	structure genomics, bcl domain, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, apoptosis
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion membrane; Single-pass membrane protein (Potential): Q16611
Total number of polymer chains	1
Total formula weight	18737.33
Authors	Wang, H.,Kishishita, S.,Murayama, K.,Takemoto, C.,Terada, T.,Shirouzu, M.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2007-04-09, release date: 2008-04-15, Last modification date: 2011-07-13)
Primary citation	Wang, H.,Takemoto, C.,Akasaka, R.,Uchikubo-Kamo, T.,Kishishita, S.,Murayama, K.,Terada, T.,Chen, L.,Liu, Z.J.,Wang, B.C.,Sugano, S.,Tanaka, A.,Inoue, M.,Kigawa, T.,Shirouzu, M.,Yokoyama, S. Novel dimerization mode of the human Bcl-2 family protein Bak, a mitochondrial apoptosis regulator. J.Struct.Biol., 166:32-37, 2009 Cited by PubMed: 19135534 DOI: 10.1016/j.jsb.2008.12.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation