4MMD

Crystal structure of LeuBAT (delta6 mutant) in complex with (S)-duloxetine

Summary for 4MMD

Entry DOI	10.2210/pdb4mmd/pdb
Related	4MM4 4MM5 4MM6 4MM7 4MM8 4MM9 4MMA 4MMB 4MMC 4MME 4MMF
Descriptor	Transporter, SODIUM ION, (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, ... (5 entities in total)
Functional Keywords	transporter, transport protein
Biological source	Aquifex aeolicus
Total number of polymer chains	2
Total formula weight	117700.68
Authors	Wang, H.,Gouaux, E. (deposition date: 2013-09-08, release date: 2013-10-16, Last modification date: 2024-02-28)
Primary citation	Wang, H.,Goehring, A.,Wang, K.H.,Penmatsa, A.,Ressler, R.,Gouaux, E. Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503:141-145, 2013 Cited by PubMed: 24121440 DOI: 10.1038/nature12648 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation