4ZYO

Crystal Structure of Human Integral Membrane Stearoyl-CoA Desaturase with Substrate

Summary for 4ZYO

Entry DOI	10.2210/pdb4zyo/pdb
Descriptor	Acyl-CoA desaturase, ZINC ION, STEAROYL-COENZYME A, ... (5 entities in total)
Functional Keywords	membrane protein, desaturase, metal binding protein, oxidoreductase
Biological source	Homo sapiens (Human)
Cellular location	Endoplasmic reticulum membrane ; Multi-pass membrane protein : O00767
Total number of polymer chains	1
Total formula weight	38473.64
Authors	Wang, H.,Klein, M.G.,Lane, W.,Snell, G.,Levin, I.,Li, K.,Zou, H.,Sang, B.-C. (deposition date: 2015-05-21, release date: 2015-06-17, Last modification date: 2024-03-06)
Primary citation	Wang, H.,Klein, M.G.,Zou, H.,Lane, W.,Snell, G.,Levin, I.,Li, K.,Sang, B.C. Crystal structure of human stearoyl-coenzyme A desaturase in complex with substrate. Nat.Struct.Mol.Biol., 22:581-585, 2015 Cited by PubMed: 26098317 DOI: 10.1038/nsmb.3049 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.25 Å)

Structure validation