4ZYO
Crystal Structure of Human Integral Membrane Stearoyl-CoA Desaturase with Substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Acyl-CoA desaturase | polymer | 318 | 36798.2 | 1 | UniProt (O00767) | Homo sapiens (Human) | Delta(9)-desaturase,Delta-9 desaturase,Fatty acid desaturase,Stearoyl-CoA desaturase |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | STEAROYL-COENZYME A | non-polymer | 1034.0 | 1 | Chemie (ST9) | |||
| 4 | E (A) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) | |||
| 5 | F (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 45 - 359 (UniProt: O00767)
| PDB | External Database | Details |
|---|---|---|
| Gly 42 | - | expression tag |
| Gly 43 | - | expression tag |
| Ser 44 | - | expression tag |
| Ala 60 | Lys 60 | engineered mutation |
| Ala 62 | Lys 62 | engineered mutation |
| Ala 63 | Glu 63 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36798.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1675.4 | |
| All* | Total formula weight | 38473.6 |
