3NV6
 
 | | Crystal Structure of Camphor-Bound CYP101D2 | | Descriptor: | CAMPHOR, Cytochrome P450, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Yang, W, Bell, S.G, Wang, H, Zhou, W.H, Bartlam, M, Wong, L.L, Rao, Z. | | Deposit date: | 2010-07-08 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structure of CYP101D2 unveils a potential path for substrate entry into the active site
Biochem.J., 433, 2011
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5GW4
 | | Structure of Yeast NPP-TRiC | | Descriptor: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | | Authors: | Zang, Y, Jin, M, Wang, H, Cong, Y. | | Deposit date: | 2016-09-08 | | Release date: | 2016-10-26 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM.
Nat. Struct. Mol. Biol., 23, 2016
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3OH8
 | | Crystal structure of the nucleoside-diphosphate sugar epimerase from Corynebacterium glutamicum. Northeast Structural Genomics Consortium Target CgR91 | | Descriptor: | Nucleoside-diphosphate sugar epimerase (SulA family) | | Authors: | Vorobiev, S, Lew, S, Kuzin, A, Mao, M, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-08-17 | | Release date: | 2010-09-01 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.997 Å) | | Cite: | Crystal structure of the nucleoside-diphosphate sugar epimerase from Corynebacterium glutamicum. Northeast Structural Genomics Consortium Target CgR91.
To be Published
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5GW5
 | | Structure of TRiC-AMP-PNP | | Descriptor: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | | Authors: | Zang, Y, Jin, M, Wang, H, Cong, Y. | | Deposit date: | 2016-09-08 | | Release date: | 2016-10-26 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM.
Nat. Struct. Mol. Biol., 23, 2016
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3P9V
 | | High Resolution Crystal Structure of protein Maqu_3174 from Marinobacter aquaeolei, Northeast Structural Genomics Consortium Target MqR197 | | Descriptor: | Uncharacterized protein | | Authors: | Kuzin, A, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-10-18 | | Release date: | 2010-10-27 | | Last modified: | 2012-02-22 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Northeast Structural Genomics Consortium Target MqR197
To be published
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3LXI
 | | Crystal Structure of Camphor-Bound CYP101D1 | | Descriptor: | CAMPHOR, Cytochrome P450, PHOSPHATE ION, ... | | Authors: | Yang, W, Bell, S.G, Wang, H, Bartlam, M, Wong, L.L, Rao, Z. | | Deposit date: | 2010-02-25 | | Release date: | 2010-06-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444
J.Biol.Chem., 285, 2010
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3P3Q
 | | Crystal Structure of MmoQ Response regulator from Methylococcus capsulatus str. Bath at the resolution 2.4A, Northeast Structural Genomics Consortium Target McR175M | | Descriptor: | MmoQ, SODIUM ION, SULFATE ION | | Authors: | Kuzin, A.P, Vorobiev, S.M, Abashidze, M, Seetharaman, J, Janjua, J, Xiao, R, Foote, E.L, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-10-05 | | Release date: | 2010-11-10 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Northeast Structural Genomics Consortium Target McR175M
To be Published
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2QC3
 | | Crystal structure of MCAT from Mycobacterium tuberculosis | | Descriptor: | ACETIC ACID, Malonyl CoA-acyl carrier protein transacylase | | Authors: | Li, Z, Huang, Y, Ge, J, Bartlam, M, Wang, H, Rao, Z. | | Deposit date: | 2007-06-19 | | Release date: | 2007-08-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Crystal Structure of MCAT from Mycobacterium tuberculosis Reveals Three New Catalytic Models.
J.Mol.Biol., 371, 2007
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8HLL
 | | Crystal structure of p53/BCL2 fusion complex (complex 1) | | Descriptor: | Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION | | Authors: | Wei, H, Guo, M, Wang, H, Chen, Y. | | Deposit date: | 2022-11-30 | | Release date: | 2023-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.
Nat Commun, 14, 2023
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8HLM
 | | Crystal structure of p53/BCL2 fusion complex (complex 2) | | Descriptor: | Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION | | Authors: | Guo, M, Wang, H, Wei, H, Chen, Y. | | Deposit date: | 2022-11-30 | | Release date: | 2023-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.522 Å) | | Cite: | Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.
Nat Commun, 14, 2023
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8HLN
 | | Crystal structure of p53/BCL2 fusion complex(complex3) | | Descriptor: | Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION | | Authors: | Guo, M, Wei, H, Wang, H, Chen, Y. | | Deposit date: | 2022-11-30 | | Release date: | 2023-07-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.354 Å) | | Cite: | Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.
Nat Commun, 14, 2023
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3IGN
 | | Crystal Structure of the GGDEF domain from Marinobacter aquaeolei diguanylate cyclase complexed with c-di-GMP - Northeast Structural Genomics Consortium Target MqR89a | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Diguanylate cyclase | | Authors: | Vorobiev, S, Neely, H, Seetharaman, J, Wang, H, Foote, E.L, Ciccosanti, C, Sahdev, S, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-07-28 | | Release date: | 2009-08-11 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Crystal structure of a catalytically active GG(D/E)EF diguanylate cyclase domain from Marinobacter aquaeolei with bound c-di-GMP product.
J.Struct.Funct.Genom., 13, 2012
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2KCT
 | | Solution nmr structure of the ob-fold domain of heme chaperone ccme from desulfovibrio vulgaris. northeast structural genomics target dvr115g. | | Descriptor: | Cytochrome c-type biogenesis protein CcmE | | Authors: | Aramini, J.M, Rossi, P, Lee, H, Lemak, A, Wang, H, Foote, E.L, Jiang, M, Xiao, R, Nair, R, Swapna, G.V.T, Acton, T.B, Rost, B, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-12-29 | | Release date: | 2009-02-10 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution nmr structure of the ob-fold domain of heme chaperone
ccme from desulfovibrio vulgaris. northeast structural genomics target dvr115g.
To be Published
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2KS0
 | | Solution NMR structure of the Q251Q8_DESHY(21-82) protein from Desulfitobacterium Hafniense, Northeast Structural Genomics Consortium Target DhR8C | | Descriptor: | Uncharacterized protein | | Authors: | Yang, Y, Ramelot, T.A, Cort, J.R, Wang, H, Ciccosanti, C, Foote, E.L, Jiang, M, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-12-23 | | Release date: | 2010-01-12 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Combining NMR and EPR methods for homodimer protein structure determination.
J.Am.Chem.Soc., 132, 2010
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2KO1
 | | Solution NMR structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum. Northeast Structural Genomics Consortium Target CtR148A | | Descriptor: | GTP pyrophosphokinase | | Authors: | Eletsky, A, Garcia, E, Wang, H, Ciccosanti, C, Jiang, M, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Lee, H, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-09-08 | | Release date: | 2009-09-29 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum
To be Published
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2KYI
 | | Solution NMR structure of Dsy0195(21-82) protein from Desulfitobacterium Hafniense. Northeast Structural Genomics Consortium Target DhR8C | | Descriptor: | Uncharacterized protein | | Authors: | Yang, Y, Ramelot, T.A, Cort, J.R, Wang, H, Ciccosanti, C, Foote, E.L, Jiang, M, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-05-27 | | Release date: | 2010-06-09 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Combining NMR and EPR methods for homodimer protein structure determination.
J.Am.Chem.Soc., 132, 2010
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2KYW
 | | Solution NMR Structure of a domain of adhesion exoprotein from Pediococcus pentosaceus, Northeast Structural Genomics Consortium Target PtR41O | | Descriptor: | Adhesion exoprotein | | Authors: | He, Y, Eletsky, A, Mills, J.L, Wang, H, Ciccosanti, C, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Lee, H.-W, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-06-09 | | Release date: | 2010-08-04 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of a domain of adhesion exoprotein from Pediococcus pentosaceus, Northeast Structural Genomics Consortium Target PtR41O
To be Published
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2JVM
 | | Solution NMR structure of Rhodobacter sphaeroides protein RHOS4_26430. Northeast Structural Genomics Consortium target RhR95 | | Descriptor: | Uncharacterized protein | | Authors: | Eletsky, A, Sukumaran, D, Zhang, Q, Parish, D, Xu, D, Wang, H, Janjua, H, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-09-21 | | Release date: | 2007-10-16 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of Rhodobacter sphaeroides protein RHOS4_26430.
To be Published
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2LFC
 | | Solution NMR Structure of Fumarate reductase flavoprotein subunit from Lactobacillus plantarum, Northeast Structural Genomics Consortium Target LpR145J | | Descriptor: | Fumarate reductase, flavoprotein subunit | | Authors: | Liu, G, Tang, Y, Xiao, R, Janjua, H, Ciccosanti, C, Wang, H, Acton, T, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-06-29 | | Release date: | 2011-08-17 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Northeast Structural Genomics Consortium Target LpR145J
To be Published
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4KAA
 | | Crystal structure of the halotag2 protein at the resolution 2.3A, Northeast Structural Genomics Consortium (NESG) target OR150 | | Descriptor: | DI(HYDROXYETHYL)ETHER, Haloalkane dehalogenase, SODIUM ION | | Authors: | Kuzin, A, Lew, S, Neklesa, T.K, Noblin, D, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, H, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Crews, C, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-04-22 | | Release date: | 2013-06-05 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.276 Å) | | Cite: | Northeast Structural Genomics Consortium Target OR150
To be Published
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4KAJ
 | | X-Ray Structure of the complex of Haloalkane dehalogenase HaloTag7 with HALTS, Northeast Structural Genomics Consortium (NESG) Target OR151 | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, MANGANESE (II) ION, ... | | Authors: | Kuzin, A, Lew, S, Neklesa, T.K, Noblin, D, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, H, Everett, J.K, Acton, T.B, Kornhaber, G, Montelione, G.T, Crews, C.M, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-04-22 | | Release date: | 2013-06-05 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.948 Å) | | Cite: | Northeast Structural Genomics Consortium Target OR151
To be Published
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4KYV
 | | Crystal Structure of dehalogenase HaloTag2 with HALTS at the resolution 1.8A. Northeast Structural Genomics Consortium (NESG) Target OR150 | | Descriptor: | N-(2-ethoxy-3,5-dimethylbenzyl)-1H-tetrazol-5-amine, SODIUM ION, dehalogenase HaloTag2 | | Authors: | Kuzin, A, Lew, S, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, H, Everett, J.K, Acton, T.B, Kornhaber, G, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-05-29 | | Release date: | 2013-07-24 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.796 Å) | | Cite: | Northeast Structural Genomics Consortium Target OR150
To be Published
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4L6E
 | | Crystal Structure of the RanBD1 fourth domain of E3 SUMO-protein ligase RanBP2. Northeast Structural Genomics Consortium (NESG) Target HR9193b | | Descriptor: | E3 SUMO-protein ligase RanBP2 | | Authors: | Vorobiev, S, Su, M, Seetharaman, J, Mao, L, Xiao, R, Maglaqui, M, Kogan, S, Wang, H, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-06-12 | | Release date: | 2013-06-26 | | Method: | X-RAY DIFFRACTION (2.496 Å) | | Cite: | Crystal Structure of the RanBD1 fourth domain of E3 SUMO-protein ligase RanBP2.
To be Published
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3RRU
 | | X-ray crystal structure of the VHS domain of human TOM1-like protein, Northeast Structural Genomics Consortium Target HR3050E | | Descriptor: | TOM1L1 protein | | Authors: | Forouhar, F, Lew, S, Seetharaman, J, Wang, H, Ciccosanti, C, Patel, D, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-04-30 | | Release date: | 2011-06-08 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray crystal structure of the VHS domain of human TOM1-like protein, Northeast Structural Genomics Consortium Target HR3050E
To be Published
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3SZ5
 | | Crystal Structure of LHK-Exo in complex with 5-phosphorylated oligothymidine (dT)4 | | Descriptor: | 5'-D(P*TP*TP*TP*T)-3', Exonuclease, MAGNESIUM ION | | Authors: | Yang, W, Chen, W.Y, Wang, H, Zhang, Q, Zhou, W, Bartlam, M, Watt, R.M, Rao, Z. | | Deposit date: | 2011-07-18 | | Release date: | 2012-02-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis.
Nucleic Acids Res., 39, 2011
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