8HLN
Crystal structure of p53/BCL2 fusion complex(complex3)
Summary for 8HLN
Entry DOI | 10.2210/pdb8hln/pdb |
Descriptor | Cellular tumor antigen p53, Apoptosis regulator Bcl-2, ZINC ION, ... (4 entities in total) |
Functional Keywords | bcl-2, p53, apoptosis |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 41784.90 |
Authors | |
Primary citation | Wei, H.,Wang, H.,Wang, G.,Qu, L.,Jiang, L.,Dai, S.,Chen, X.,Zhang, Y.,Chen, Z.,Li, Y.,Guo, M.,Chen, Y. Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity. Nat Commun, 14:4300-4300, 2023 Cited by PubMed: 37463921DOI: 10.1038/s41467-023-40087-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.354 Å) |
Structure validation
Download full validation report