1Q2U
| Crystal structure of DJ-1/RS and implication on familial Parkinson's disease | 分子名称: | RNA-binding protein regulatory subunit | 著者 | Huai, Q, Sun, Y, Wang, H, Chin, L.S, Li, L, Robinson, H, Ke, H. | 登録日 | 2003-07-26 | 公開日 | 2003-10-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of DJ-1/RS and implication on familial Parkinson's disease Febs Lett., 549, 2003
|
|
1Q9M
| Three dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity | 分子名称: | ROLIPRAM, ZINC ION, cAMP-specific phosphodiesterase PDE4D2 | 著者 | Huai, Q, Wang, H, Sun, Y, Kim, H.Y, Liu, Y, Ke, H. | 登録日 | 2003-08-25 | 公開日 | 2003-09-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Three dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity Structure, 11, 2003
|
|
1OYN
| Crystal structure of PDE4D2 in complex with (R,S)-rolipram | 分子名称: | ROLIPRAM, ZINC ION, cAMP-specific phosphodiesterase PDE4D2 | 著者 | Huai, Q, Wang, H, Sun, Y, Kim, H.Y, Liu, Y, Ke, H. | 登録日 | 2003-04-05 | 公開日 | 2003-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity Structure, 11, 2003
|
|
3GAD
| Structure of apomif | 分子名称: | ACETIC ACID, Macrophage migration inhibitory factor-like protein, SULFATE ION | 著者 | Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. | 登録日 | 2009-02-17 | 公開日 | 2009-12-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host Mol.Immunol., 47, 2010
|
|
3GAC
| Structure of mif with HPP | 分子名称: | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ACETIC ACID, Macrophage migration inhibitory factor-like protein, ... | 著者 | Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. | 登録日 | 2009-02-17 | 公開日 | 2009-12-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host Mol.Immunol., 47, 2010
|
|
4JQ0
| Voltage-gated sodium channel 1.5 C-terminal domain in complex with FGF12B and Ca2+/calmodulin | 分子名称: | CALCIUM ION, Calmodulin, Fibroblast growth factor 12, ... | 著者 | Wang, C, Chung, B.C, Yan, H, Wang, H.G, Lee, S.Y, Pitt, G.S. | 登録日 | 2013-03-19 | 公開日 | 2014-05-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.84 Å) | 主引用文献 | Structural analyses of Ca(2+)/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation. Nat Commun, 5, 2014
|
|
7SBF
| PZM21 bound Mu Opioid Receptor-Gi Protein Complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Huang, W, Qu, Q, Wang, H, Skiniotis, G, Kobilka, B. | 登録日 | 2021-09-24 | 公開日 | 2022-04-20 | 最終更新日 | 2022-07-06 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure-Based Evolution of G Protein-Biased mu-Opioid Receptor Agonists. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
6J6I
| Reconstitution and structure of a plant NLR resistosome conferring immunity | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Disease resistance RPP13-like protein 4, Probable serine/threonine-protein kinase PBL2, ... | 著者 | Wang, J.Z, Wang, J, Hu, M.J, Wang, H.W, Zhou, J.M, Chai, J.J. | 登録日 | 2019-01-15 | 公開日 | 2019-03-20 | 最終更新日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Reconstitution and structure of a plant NLR resistosome conferring immunity. Science, 364, 2019
|
|
6J5U
| Ligand-triggered allosteric ADP release primes a plant NLR complex | 分子名称: | Disease resistance RPP13-like protein 4, Probable serine/threonine-protein kinase PBL2, Protein kinase superfamily protein, ... | 著者 | Wang, J.Z, Wang, J, Meijuan, H, Wang, H.W, Zhou, J.M, Chai, J.J. | 登録日 | 2019-01-12 | 公開日 | 2019-04-03 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Ligand-triggered allosteric ADP release primes a plant NLR complex. Science, 364, 2019
|
|
1BC9
| CYTOHESIN-1/B2-1 SEC7 DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | CYTOHESIN-1 | 著者 | Betz, S.F, Schnuchel, A, Wang, H, Olejniczak, E.T, Meadows, R.P, Fesik, S.W. | 登録日 | 1998-05-06 | 公開日 | 1999-05-11 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the cytohesin-1 (B2-1) Sec7 domain and its interaction with the GTPase ADP ribosylation factor 1. Proc.Natl.Acad.Sci.USA, 95, 1998
|
|
4RA2
| PP2Ca | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, Protein phosphatase 1A | 著者 | Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. | 登録日 | 2014-09-09 | 公開日 | 2015-05-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | The catalytic role of the M2 metal ion in PP2Ca SCI REP, 2015
|
|
4RAG
| CRYSTAL STRUCTURE of PPC2A-D38K | 分子名称: | MANGANESE (II) ION, Protein phosphatase 1A | 著者 | Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. | 登録日 | 2014-09-10 | 公開日 | 2015-08-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The catalytic role of the M2 metal ion in PP2C alpha Sci Rep, 5, 2015
|
|
4RAF
| Crystal structure of PP2Ca-D38A | 分子名称: | MANGANESE (II) ION, Protein phosphatase 1A | 著者 | Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. | 登録日 | 2014-09-10 | 公開日 | 2015-08-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | The catalytic role of the M2 metal ion in PP2C alpha Sci Rep, 5, 2015
|
|
4F7T
| Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PB1 (498-505) | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | 著者 | Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F. | 登録日 | 2012-05-16 | 公開日 | 2012-10-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals. J.Virol., 86, 2012
|
|
1CKR
| HIGH RESOLUTION SOLUTION STRUCTURE OF THE HEAT SHOCK COGNATE-70 KD SUBSTRATE BINDING DOMAIN OBTAINED BY MULTIDIMENSIONAL NMR TECHNIQUES | 分子名称: | HEAT SHOCK SUBSTRATE BINDING DOMAIN OF HSC-70 | 著者 | Morshauser, R.C, Hu, W, Wang, H, Pang, Y, Flynn, G.C, Zuiderweg, E.R.P. | 登録日 | 1999-04-22 | 公開日 | 1999-04-30 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | High-resolution solution structure of the 18 kDa substrate-binding domain of the mammalian chaperone protein Hsc70. J.Mol.Biol., 289, 1999
|
|
2FH3
| C-terminal half of gelsolin soaked in low calcium at pH 8 | 分子名称: | CALCIUM ION, Gelsolin | 著者 | Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C. | 登録日 | 2005-12-23 | 公開日 | 2006-06-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Calcium ion exchange in crystalline gelsolin J.Mol.Biol., 357, 2006
|
|
2FH2
| C-terminal half of gelsolin soaked in EGTA at pH 4.5 | 分子名称: | CALCIUM ION, Gelsolin | 著者 | Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C. | 登録日 | 2005-12-23 | 公開日 | 2006-06-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Calcium ion exchange in crystalline gelsolin J.Mol.Biol., 357, 2006
|
|
2RBL
| |
2RB8
| |
3W94
| |
7T2G
| CryoEM structure of mu-opioid receptor - Gi protein complex bound to mitragynine pseudoindoxyl (MP) | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Seven, A.B, Qu, Q, Robertson, M.J, Wang, H, Kobilka, B.K, Skiniotis, G. | 登録日 | 2021-12-04 | 公開日 | 2022-12-07 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Insights into distinct signaling profiles of the mu OR activated by diverse agonists. Nat.Chem.Biol., 2022
|
|
5ZAK
| Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | 登録日 | 2018-02-07 | 公開日 | 2018-05-09 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
|
|
3KH0
| Crystal structure of the Ras-association (RA) domain of RALGDS | 分子名称: | Ral guanine nucleotide dissociation stimulator, UNKNOWN ATOM OR ION | 著者 | Shen, Y, Tempel, W, Wang, H, Tong, Y, Guan, X, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2009-10-29 | 公開日 | 2009-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the Ras-association (RA) domain of RALGDS to be published
|
|
2A4G
| Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound | 分子名称: | ({1-[1-CARBAMOYL-PHENYL-METHYL)-CARBAMOYL]-METHYL}-AMINOOXALYL)-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL)-CYCLOHEXYL-METHYL)-CARBAMIC ACID ISOBUTYL ESTER, NS3 protease/helicase, NS4a peptide, ... | 著者 | Arasappan, A, Njoroge, F.G, Chan, T.Y, Bennett, F, Bogen, S.L, Chen, K, Gu, H, Hong, L, Jao, E, Liu, Y.T, Lovey, R.G, Parekh, T, Pike, R.E, Pinto, P, Santhanam, B, Venkatraman, S, Vaccaro, H, Wang, H, Yang, X, Zhu, Z, Mckittrick, B, Saksena, A.K, Girijavallabhan, V, Pichardo, J, Butkiewicz, N, Ingram, R, Malcolm, B, Prongay, A.J, Yao, N, Marten, B, Madison, V, Kemp, S, Levy, O, Lim-Wilby, M, Tamura, S, Ganguly, A.K. | 登録日 | 2005-06-28 | 公開日 | 2006-07-04 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Hepatitis C virus NS3-4a serine protease inhibitors. SAR of P2' moiety with improved potency. Bioorg.Med.Chem.Lett., 15, 2005
|
|
1LP9
| Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Buslepp, J, Wang, H, Biddison, W.E, Appella, E, Collins, E.J. | 登録日 | 2002-05-07 | 公開日 | 2003-11-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection. Immunity, 19, 2003
|
|