1Q9M

Three dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity

Replaces:  1OYM

Summary for 1Q9M

• Entry DOI: 10.2210/pdb1q9m/pdb
• Descriptor: cAMP-specific phosphodiesterase PDE4D2, ZINC ION, ROLIPRAM, ... (4 entities in total)
• Functional Keywords: pde, rolipram, specific inhibitor, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm (By similarity): Q08499
• Total number of polymer chains: 4
• Total formula weight: 167203.74

Authors

Huai, Q.,Wang, H.,Sun, Y.,Kim, H.Y.,Liu, Y.,Ke, H. (deposition date: 2003-08-25, release date: 2003-09-02, Last modification date: 2024-04-03)

• Primary citation: Huai, Q.,Wang, H.,Sun, Y.,Kim, H.Y.,Liu, Y.,Ke, H.; Three dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity; Structure, 11:865-873, 2003; PubMed: 12842049; DOI: 10.1016/S0969-2126(03)00123-0

Experimental method

X-RAY DIFFRACTION (2.3 Å)