Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 1075 results

4J1R
DownloadVisualize
BU of 4j1r by Molmil
Crystal Structure of GSK3b in complex with inhibitor 15R
Descriptor: (2R)-2-(1H-indol-3-ylmethyl)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, Glycogen synthase kinase-3 beta, PHOSPHATE ION, ...
Authors:Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-02-01
Release date:2013-03-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
6J76
DownloadVisualize
BU of 6j76 by Molmil
Structure of 3,6-anhydro-L-galactose Dehydrogenase in Complex with NAP
Descriptor: Aldehyde dehydrogenase A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Li, P.Y, Wang, Y, Chen, X.L, Zhang, Y.Z.
Deposit date:2019-01-17
Release date:2020-01-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.368 Å)
Cite:3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
J.Mol.Biol., 432, 2020
5EZK
DownloadVisualize
BU of 5ezk by Molmil
RNA polymerase model placed by Molecular replacement into X-ray diffraction map of DNA-bound RNA Polymerase-Sigma 54 holoenzyme complex.
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Darbari, V.C, Yang, Y, Lu, D, Zhang, N, Glyde, R, Wang, Y, Murakami, K.S, Buck, M, Zhang, X.
Deposit date:2015-11-26
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (8.5 Å)
Cite:TRANSCRIPTION. Structures of the RNA polymerase- Sigma 54 reveal new and conserved regulatory strategies.
Science, 349, 2015
4LEJ
DownloadVisualize
BU of 4lej by Molmil
Crystal Structure of the Korean pine (Pinus koraiensis) vicilin
Descriptor: COPPER (II) ION, GLYCEROL, PHOSPHATE ION, ...
Authors:Jin, T.C, Wang, Y, Zhang, Y.Z.
Deposit date:2013-06-25
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Crystal Structure of Korean Pine ( Pinus koraiensis ) 7S Seed Storage Protein with Copper Ligands.
J.Agric.Food Chem., 62, 2014
3CIY
DownloadVisualize
BU of 3ciy by Molmil
Mouse Toll-like receptor 3 ectodomain complexed with double-stranded RNA
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Liu, L, Botos, I, Wang, Y, Leonard, J.N, Shiloach, J, Segal, D.M, Davies, D.R.
Deposit date:2008-03-12
Release date:2008-05-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008
6J75
DownloadVisualize
BU of 6j75 by Molmil
Structure of 3,6-anhydro-L-galactose Dehydrogenase
Descriptor: Aldehyde dehydrogenase A
Authors:Li, P.Y, Wang, Y, Chen, X.L, Zhang, Y.Z.
Deposit date:2019-01-17
Release date:2020-01-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.695 Å)
Cite:3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
J.Mol.Biol., 432, 2020
6AX3
DownloadVisualize
BU of 6ax3 by Molmil
Complex structure of JMJD5 and Symmetric Dimethyl-Arginine (SDMA)
Descriptor: 2-OXOGLUTARIC ACID, Lysine-specific demethylase 8, N3, ...
Authors:Lee, S, Liu, H, Wang, Y, Dai, S, Zhang, G.
Deposit date:2017-09-06
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
Sci Rep, 8, 2018
1WMS
DownloadVisualize
BU of 1wms by Molmil
High resolution crystal structure of human Rab9 GTPase: a novel antiviral drug target
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-9A
Authors:Chen, L, DiGiammarino, E, Zhou, X.E, Wang, Y, Toh, D, Hodge, T.W, Meehan, E.J.
Deposit date:2004-07-16
Release date:2004-09-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:High resolution crystal structure of human Rab9 GTPase: A novel antiviral drug target
J.Biol.Chem., 279, 2004
1X6L
DownloadVisualize
BU of 1x6l by Molmil
Crystal structure of S. marcescens chitinase A mutant W167A
Descriptor: Chitinase A
Authors:Aronson Jr, N.N, Halloran, B.A, Alexyev, M.F, Zhou, X.E, Wang, Y, Meehan, E.J, Chen, L.
Deposit date:2004-08-11
Release date:2005-07-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mutation of Trp167 at the -3 subsite of the chitin-binding cleft of S. marcescens chitinase A caused enhanced transglycosylation
To be Published
6K3B
DownloadVisualize
BU of 6k3b by Molmil
Crystal structure of Lpg2147-Lpg2149 complex
Descriptor: Lpg2147, Uncharacterized protein
Authors:Mu, Y, Wang, Y, Han, Y, Li, D, Feng, Y.
Deposit date:2019-05-17
Release date:2020-04-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.974 Å)
Cite:Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
3CIG
DownloadVisualize
BU of 3cig by Molmil
Crystal structure of mouse TLR3 ectodomain
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Liu, L, Botos, I, Wang, Y, Leonard, J.N, Shiloach, J, Segal, D.M, Davies, D.R.
Deposit date:2008-03-11
Release date:2008-05-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008
8TG1
DownloadVisualize
BU of 8tg1 by Molmil
Caldicellulosiruptor saccharolyticus periplasmic urea-binding protein
Descriptor: BROMIDE ION, Extracellular ligand-binding receptor, UREA
Authors:Allert, M.J, Kumar, S, Wang, Y, Beese, L.S, Hellinga, H.W.
Deposit date:2023-07-12
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Structure-based functional analysis reveals multiple roles and widespread use of urea-binding proteins in nitrogen metabolism
To Be Published
4J71
DownloadVisualize
BU of 4j71 by Molmil
Crystal Structure of GSK3b in complex with inhibitor 1R
Descriptor: (2R)-2-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, CHLORIDE ION, Glycogen synthase kinase-3 beta, ...
Authors:Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-02-12
Release date:2013-03-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
6AVS
DownloadVisualize
BU of 6avs by Molmil
Complex structure of JMJD5 and Symmetric Monomethyl-Arginine (MMA)
Descriptor: (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, Lysine-specific demethylase 8, ZINC ION
Authors:Lee, S, Liu, H, Wang, Y, Dai, S, Zhang, G.
Deposit date:2017-09-04
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
Sci Rep, 8, 2018
4R0S
DownloadVisualize
BU of 4r0s by Molmil
Crystal structure of P. aeruginosa TpbA
Descriptor: GLYCEROL, PHOSPHATE ION, Protein tyrosine phosphatase TpbA
Authors:Xu, K, Li, S, Wang, Y, Bartlam, M.
Deposit date:2014-08-01
Release date:2015-05-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1
PLoS ONE, 10, 2015
3CPU
DownloadVisualize
BU of 3cpu by Molmil
SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT
Descriptor: CALCIUM ION, CHLORIDE ION, Pancreatic alpha-amylase, ...
Authors:Brayer, G.D, Sidhu, G, Maurus, R, Rydberg, E.H, Braun, C, Wang, Y, Nguyen, N.T, Overall, C.M, Withers, S.G.
Deposit date:1999-06-08
Release date:2001-06-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques.
Biochemistry, 39, 2000
8JFQ
DownloadVisualize
BU of 8jfq by Molmil
Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-back Loop
Descriptor: 26mer-DNA
Authors:Liu, Y, Li, J, Zhang, Y, Wang, Y, Chen, J, Bian, Y, Xia, Y, Yang, M.H, Zheng, K, Wang, K.B, Kong, L.Y.
Deposit date:2023-05-18
Release date:2023-08-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-Back Loop.
J.Am.Chem.Soc., 145, 2023
5FBJ
DownloadVisualize
BU of 5fbj by Molmil
Complex structure of JMJD5 and substrate
Descriptor: (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, 2-OXOGLUTARIC ACID, Lysine-specific demethylase 8, ...
Authors:Liu, H.L, Wang, Y, Wang, C, Zhang, G.Y.
Deposit date:2015-12-14
Release date:2016-12-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:to be published
To Be Published
1X6N
DownloadVisualize
BU of 1x6n by Molmil
Crystal structure of S. marcescens chitinase A mutant W167A in complex with allosamidin
Descriptor: 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, Chitinase A
Authors:Aronson Jr, N.N, Halloran, B.A, Alexyev, M.F, Zhou, X.E, Wang, Y, Meehan, E.J, Chen, L.
Deposit date:2004-08-11
Release date:2005-07-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Muation of Trp167 at the -3 subsite of the chitin-binding cleft of S. marcescens chitinase A causes enhanced transglycosylation
To be Published
6D88
DownloadVisualize
BU of 6d88 by Molmil
Tubulin-RB3_SLD-TTL in complex with compound 13f
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Kumar, G, Wang, Y, Li, W, White, S.W.
Deposit date:2018-04-26
Release date:2018-09-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.853 Å)
Cite:Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities.
J. Med. Chem., 61, 2018
4R0T
DownloadVisualize
BU of 4r0t by Molmil
Crystal structure of P. aeruginosa TpbA (C132S) in complex with pTyr
Descriptor: PHOSPHATE ION, Protein tyrosine phosphatase TpbA, TYROSINE
Authors:Xu, K, Li, S, Wang, Y, Bartlam, M.
Deposit date:2014-08-01
Release date:2015-05-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1
Plos One, 10
1YU5
DownloadVisualize
BU of 1yu5 by Molmil
Crystal Structure of the Headpiece Domain of Chicken Villin
Descriptor: Villin
Authors:Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J.
Deposit date:2005-02-11
Release date:2005-09-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High-resolution crystal structures of villin headpiece and mutants with reduced f-actin binding activity.
Biochemistry, 44, 2005
1YU8
DownloadVisualize
BU of 1yu8 by Molmil
Crystal Structure of the R37A Mutant of Villin Headpiece
Descriptor: Villin
Authors:Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J.
Deposit date:2005-02-12
Release date:2005-09-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity.
Biochemistry, 44, 2005
6KFP
DownloadVisualize
BU of 6kfp by Molmil
Crystal structure of MavC ternary complex
Descriptor: MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N
Authors:Mu, Y, Wang, Y, Han, Y, Li, D, Feng, Y.
Deposit date:2019-07-08
Release date:2020-04-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
1YU7
DownloadVisualize
BU of 1yu7 by Molmil
Crystal Structure of the W64Y mutant of Villin Headpiece
Descriptor: Villin
Authors:Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J.
Deposit date:2005-02-12
Release date:2005-09-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity.
Biochemistry, 44, 2005

223166

数据于2024-07-31公开中

PDB statisticsPDBj update infoContact PDBjnumon