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PDB: 1092 件

5ZRZ
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Crystal Structure of EphA5/SAMD5 Complex
分子名称: Ephrin type-A receptor 5, Sterile alpha motif domain-containing protein 5
著者Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
登録日2018-04-25
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
1T8P
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Crystal structure of Human erythrocyte 2,3-bisphosphoglycerate mutase
分子名称: Bisphosphoglycerate mutase
著者Wang, Y, Wei, Z, Bian, Q, Cheng, Z, Wan, M, Liu, L, Gong, W.
登録日2004-05-13
公開日2004-08-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human bisphosphoglycerate mutase
J.Biol.Chem., 279, 2004
5ZRX
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Crystal Structure of EphA2/SHIP2 Complex
分子名称: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2
著者Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
登録日2018-04-25
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
5ZRY
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Crystal Structure of EphA6/Odin Complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, ...
著者Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
登録日2018-04-25
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
6O5B
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Monomer of a cation channel
分子名称: CALCIUM ION, Calcium uniporter protein, mitochondrial, ...
著者Wang, Y, Bai, X, Jiang, Y.
登録日2019-03-01
公開日2019-05-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter.
Cell, 177, 2019
6ON3
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A substrate bound structure of L-DOPA dioxygenase from Streptomyces sclerotialus
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,4-DIHYDROXYPHENYLALANINE, FE (II) ION, ...
著者Wang, Y, Shin, I, Fu, Y, Colabroy, K, Liu, A.
登録日2019-04-19
公開日2019-06-26
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal Structures of L-DOPA Dioxygenase fromStreptomyces sclerotialus.
Biochemistry, 58, 2019
4X3O
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Sirt2 in complex with a myristoyl peptide
分子名称: 1,2-ETHANEDIOL, NAD-dependent protein deacetylase sirtuin-2, ZINC ION, ...
著者Wang, Y, Zhang, W.Z, Hao, Q.
登録日2014-12-01
公開日2016-01-13
最終更新日2022-04-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Deacylation Mechanism by SIRT2 Revealed in the 1'-SH-2'-O-Myristoyl Intermediate Structure.
Cell Chem Biol, 24, 2017
4X3P
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Sirt2 in complex with a myristoyl peptide
分子名称: 1,2-ETHANEDIOL, CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NAD-dependent protein deacetylase sirtuin-2, ...
著者Wang, Y, Zhang, W, Hao, Q.
登録日2014-12-01
公開日2016-01-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Deacylation Mechanism by SIRT2 Revealed in the 1'-SH-2'-O-Myristoyl Intermediate Structure.
Cell Chem Biol, 24, 2017
4M8M
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Crystal structure of the active dimer of zebrafish PlexinC1 cytoplasmic region
分子名称: GCN4 coiled-coil fused zebrafish PlexinC1
著者Wang, Y, Pascoe, H.G, Zhang, X.
登録日2013-08-13
公開日2013-10-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.307 Å)
主引用文献Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin.
Elife, 2, 2013
5WQJ
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Crystal structure of 3-Mercaptopyruvate Sulfurtransferase(3MST) in complex with compound1
分子名称: 2-[2-[(4-oxidanylidene-3~{H}-quinazolin-2-yl)sulfanyl]ethanoylamino]thiophene-3-carboxamide, SODIUM ION, Sulfurtransferase
著者Suwanai, Y, Toma-Fukai, S, Shimizu, T.
登録日2016-11-27
公開日2017-09-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide
Sci Rep, 7, 2017
5WQK
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Crystal structure of 3-Mercaptopyruvate Sulfurtransferase(3MST) in complex with compound1
分子名称: 4-methyl-2-(2-naphthalen-1-yl-2-oxidanylidene-ethyl)sulfanyl-1~{H}-pyrimidin-6-one, SODIUM ION, Sulfurtransferase
著者Suwanai, Y, Toma-Fukai, S, Shimizu, T.
登録日2016-11-27
公開日2017-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide
Sci Rep, 7, 2017
2QFL
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Structure of SuhB: Inositol monophosphatase and extragenic suppressor from E. coli
分子名称: ACETATE ION, ETHYL ACETATE, Inositol-1-monophosphatase
著者Wang, Y, Stieglitz, K.A, Bubunenko, M, Court, D, Stec, B, Roberts, M.F.
登録日2007-06-27
公開日2007-07-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of the R184A mutant of the inositol monophosphatase encoded by suhB and implications for its functional interactions in Escherichia coli.
J.Biol.Chem., 282, 2007
6KG6
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Crystal structure of MavC/UBE2N-Ub complex
分子名称: MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N
著者Wang, Y, Huang, Y, Chang, M, Feng, Y.
登録日2019-07-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
6DFQ
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mouse diabetogenic TCR I.29
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, TCR alpha chain, ...
著者Wang, Y, Dai, S.
登録日2018-05-15
公開日2019-04-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFV
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Mouse diabetogenic TCR 8F10
分子名称: 1,2-ETHANEDIOL, TCR alpha chain, TCR beta chain
著者Wang, Y, Dai, S.
登録日2018-05-15
公開日2019-04-17
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFW
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TCR 8F10 in complex with IAg7-p8G9E
分子名称: 8F10 alpha chain, 8F10 beta chain, H-2 class II histocompatibility antigen, ...
著者Wang, Y, Dai, S.
登録日2018-05-15
公開日2019-04-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFS
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mouse TCR I.29 in complex with IAg7-p8E9E6ss
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class II histocompatibility antigen, A-D alpha chain, ...
著者Wang, Y, Dai, S.
登録日2018-05-15
公開日2019-04-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
2FSZ
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BU of 2fsz by Molmil
A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta
分子名称: 4-HYDROXYTAMOXIFEN, Estrogen receptor beta
著者Wang, Y.
登録日2006-01-23
公開日2006-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta
Proc.Natl.Acad.Sci.Usa, 103, 2006
6KZD
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Crystal structure of TRKc in complex with 3-((6-(4-aminophenyl)imidazo[1,2-a]pyrazin-3-yl)ethynyl)- N-(3-isopropyl-5-((4-methylpiperazin-1-yl)methyl)phenyl)-2- methylbenzamide
分子名称: 3-[2-[6-(4-aminophenyl)imidazo[1,2-a]pyrazin-3-yl]ethynyl]-2-methyl-~{N}-[3-(4-methylpiperazin-1-yl)-5-propan-2-yl-phenyl]benzamide, NT-3 growth factor receptor, PHOSPHATE ION
著者Wang, Y, Zhang, Z.M.
登録日2019-09-23
公開日2019-10-09
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.708 Å)
主引用文献Design, synthesis and biological evaluation of 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methylbenzamides as potent and selective pan-tropomyosin receptor kinase (TRK) inhibitors.
Eur.J.Med.Chem., 179, 2019
3KCU
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Structure of formate channel
分子名称: 2-(6-(2-CYCLOHEXYLETHOXY)-TETRAHYDRO-4,5-DIHYDROXY-2(HYDROXYMETHYL)-2H-PYRAN-3-YLOXY)-TETRAHYDRO-6(HYDROXYMETHYL)-2H-PY RAN-3,4,5-TRIOL, Probable formate transporter 1
著者Wang, Y, Huang, Y, Wang, J, Yan, N, Shi, Y.
登録日2009-10-22
公開日2009-12-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.243 Å)
主引用文献Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
3KCV
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Structure of formate channel
分子名称: Probable formate transporter 1
著者Wang, Y, Huang, Y, Wang, J, Yan, N, Shi, Y.
登録日2009-10-22
公開日2009-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.198 Å)
主引用文献Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
6LK0
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Crystal structure of human wild type TRIP13
分子名称: Pachytene checkpoint protein 2 homolog
著者Wang, Y, Huang, J, Li, B, Xue, H, Tricot, G, Hu, L, Xu, Z, Sun, X, Chang, S, Gao, L, Tao, Y, Xu, H, Xie, Y, Xiao, W, Yu, D, Kong, Y, Chen, G, Sun, X, Lian, F, Zhang, N, Wu, X, Mao, Z, Zhan, F, Zhu, W, Shi, J.
登録日2019-12-17
公開日2020-01-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Cancer Res., 80, 2020
8UEJ
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ssRNA phage PhiCb5 virion
分子名称: CALCIUM ION, Coat protein, Maturation protein
著者Wang, Y, Zhang, J.
登録日2023-10-01
公開日2024-05-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural mechanisms of Tad pilus assembly and its interaction with an RNA virus.
Sci Adv, 10, 2024
8UCR
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PhiCb5 maturation protein with Caulobacter crescentus bNY30a pili
分子名称: Flp family type IVb pilin, Maturation protein
著者Wang, Y, Zhang, J.
登録日2023-09-27
公開日2024-05-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (6.45 Å)
主引用文献Structural mechanisms of Tad pilus assembly and its interaction with an RNA virus.
Sci Adv, 10, 2024
6XJV
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MCU holocomplex in High-calcium state
分子名称: Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ...
著者Wang, Y, Jiang, Y.
登録日2020-06-24
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.17 Å)
主引用文献Structural insights into the Ca 2+ -dependent gating of the human mitochondrial calcium uniporter.
Elife, 9, 2020

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