3TKR
| Crystal structure of full-length human peroxiredoxin 4 with T118E mutation | 分子名称: | Peroxiredoxin-4 | 著者 | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | 登録日 | 2011-08-28 | 公開日 | 2011-10-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
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6PAF
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6LSA
| Complex structure of bovine herpesvirus 1 glycoprotein D and bovine nectin-1 IgV | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ... | 著者 | Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W. | 登録日 | 2020-01-17 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | 主引用文献 | Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor. Sci Adv, 6, 2020
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6LS9
| Crystal structure of bovine herpesvirus 1 glycoprotein D | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D | 著者 | Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W. | 登録日 | 2020-01-17 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor. Sci Adv, 6, 2020
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1HKL
| FREE AND LIGANDED FORM OF AN ESTEROLYTIC CATALYTIC ANTIBODY | 分子名称: | 48G7 FAB | 著者 | Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C. | 登録日 | 1996-12-20 | 公開日 | 1997-03-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Crystal structures of the free and liganded form of an esterolytic catalytic antibody. J.Mol.Biol., 268, 1997
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4LV9
| Fragment-based Identification of Amides Derived From trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | 分子名称: | 1,2-ETHANEDIOL, 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, Nicotinamide phosphoribosyltransferase, ... | 著者 | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | 登録日 | 2013-07-26 | 公開日 | 2013-09-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.807 Å) | 主引用文献 | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 23, 2013
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4LVF
| Fragment-based Identification of Amides Derived From trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | 分子名称: | (1S,2S)-2-phenyl-N-(pyridin-4-yl)cyclopropanecarboxamide, 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, ... | 著者 | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | 登録日 | 2013-07-26 | 公開日 | 2013-09-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 23, 2013
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1LVR
| IC3 of CB1 (L431A,A432L) Bound to G(alpha)i | 分子名称: | Cannabinoid receptor 1 | 著者 | Ulfers, A.L, McMurry, J.L, Miller, A, Wang, L, Kendall, D.A, Mierke, D.F. | 登録日 | 2002-05-29 | 公開日 | 2002-12-11 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity. Protein Sci., 11, 2002
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3TKS
| Crystal structure of full-length human peroxiredoxin 4 in three different redox states | 分子名称: | PEROXIDE ION, Peroxiredoxin-4 | 著者 | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | 登録日 | 2011-08-28 | 公開日 | 2011-10-05 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
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1J4I
| crystal structure analysis of the FKBP12 complexed with 000308 small molecule | 分子名称: | 4-METHYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PENTANOIC ACID, FKBP12 | 著者 | Li, P, Ding, Y, Wang, L, Wu, B, Shu, C, Li, S, Shen, B, Rao, Z. | 登録日 | 2001-09-30 | 公開日 | 2003-06-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Design and structure-based study of new potential FKBP12 inhibitors. Biophys.J., 85, 2003
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8WJL
| Cryo-EM structure of 6-subunit Smc5/6 hinge region | 分子名称: | E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, Structural maintenance of chromosomes protein 6 | 著者 | Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L. | 登録日 | 2023-09-26 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (6.15 Å) | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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1SPB
| SUBTILISIN BPN' PROSEGMENT (77 RESIDUES) COMPLEXED WITH A MUTANT SUBTILISIN BPN' (266 RESIDUES). CRYSTAL PH 4.6. CRYSTALLIZATION TEMPERATURE 20 C DIFFRACTION TEMPERATURE-160 C | 分子名称: | SODIUM ION, SUBTILISIN BPN', SUBTILISIN BPN' PROSEGMENT | 著者 | Gallagher, D.T, Gilliland, G.L, Wang, L, Bryan, P.N. | 登録日 | 1995-06-21 | 公開日 | 1995-10-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'. Structure, 3, 1995
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8WJN
| Cryo-EM structure of 6-subunit Smc5/6 head region | 分子名称: | Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosomes element 1, Non-structural maintenance of chromosomes element 4, ... | 著者 | Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L. | 登録日 | 2023-09-26 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (5.58 Å) | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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8WJO
| Cryo-EM structure of 8-subunit Smc5/6 arm region | 分子名称: | DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, ... | 著者 | Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L. | 登録日 | 2023-09-26 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (6.04 Å) | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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3R7W
| Crystal Structure of Gtr1p-Gtr2p complex | 分子名称: | GTP-binding protein GTR1, GTP-binding protein GTR2, MAGNESIUM ION, ... | 著者 | Gong, R, Li, L, Liu, Y, Wang, P, Yang, H, Wang, L, Cheng, J, Guan, K.L, Xu, Y. | 登録日 | 2011-03-23 | 公開日 | 2011-08-24 | 最終更新日 | 2013-06-19 | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | 主引用文献 | Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation Genes Dev., 25, 2011
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1L3M
| The Solution Structure of [d(CGC)r(amamam)d(TTTGCG)]2 | 分子名称: | 5'-D(*CP*GP*C)-R(P*(A39)P*(A39)P*(A39))-D(P*TP*TP*TP*GP*CP*G)-3' | 著者 | Tsao, Y.P, Wang, L.Y, Hsu, S.T, Jain, M.L, Chou, S.H, Huang, W.C, Cheng, J.W. | 登録日 | 2002-02-28 | 公開日 | 2002-04-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of [d(CGC)r(amamam)d(TTTGCG)]2. J.Biomol.NMR, 21, 2001
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5G0I
| Crystal structure of Danio rerio HDAC6 CD1 and CD2 (linker cleaved) in complex with Nexturastat A | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, HDAC6, ... | 著者 | Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P. | 登録日 | 2016-03-18 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition Nat.Chem.Biol., 12, 2016
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3FXO
| Crystal Structure of Human Protein phosphatase 1A (PPM1A) Bound with Phosphate at 1 mM of Mn2+ | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, Protein phosphatase 1A | 著者 | Hu, T, Wang, L, Wang, K, Jiang, H, Shen, X. | 登録日 | 2009-01-21 | 公開日 | 2010-01-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the Mn2+-dependent activation of human PPM1A To be published
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6OMM
| Cryo-EM structure of formyl peptide receptor 2/lipoxin A4 receptor in complex with Gi | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhuang, Y, Liu, H, de Waal, P.W, Zhou, X.E, Wang, L, Meng, X, Zhao, G, Kang, Y, Melcher, K, Xu, H.E, Zhang, C. | 登録日 | 2019-04-19 | 公開日 | 2020-02-26 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Structure of formylpeptide receptor 2-Gicomplex reveals insights into ligand recognition and signaling. Nat Commun, 11, 2020
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3FXM
| Crystal Structure of Human Protein phosphatase 1A (PPM1A) Bound with Citrate at 10 mM of Mn2+ | 分子名称: | CITRATE ANION, MANGANESE (II) ION, PHOSPHATE ION, ... | 著者 | Hu, T, Wang, L, Wang, K, Jiang, H, Shen, X. | 登録日 | 2009-01-21 | 公開日 | 2010-01-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the Mn2+-dependent activation of human PPM1A To be published
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5G0H
| Crystal structure of Danio rerio HDAC6 CD2 in complex with (S)- trichostatin A | 分子名称: | 1,2-ETHANEDIOL, HDAC6, POTASSIUM ION, ... | 著者 | Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P. | 登録日 | 2016-03-18 | 公開日 | 2016-07-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition Nat.Chem.Biol., 12, 2016
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3FXJ
| Crystal Structure of Human Protein phosphatase 1A (PPM1A) Bound with Phosphate at 3 mM of Mn2+ | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, Protein phosphatase 1A | 著者 | Hu, T, Wang, L, Wang, K, Jiang, H, Shen, X. | 登録日 | 2009-01-21 | 公開日 | 2010-01-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the Mn2+-dependent activation of human PPM1A To be published
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3FXK
| Crystal Structure of Human Protein phosphatase 1A (PPM1A) Bound with Phosphate at 10 mM of Mn2+ | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, Protein phosphatase 1A | 著者 | Hu, T, Wang, L, Wang, K, Jiang, H, Shen, X. | 登録日 | 2009-01-21 | 公開日 | 2010-01-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for the Mn2+-dependent activation of human PPM1A To be published
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3J1B
| Cryo-EM structure of 8-fold symmetric rATcpn-alpha in apo state | 分子名称: | Chaperonin alpha subunit | 著者 | Zhang, K, Wang, L, Liu, Y.X, Wang, X, Gao, B, Hu, Z.J, Ji, G, Chan, K.Y, Schulten, K, Dong, Z.Y, Sun, F. | 登録日 | 2012-02-06 | 公開日 | 2013-08-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Flexible interwoven termini determine the thermal stability of thermosomes. Protein Cell, 4, 2013
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3J1E
| Cryo-EM structure of 9-fold symmetric rATcpn-beta in apo state | 分子名称: | Chaperonin beta subunit | 著者 | Zhang, K, Wang, L, Liu, Y.X, Wang, X, Gao, B, Hu, Z.J, Ji, G, Chan, K.Y, Schulten, K, Dong, Z.Y, Sun, F. | 登録日 | 2012-02-06 | 公開日 | 2013-08-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | 主引用文献 | Flexible interwoven termini determine the thermal stability of thermosomes. Protein Cell, 4, 2013
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