4O4E
 
 | | Crystal Structure of an Inositol hexakisphosphate kinase EhIP6KA in complexed with ATP and Ins(1,3,4,5,6)P5 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Inositol hexakisphosphate kinase, MAGNESIUM ION, ... | | 著者 | Wang, H, Shears, S.B. | | 登録日 | 2013-12-18 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | IP6K structure and the molecular determinants of catalytic specificity in an inositol phosphate kinase family.
Nat Commun, 5, 2014
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7BFF
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7BFE
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8TYV
 | | Crystal structure of the SPX domain of XPR1 in complex with IP8 | | 分子名称: | (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], Solute carrier family 53 member 1 | | 著者 | Wang, H, Shears, S.B. | | 登録日 | 2023-08-25 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Co-ordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate, IP8
To Be Published
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8TYU
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3A6N
 | | The nucleosome containing a testis-specific histone variant, human H3T | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Tachiwana, H, Kagawa, W, Osakabe, A, Koichiro, K, Shiga, T, Kimura, H, Kurumizaka, H. | | 登録日 | 2009-09-04 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T
Proc.Natl.Acad.Sci.USA, 107, 2010
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4O4B
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4O4C
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3AV1
 | | The human nucleosome structure containing the histone variant H3.2 | | 分子名称: | 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Tachiwana, H, Osakabe, A, Shiga, T, Miya, Y, Kimura, H, Kagawa, W, Kurumizaka, H. | | 登録日 | 2011-02-18 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of human nucleosomes containing major histone H3 variants
Acta Crystallogr.,Sect.D, 67, 2011
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3AV2
 | | The human nucleosome structure containing the histone variant H3.3 | | 分子名称: | 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Tachiwana, H, Osakabe, A, Shiga, T, Miya, M, Kimura, H, Kagawa, W, Kurumizaka, H. | | 登録日 | 2011-02-18 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of human nucleosomes containing major histone H3 variants
Acta Crystallogr.,Sect.D, 67, 2011
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3AFA
 | | The human nucleosome structure | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Tachiwana, H, Kagawa, W, Osakabe, A, Koichiro, K, Shiga, T, Kimura, H, Kurumizaka, H. | | 登録日 | 2010-02-24 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T
Proc.Natl.Acad.Sci.USA, 107, 2010
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3AN2
 | | The structure of the centromeric nucleosome containing CENP-A | | 分子名称: | 147 mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Tachiwana, H, Kagawa, W, Shiga, T, Saito, K, Osakabe, A, Hayashi-Takanaka, Y, Park, S.-Y, Kimura, H, Kurumizaka, H. | | 登録日 | 2010-08-27 | | 公開日 | 2011-07-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Crystal structure of the human centromeric nucleosome containing CENP-A
Nature, 476, 2011
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6KZ4
 | | YebT domain 5-7 | | 分子名称: | Intermembrane transport protein YebT | | 著者 | Wang, H.W, Liu, C, Zhang, L. | | 登録日 | 2019-09-23 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM Structure of a Bacterial Lipid Transporter YebT.
J.Mol.Biol., 432, 2020
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6KZ3
 | | YebT domain1-4 | | 分子名称: | Intermembrane transport protein YebT | | 著者 | Wang, H.W, Liu, C, Zhang, L. | | 登録日 | 2019-09-23 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM Structure of a Bacterial Lipid Transporter YebT.
J.Mol.Biol., 432, 2020
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3T9B
 | | Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP at pH 5.2 | | 分子名称: | Inositol Pyrophosphate Kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | | 登録日 | 2011-08-02 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding.
Nat.Chem.Biol., 8, 2011
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6LIV
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6LK5
 | | MLKL mutant - T357ES358D | | 分子名称: | Mixed lineage kinase domain-like protein | | 著者 | Wang, H.Y, Li, S, Zhang, Y. | | 登録日 | 2019-12-18 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The MLKL kinase-like domain dimerization is an indispensable step of mammalian MLKL activation in necroptosis signaling.
Cell Death Dis, 12, 2021
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3USM
 | | Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles (collected at 1.2 A) | | 分子名称: | IODIDE ION, PHOSPHOCHOLINE, SELENOMETHIONINE, ... | | 著者 | Wang, H, Elferich, J, Gouaux, E. | | 登録日 | 2011-11-23 | | 公開日 | 2012-01-11 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.008 Å) | | 主引用文献 | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
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3T99
 | | Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and in the absence of cadmium at pH 7.0 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Inositol Pyrophosphate Kinase, MAGNESIUM ION | | 著者 | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | | 登録日 | 2011-08-02 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding.
Nat.Chem.Biol., 8, 2011
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6N5C
 | | Crystal structure of the catalytic domain of PPIP5K2 in complex with AMPPNP and 5-PCF2Am-InsP5 | | 分子名称: | (1,1-difluoro-2-oxo-2-{[(1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]amino}ethyl)phosphonic acid, 1,2-ETHANEDIOL, ACETATE ION, ... | | 著者 | Wang, H, Shears, S.B, Riley, A, Potter, B. | | 登録日 | 2018-11-21 | | 公開日 | 2019-08-21 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Synthesis of an alpha-phosphono-alpha , alpha-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7.
Medchemcomm, 10, 2019
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7YG3
 | | Crystal structure of HLA-B*13:01 | | 分子名称: | ARG-GLN-ASP-ILE-LEU-ASP-LEU-TRP-ILE, Beta-2-microglobulin, MHC class I antigen | | 著者 | Wang, H.S, Ouyang, S.Y. | | 登録日 | 2022-07-11 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity.
J.Biomed.Sci., 29, 2022
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5THR
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7DE7
 | | Crystal structure of PDZD7 HHD domain | | 分子名称: | (2R)-2-{[(2R)-2-{[(2S)-2-{[(2R)-2-hydroxypropyl]oxy}propyl]oxy}propyl]oxy}propan-1-ol, PDZ domain-containing protein 7 | | 著者 | Wang, H, Lin, L, Lu, Q. | | 登録日 | 2020-11-02 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Structure and Membrane Targeting of the PDZD7 Harmonin Homology Domain (HHD) Associated With Hearing Loss.
Front Cell Dev Biol, 9, 2021
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7XYD
 | | Crystal structure of TMPRSS2 in complex with Nafamostat | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ... | | 著者 | Wang, H, Liu, X, Duan, Y, Liu, X, Sun, L, Yang, H. | | 登録日 | 2022-06-01 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
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7Y0F
 | | Crystal structure of TMPRSS2 in complex with UK-371804 | | 分子名称: | 2-[(1-carbamimidamido-4-chloranyl-isoquinolin-7-yl)sulfonylamino]-2-methyl-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H. | | 登録日 | 2022-06-04 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
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