8TYV

Crystal structure of the SPX domain of XPR1 in complex with IP8

Summary for 8TYV

Entry DOI	10.2210/pdb8tyv/pdb
Descriptor	Solute carrier family 53 member 1, (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)] (3 entities in total)
Functional Keywords	transferase, inositol diphosphoinositol pentakisphosphate kinase, analog methylenebisphosphonate, ppip5k atp-grasp, pyrophosphate diphosphate
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	42797.26
Authors	Wang, H.,Shears, S.B. (deposition date: 2023-08-25, release date: 2024-06-12)
Primary citation	Wang, H.,Shears, S. Co-ordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate, IP8 To Be Published,
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation