3T99
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and in the absence of cadmium at pH 7.0
Summary for 3T99
| Entry DOI | 10.2210/pdb3t99/pdb |
| Related | 3T54 3T7A 3T9A 3T9B 3T9C 3T9D 3T9E 3T9F |
| Descriptor | Inositol Pyrophosphate Kinase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
| Functional Keywords | atp-grasp fold, inositol pyrophosphate kinase, phosphoryl transferase, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm, cytosol: O43314 |
| Total number of polymer chains | 1 |
| Total formula weight | 38441.09 |
| Authors | Wang, H.,Falck, J.,Hall, T.M.T.,Shears, S.B. (deposition date: 2011-08-02, release date: 2011-12-07, Last modification date: 2024-02-28) |
| Primary citation | Wang, H.,Falck, J.R.,Hall, T.M.,Shears, S.B. Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8:111-116, 2011 Cited by PubMed: 22119861DOI: 10.1038/nchembio.733 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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