3T99
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and in the absence of cadmium at pH 7.0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inositol Pyrophosphate Kinase | polymer | 334 | 37965.3 | 1 | UniProt (O43314) Pfam (PF18086) | Homo sapiens (human) | |
| 2 | B (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E (A) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence modifications
A: 37 - 366 (UniProt: O43314)
| PDB | External Database | Details |
|---|---|---|
| Gly 33 | - | expression tag |
| Ser 34 | - | expression tag |
| Phe 35 | - | expression tag |
| Thr 36 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37965.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 475.8 | |
| All* | Total formula weight | 38441.1 |
