6LK5

MLKL mutant - T357ES358D

Summary for 6LK5

• Entry DOI: 10.2210/pdb6lk5/pdb
• Descriptor: Mixed lineage kinase domain-like protein (2 entities in total)
• Functional Keywords: protein phosphorylation, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 54621.08

Authors

Wang, H.Y.,Li, S.,Zhang, Y. (deposition date: 2019-12-18, release date: 2020-12-23, Last modification date: 2023-11-22)

• Primary citation: Zhang, Y.,Liu, J.,Yu, D.,Zhu, X.,Liu, X.,Liao, J.,Li, S.,Wang, H.; The MLKL kinase-like domain dimerization is an indispensable step of mammalian MLKL activation in necroptosis signaling.; Cell Death Dis, 12:638-638, 2021; PubMed: 34158471; DOI: 10.1038/s41419-021-03859-6

Experimental method

X-RAY DIFFRACTION (2.5 Å)