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6LK5

MLKL mutant - T357ES358D

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0004672molecular_functionprotein kinase activity
A0004674molecular_functionprotein serine/threonine kinase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006468biological_processprotein phosphorylation
A0007166biological_processcell surface receptor signaling pathway
A0012501biological_processprogrammed cell death
A0016020cellular_componentmembrane
A0019901molecular_functionprotein kinase binding
A0030054cellular_componentcell junction
A0044877molecular_functionprotein-containing complex binding
A0051607biological_processdefense response to virus
A0070207biological_processprotein homotrimerization
A0070266biological_processnecroptotic process
A0097527biological_processnecroptotic signaling pathway
A0097528biological_processexecution phase of necroptosis
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

239492

PDB entries from 2025-07-30

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