8JNZ
 
 | | Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a pyrazolopyrimidine carboxamide inhibitor | | 分子名称: | 6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide, Poly [ADP-ribose] polymerase 1, processed C-terminus, ... | | 著者 | Wang, X.Y, Wang, C.Y, Zhou, J, Xu, B.L. | | 登録日 | 2023-06-06 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a pyrazolopyrimidine carboxamide inhibitor
To Be Published
|
|
8E3H
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, Mg-ADP-BeF3, and NusG; Rho hexamer part | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Molodtsov, V, Wang, C. | | 登録日 | 2022-08-17 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
|
|
8E6Z
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, dC75 rut mimic RNA, Mg-ADP-BeF3, and NusG; TEC part | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | | 登録日 | 2022-08-23 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
|
|
8E5O
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 24 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Molodtsov, V, Wang, C. | | 登録日 | 2022-08-22 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
|
|
8E3F
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Molodtsov, V, Wang, C. | | 登録日 | 2022-08-17 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
|
|
8E5K
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 21 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Molodtsov, V, Wang, C. | | 登録日 | 2022-08-22 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
|
|
8E5P
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 24 nt long RNA spacer, Mg-ADP-BeF3, and NusG; Rho hexamer part | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Molodtsov, V, Wang, C. | | 登録日 | 2022-08-22 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
|
|
8E6W
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, lambda-tR1 rut RNA, Mg-ADP-BeF3, and NusG; Rho part | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | | 登録日 | 2022-08-23 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
|
|
8E6X
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, lambda-tR1 rut RNA, Mg-ADP-BeF3, and NusG; TEC part | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Molodtsov, V, Wang, C. | | 登録日 | 2022-08-23 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
|
|
8E70
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, dC75 rut mimic RNA, Mg-ADP-BeF3, and NusG; Rho hexamer part | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | | 登録日 | 2022-08-23 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
|
|
3LDB
 | | Structure of JMJD6 complexd with ALPHA-KETOGLUTARATE and Fab Fragment. | | 分子名称: | 2-OXOGLUTARIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, FE (III) ION, ... | | 著者 | Hong, X, Zang, J, White, J, Kappler, J.W, Wang, C, Zhang, G. | | 登録日 | 2010-01-12 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Interaction of JMJD6 with single-stranded RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
4LRV
 | | Crystal structure of DndE from Escherichia coli B7A involved in DNA phosphorothioation modification | | 分子名称: | DNA sulfur modification protein DndE | | 著者 | Hu, W, Wang, C.K, Liang, J.D, Zhang, T.L, Yang, M, Hu, Z.P, Wang, Z.J, Lan, W.X, Wu, H.M, Ding, J.P, Wu, G, Deng, Z.X, Cao, C. | | 登録日 | 2013-07-21 | | 公開日 | 2013-08-28 | | 最終更新日 | 2013-09-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insights into DndE from Escherichia coli B7A involved in DNA phosphorothioation modification
Cell Res., 22, 2012
|
|
1XMJ
 | | Crystal structure of human deltaF508 human NBD1 domain with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | | 著者 | Lewis, H.A, Zhao, X, Wang, C, Sauder, J.M, Rooney, I, Noland, B.W, Lorimer, D, Kearins, M.C, Conners, K, Condon, B, Maloney, P.C, Guggino, W.B, Hunt, J.F, Emtage, S, Structural GenomiX | | 登録日 | 2004-10-02 | | 公開日 | 2004-11-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure
J.Biol.Chem., 280, 2005
|
|
4LVA
 | | Fragment-based Identification of Amides Derived From trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | | 分子名称: | 1,2-ETHANEDIOL, N-(4-{[4-(pyrrolidin-1-yl)piperidin-1-yl]sulfonyl}benzyl)-2H-pyrido[4,3-e][1,2,4]thiadiazin-3-amine 1,1-dioxide, Nicotinamide phosphoribosyltransferase, ... | | 著者 | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | | 登録日 | 2013-07-26 | | 公開日 | 2013-09-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg.Med.Chem.Lett., 23, 2013
|
|
8WJY
 | | PKMYT1_Cocrystal_Cpd 4 | | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, ... | | 著者 | Wang, Y, Wang, C, Liu, T, Qi, H, Chen, S, Cai, X, Zhang, M, Aliper, A, Ren, F, Ding, X, Zhavoronkov, A. | | 登録日 | 2023-09-26 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer.
J.Med.Chem., 67, 2024
|
|
5EQJ
 | | Crystal structure of the two-subunit tRNA m1A58 methyltransferase from Saccharomyces cerevisiae | | 分子名称: | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 | | 著者 | Zhu, Y, Wang, M, Wang, C, Fan, X, Jiang, X, Teng, M, Li, X. | | 登録日 | 2015-11-13 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.
Sci Rep, 6, 2016
|
|
1FNT
 | | CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST IN COMPLEX WITH THE PROTEASOME ACTIVATOR PA26 FROM TRYPANOSOME BRUCEI AT 3.2 ANGSTROMS RESOLUTION | | 分子名称: | MAGNESIUM ION, PROTEASOME ACTIVATOR PROTEIN PA26, PROTEASOME COMPONENT C1, ... | | 著者 | Whitby, F.G, Masters, E, Kramer, L, Knowlton, J.R, Yao, Y, Wang, C.C, Hill, C.P. | | 登録日 | 2000-08-23 | | 公開日 | 2001-04-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for the activation of 20S proteasomes by 11S regulators.
Nature, 408, 2000
|
|
6DNF
 | |
7RIH
 | | hyen D | | 分子名称: | CITRATE ANION, Cyclotide hyen-D, D-[I11L]hyen D | | 著者 | Du, Q, Huang, Y.H, Craik, D.J, Wang, C.K. | | 登録日 | 2021-07-20 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Enabling efficient folding and high-resolution crystallographic analysis of bracelet cyclotides
Molecules, 26(18), 2021
|
|
5FBJ
 | | Complex structure of JMJD5 and substrate | | 分子名称: | (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, 2-OXOGLUTARIC ACID, Lysine-specific demethylase 8, ... | | 著者 | Liu, H.L, Wang, Y, Wang, C, Zhang, G.Y. | | 登録日 | 2015-12-14 | | 公開日 | 2016-12-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | to be published
To Be Published
|
|
8JY6
 | | Structure of TbAQP2 in complex with anti-trypanosomatid drug melarsoprol | | 分子名称: | Aquaglyceroporin 2, [(4~{R})-2-[4-[[4,6-bis(azanyl)-1,3,5-triazin-2-yl]amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol | | 著者 | Chen, W, Wang, C. | | 登録日 | 2023-07-03 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural insights into drug transport by an aquaglyceroporin.
Nat Commun, 15, 2024
|
|
8JY8
 | |
5WWZ
 | | Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C | | 分子名称: | RNA-binding E3 ubiquitin-protein ligase MEX3C, SULFATE ION | | 著者 | Yang, L, Wang, C, Li, F, Gong, Q. | | 登録日 | 2017-01-05 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
|
|
4MC2
 | | HIV protease in complex with SA525P | | 分子名称: | (3S)-tetrahydrofuran-3-yl {(2S,3R)-4-[(4R)-4-tert-butyl-7-fluoro-1,1-dioxido-4,5-dihydro-1,2-benzothiazepin-2(3H)-yl]-3-hydroxy-1-phenylbutan-2-yl}carbamate, CHLORIDE ION, Protease | | 著者 | Ganguly, A.K, Alluri, S.S, Wang, C, Caroccia, D, Biswas, D, Kang, E, Zhang, L, Carroll, S.S, Burlein, C, Munshi, V, Orth, P, Strickland, C. | | 登録日 | 2013-08-21 | | 公開日 | 2014-04-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Structural Optimization of Cyclic Sulfonamide based Novel HIV-1 Protease Inhibitors to Pico Molar Affinities guided by X-ray Crystallographic Analysis
Tetrahedron, 2014
|
|
4NC3
 | | Crystal structure of the 5-HT2B receptor solved using serial femtosecond crystallography in lipidic cubic phase. | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHOLESTEROL, ... | | 著者 | Liu, W, Wacker, D, Gati, C, Han, G.W, James, D, Wang, D, Nelson, G, Weierstall, U, Katritch, V, Barty, A, Zatsepin, N.A, Li, D, Messerschmidt, M, Boutet, S, Williams, G.J, Koglin, J.E, Seibert, M.M, Wang, C, Shah, S.T.A, Basu, S, Fromme, R, Kupitz, C, Rendek, K.N, Grotjohann, I, Fromme, P, Kirian, R.A, Beyerlein, K.R, White, T.A, Chapman, H.N, Caffrey, M, Spence, J.C.H, Stevens, R.C, Cherezov, V, GPCR Network (GPCR) | | 登録日 | 2013-10-23 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Serial femtosecond crystallography of G protein-coupled receptors.
Science, 342, 2013
|
|
