8JNZ

Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a pyrazolopyrimidine carboxamide inhibitor

Summary for 8JNZ

• Entry DOI: 10.2210/pdb8jnz/pdb
• Descriptor: Poly [ADP-ribose] polymerase 1, processed C-terminus, 6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide, SULFATE ION (3 entities in total)
• Functional Keywords: dna adp-ribosyltransferase 1, parp1, parp inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 79943.21

Authors

Wang, X.Y.,Wang, C.Y.,Zhou, J.,Xu, B.L. (deposition date: 2023-06-06, release date: 2024-06-12)

• Primary citation: Wang, X.Y.,Wang, C.Y.,Zhou, J.,Xu, B.L.; Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a pyrazolopyrimidine carboxamide inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.84 Å)