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PDB: 35 件

8FTQ
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Crystal structure of hRpn13 Pru domain in complex with Ubiquitin and XL44
分子名称: N-(3-{[(3R)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl]methyl}phenyl)-4-methoxybenzamide, Proteasomal ubiquitin receptor ADRM1, Ubiquitin
著者Walters, K.J, Lu, X, Chandravanshi, M.
登録日2023-01-13
公開日2024-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins.
Nat Commun, 15, 2024
1J8C
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Solution Structure of the Ubiquitin-like Domain of hPLIC-2
分子名称: ubiquitin-like protein hPLIC-2
著者Walters, K.J, Kleijnen, M.F, Goh, A.M, Wagner, G, Howley, P.M.
登録日2001-05-21
公開日2002-03-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a.
Biochemistry, 41, 2002
1CKV
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BU of 1ckv by Molmil
STRUCTURE OF THE SOLUBLE METHANE MONOOXYGENASE REGULATORY PROTEIN B
分子名称: PROTEIN (PROTEIN B)
著者Walters, K.J, Gassner, G.T, Lippard, S.J, Wagner, G.
登録日1999-04-25
公開日1999-07-07
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of the soluble methane monooxygenase regulatory protein B.
Proc.Natl.Acad.Sci.USA, 96, 1999
1AJY
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BU of 1ajy by Molmil
STRUCTURE AND MOBILITY OF THE PUT3 DIMER: A DNA PINCER, NMR, 13 STRUCTURES
分子名称: PUT3, ZINC ION
著者Walters, K.J, Dayie, K.T, Reece, R.J, Ptashne, M, Wagner, G.
登録日1997-05-12
公開日1997-09-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and mobility of the PUT3 dimer.
Nat.Struct.Biol., 4, 1997
1QZE
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BU of 1qze by Molmil
HHR23a protein structure based on residual dipolar coupling data
分子名称: UV excision repair protein RAD23 homolog A
著者Walters, K.J, Lech, P.J, Goh, A.M, Wang, Q, Howley, P.M.
登録日2003-09-16
公開日2003-10-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a
Proc.Natl.Acad.Sci.USA, 100, 2003
1OQY
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BU of 1oqy by Molmil
Structure of the DNA repair protein hHR23a
分子名称: UV excision repair protein RAD23 homolog A
著者Walters, K.J, Lech, P.J, Goh, A.M, Wang, Q, Howley, P.M.
登録日2003-03-11
公開日2003-10-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a
Proc.Natl.Acad.Sci.USA, 100, 2003
6CO4
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BU of 6co4 by Molmil
Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets
分子名称: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1
著者Lu, X, Walters, K.J.
登録日2018-03-11
公開日2018-04-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.
Nat Commun, 8, 2017
6E5N
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Solution structure of human Myosin VI isoform 3 (1050-1131) in complex with Clathrin light chain a (46-61)
分子名称: Clathrin light chain A, Unconventional myosin-VI
著者Buel, G.R, Walters, K.J.
登録日2018-07-20
公開日2019-11-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension.
Nat Commun, 10, 2019
8GI6
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BU of 8gi6 by Molmil
Crystal structure of RhoA mutant L69R complexed with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA
著者Chen, X, Qian, X, Chandravanshi, M, Lowy, D.R, Walters, K.J.
登録日2023-03-13
公開日2024-03-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Ras-like GTPases mutant structures
To be published
8GI3
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Crystal structure of RhoA mutant L69P complexed with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA
著者Chen, X, Qian, X, Chandravanshi, M, Lowy, D.R, Walters, K.J.
登録日2023-03-13
公開日2024-03-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Ras-like GTPases mutants structure
To be published
5W77
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Solution structure of the MYC G-quadruplex bound to small molecule DC-34
分子名称: 4-[(azepan-1-yl)methyl]-5-hydroxy-2-methyl-N-[4-(trifluoromethyl)phenyl]-1-benzofuran-3-carboxamide, DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), POTASSIUM ION
著者Chen, X, Walters, K.J.
登録日2017-06-19
公開日2018-10-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.
Nat Commun, 9, 2018
2I0N
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Structure of Dictyostelium discoideum Myosin VII SH3 domain with adjacent proline rich region
分子名称: Class VII unconventional myosin
著者Wang, Q, Deloia, M.A, Kang, Y, Litchke, C, Titus, M.A, Walters, K.J.
登録日2006-08-10
公開日2007-01-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The SH3 domain of a M7 interacts with its C-terminal proline-rich region.
Protein Sci., 16, 2007
6WJN
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BU of 6wjn by Molmil
SD-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Chen, X, Walters, K.J.
登録日2020-04-14
公開日2020-08-05
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
6WJD
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BU of 6wjd by Molmil
SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Chen, X, Walters, K.J.
登録日2020-04-13
公開日2020-08-05
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
6MUN
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BU of 6mun by Molmil
Structure of hRpn10 bound to UBQLN2 UBL
分子名称: 26S proteasome non-ATPase regulatory subunit 4, Ubiquilin-2
著者Chen, X, Walters, K.J.
登録日2018-10-23
公開日2019-09-04
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of hRpn10 Bound to UBQLN2 UBL Illustrates Basis for Complementarity between Shuttle Factors and Substrates at the Proteasome.
J.Mol.Biol., 431, 2019
6UYJ
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BU of 6uyj by Molmil
hRpn13:hRpn2:K48-diubiquitin
分子名称: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin
著者Lu, X, Walters, K.J.
登録日2019-11-13
公開日2020-03-11
最終更新日2020-05-20
実験手法SOLUTION NMR
主引用文献An Extended Conformation for K48 Ubiquitin Chains Revealed by the hRpn2:Rpn13:K48-Diubiquitin Structure.
Structure, 28, 2020
6UYI
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hRpn13:hRpn2:K48-diubiquitin
分子名称: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin
著者Lu, X, Walters, K.J.
登録日2019-11-13
公開日2020-03-11
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献An Extended Conformation for K48 Ubiquitin Chains Revealed by the hRpn2:Rpn13:K48-Diubiquitin Structure.
Structure, 28, 2020
6U19
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BU of 6u19 by Molmil
Solution Structure of the RAZUL domain from 26S proteasome subunit hRpn10/S5a complexed with the AZUL domain from E3 ligase E6AP/UBE3A
分子名称: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin-protein ligase E3A, ZINC ION
著者Chen, X, Walters, K.J.
登録日2019-08-15
公開日2020-03-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10.
Nat Commun, 11, 2020
2Z59
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BU of 2z59 by Molmil
Complex Structures of Mouse Rpn13 (22-130aa) and ubiquitin
分子名称: Protein ADRM1, Ubiquitin
著者Chen, X, Schreiner, P, Groll, M, Walters, K.J.
登録日2007-07-01
公開日2008-05-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction.
Nature, 453, 2008
2Z4D
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BU of 2z4d by Molmil
NMR Structures of Yeast Proteasome Component Rpn13
分子名称: 26S proteasome regulatory subunit RPN13
著者Zhang, N, Walters, K.J.
登録日2007-06-15
公開日2008-05-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Proteasome subunit Rpn13 is a novel ubiquitin receptor.
Nature, 453, 2008
2N3T
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BU of 2n3t by Molmil
Solution structure of the Rpn1 substrate receptor site toroid 1 (T1)
分子名称: 26S proteasome regulatory subunit RPN1
著者Chen, X, Walters, K.J.
登録日2015-06-10
公開日2016-02-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome.
Science, 351, 2016
2N3W
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BU of 2n3w by Molmil
Solution structure of the Rpn1 T1 site with K48-linked diubiquitin in the contracted binding mode
分子名称: 26S proteasome regulatory subunit RPN1, Ubiquitin-60S ribosomal protein L40
著者Chen, X, Walters, K.J.
登録日2015-06-10
公開日2016-02-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome.
Science, 351, 2016
1YX4
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Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition
分子名称: 26S proteasome non-ATPase regulatory subunit 4
著者Wang, Q, Young, P, Walters, K.J.
登録日2005-02-19
公開日2005-04-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition
J.Mol.Biol., 348, 2005
2N3V
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Solution structure of the Rpn1 T1 site with K48-linked diubiquitin in the extended binding mode
分子名称: 26S proteasome regulatory subunit RPN1, Ubiquitin-60S ribosomal protein L40
著者Chen, X, Walters, K.J.
登録日2015-06-10
公開日2016-02-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome.
Science, 351, 2016
2KQZ
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Solution structure of the Rpn13 DEUBAD domain
分子名称: Proteasomal ubiquitin receptor ADRM1
著者Chen, X, Lee, B, Finley, D, Walters, K.J.
登録日2009-11-25
公開日2010-05-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2.
Mol.Cell, 38, 2010

 

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