7PX3
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![BU of 7px3 by Molmil](/molmil-images/mine/7px3) | Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8 | Descriptor: | Pre-mRNA-processing-splicing factor 8, Protein TSSC4, U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Bergfort, A, Kuropka, B, Ilik, I.A, Freund, C, Aktas, T, Hilal, T, Weber, G, Wahl, M.C. | Deposit date: | 2021-10-07 | Release date: | 2022-01-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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3ELS
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![BU of 3els by Molmil](/molmil-images/mine/3els) | Crystal Structure of Yeast Pml1p, Residues 51-204 | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Trowitzsch, S, Weber, G, Luehrmann, R, Wahl, M.C. | Deposit date: | 2008-09-23 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. J.Mol.Biol., 385, 2009
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4R3F
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![BU of 4r3f by Molmil](/molmil-images/mine/4r3f) | Structure of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27 from Chaetomium thermophilum | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ACETATE ION, ... | Authors: | Ulrich, A, Wahl, M.C. | Deposit date: | 2014-08-15 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure and evolution of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27. Acta Crystallogr.,Sect.D, 70, 2014
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3ELV
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![BU of 3elv by Molmil](/molmil-images/mine/3elv) | Crystal Structure of Full-Length Yeast Pml1p | Descriptor: | Pre-mRNA leakage protein 1, SULFATE ION | Authors: | Trowitzsch, S, Weber, G, L hrmann, R, Wahl, M.C. | Deposit date: | 2008-09-23 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. J.Mol.Biol., 385, 2009
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3EGN
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![BU of 3egn by Molmil](/molmil-images/mine/3egn) | |
4RKF
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![BU of 4rkf by Molmil](/molmil-images/mine/4rkf) | Drosophila melanogaster Rab3 bound to GMPPNP | Descriptor: | MAGNESIUM ION, PENTAETHYLENE GLYCOL, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Lardong, J.A, Driller, J.H, Depner, H, Weise, C, Petzoldt, A, Wahl, M.C, Sigrist, S.J, Loll, B. | Deposit date: | 2014-10-13 | Release date: | 2014-12-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of Drosophila melanogaster Rab2 and Rab3 bound to GMPPNP. Acta Crystallogr F Struct Biol Commun, 71, 2015
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4ILJ
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![BU of 4ilj by Molmil](/molmil-images/mine/4ilj) | |
4ILI
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![BU of 4ili by Molmil](/molmil-images/mine/4ili) | |
4ILG
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![BU of 4ilg by Molmil](/molmil-images/mine/4ilg) | Crystal structure of Aar2p in complex with the Prp8p RNaseH and Jab1/MPN domains | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 | Authors: | Weber, G, Heroven, A.C, Santos, K.F, Wahl, M.C. | Deposit date: | 2012-12-31 | Release date: | 2013-03-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for dual roles of Aar2p in U5 snRNP assembly. Genes Dev., 27, 2013
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4ILH
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5JDT
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![BU of 5jdt by Molmil](/molmil-images/mine/5jdt) | Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at 100K | Descriptor: | AZIDE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Loll, B, Consentius, P, Gohlke, U, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. | Deposit date: | 2016-04-17 | Release date: | 2016-09-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Tracking Transient Conformational States of T4 Lysozyme at Room Temperature Combining X-ray Crystallography and Site-Directed Spin Labeling. J.Am.Chem.Soc., 138, 2016
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7BDK
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![BU of 7bdk by Molmil](/molmil-images/mine/7bdk) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, ... | Authors: | Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. | Deposit date: | 2020-12-21 | Release date: | 2021-06-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J.Biol.Chem., 297, 2021
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7BDL
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![BU of 7bdl by Molmil](/molmil-images/mine/7bdl) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ADP | Descriptor: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | Authors: | Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. | Deposit date: | 2020-12-21 | Release date: | 2021-06-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J.Biol.Chem., 297, 2021
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7BDJ
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![BU of 7bdj by Molmil](/molmil-images/mine/7bdj) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ATPgammaS | Descriptor: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | Authors: | Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. | Deposit date: | 2020-12-21 | Release date: | 2021-06-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J.Biol.Chem., 297, 2021
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7BDI
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![BU of 7bdi by Molmil](/molmil-images/mine/7bdi) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and ATPgammaS | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pre-mRNA-processing-splicing factor 8, ... | Authors: | Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. | Deposit date: | 2020-12-21 | Release date: | 2021-06-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J.Biol.Chem., 297, 2021
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8PTP
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![BU of 8ptp by Molmil](/molmil-images/mine/8ptp) | Structure of Rho pentamer in complex with Rof | Descriptor: | Protein rof, Transcription termination factor Rho | Authors: | Said, N, Hilal, T, Wahl, M.C. | Deposit date: | 2023-07-14 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation. Nat Commun, 15, 2024
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8PTN
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8PTG
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![BU of 8ptg by Molmil](/molmil-images/mine/8ptg) | Structure of the transcription termination factor Rho bound to RNA at the PBS and SBS | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Said, N, Hilal, T, Wahl, M.C. | Deposit date: | 2023-07-14 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation. Nat Commun, 15, 2024
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8PTM
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![BU of 8ptm by Molmil](/molmil-images/mine/8ptm) | Structure of the transcription termination factor Rho in complex with Rof and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein rof, ... | Authors: | Said, N, Hilal, T, Wahl, M.C. | Deposit date: | 2023-07-14 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation. Nat Commun, 15, 2024
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8PTO
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![BU of 8pto by Molmil](/molmil-images/mine/8pto) | Structure of Rho pentamer in complex with Rof and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Protein rof, Transcription termination factor Rho | Authors: | Said, N, Hilal, T, Wahl, M.C. | Deposit date: | 2023-07-14 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation. Nat Commun, 15, 2024
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7OS2
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![BU of 7os2 by Molmil](/molmil-images/mine/7os2) | Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78 | Descriptor: | Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | Deposit date: | 2021-06-07 | Release date: | 2022-02-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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7OS1
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![BU of 7os1 by Molmil](/molmil-images/mine/7os1) | Cryo-EM structure of Brr2 in complex with Fbp21 | Descriptor: | U5 small nuclear ribonucleoprotein 200 kDa helicase, WW domain-binding protein 4 | Authors: | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | Deposit date: | 2021-06-07 | Release date: | 2022-02-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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6GOV
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![BU of 6gov by Molmil](/molmil-images/mine/6gov) | Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX | Descriptor: | 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... | Authors: | Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. | Deposit date: | 2018-06-04 | Release date: | 2019-02-13 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor. Mol.Cell, 74, 2019
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6H5T
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![BU of 6h5t by Molmil](/molmil-images/mine/6h5t) | Intersectin SH3A short isoform | Descriptor: | 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, ACETATE ION, CHLORIDE ION, ... | Authors: | Driller, J.H, Gerth, F, Freund, C, Wahl, M.C, Loll, B. | Deposit date: | 2018-07-25 | Release date: | 2019-02-27 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.689 Å) | Cite: | Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain. Structure, 27, 2019
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6IB7
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![BU of 6ib7 by Molmil](/molmil-images/mine/6ib7) | Structure of wild type SuhB | Descriptor: | GLYCEROL, Inositol-1-monophosphatase, MAGNESIUM ION | Authors: | Huang, Y.H, Loll, B, Wahl, M.C. | Deposit date: | 2018-11-29 | Release date: | 2019-04-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.245 Å) | Cite: | Structural basis for the function of SuhB as a transcription factor in ribosomal RNA synthesis. Nucleic Acids Res., 47, 2019
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