4ILG

Crystal structure of Aar2p in complex with the Prp8p RNaseH and Jab1/MPN domains

Summary for 4ILG

• Entry DOI: 10.2210/pdb4ilg/pdb
• Related: 4ILH 4ILI 4ILJ
• Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
• Functional Keywords: u5 snrnp assembly, aar2, prp8, splicing
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Cellular location: Cytoplasm: P32357; Nucleus: P33334 P33334
• Total number of polymer chains: 3
• Total formula weight: 100449.62

Authors

Weber, G.,Heroven, A.C.,Santos, K.F.,Wahl, M.C. (deposition date: 2012-12-31, release date: 2013-03-13, Last modification date: 2023-09-20)

• Primary citation: Weber, G.,Cristao, V.F.,Santos, K.F.,Jovin, S.M.,Heroven, A.C.,Holton, N.,Luhrmann, R.,Beggs, J.D.,Wahl, M.C.; Structural basis for dual roles of Aar2p in U5 snRNP assembly.; Genes Dev., 27:525-540, 2013; PubMed: 23442228; DOI: 10.1101/gad.213207.113

Experimental method

X-RAY DIFFRACTION (2.1 Å)