4ILG
Crystal structure of Aar2p in complex with the Prp8p RNaseH and Jab1/MPN domains
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | A1 cistron-splicing factor AAR2 | polymer | 342 | 40219.9 | 1 | UniProt (P32357) Pfam (PF20981) Pfam (PF05282) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
2 | B | Pre-mRNA-splicing factor 8 | polymer | 258 | 29501.1 | 1 | UniProt (P33334) Pfam (PF12134) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
3 | C | Pre-mRNA-splicing factor 8 | polymer | 270 | 30490.3 | 1 | UniProt (P33334) Pfam (PF08084) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
4 | C | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
5 | water | water | 18.0 | 689 | Chemie (HOH) |
Sequence modifications
A: 1 - 355 (UniProt: P32357)
B: 1836 - 2090 (UniProt: P33334)
C: 2147 - 2413 (UniProt: P33334)
PDB | External Database | Details |
---|---|---|
Ser 153 | Leu 153 | engineered mutation |
Ser 154 | Lys 154 | engineered mutation |
- | Leu 157 | deletion |
- | Gln 158 | deletion |
- | Lys 159 | deletion |
- | Ala 160 | deletion |
- | Gly 161 | deletion |
- | Lys 163 | deletion |
- | Met 164 | deletion |
- | Glu 165 | deletion |
- | Ala 166 | deletion |
- | Lys 167 | deletion |
- | Asn 168 | deletion |
- | Glu 169 | deletion |
- | Asp 170 | deletion |
PDB | External Database | Details |
---|---|---|
Gly 1833 | - | expression tag |
Ala 1834 | - | expression tag |
Met 1835 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 2144 | - | expression tag |
Ala 2145 | - | expression tag |
Met 2146 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 100211.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 238.3 | |
All* | Total formula weight | 100449.6 |