4ILG

Crystal structure of Aar2p in complex with the Prp8p RNaseH and Jab1/MPN domains

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000387	biological_process	spliceosomal snRNP assembly
A	0003674	molecular_function	molecular_function
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005682	cellular_component	U5 snRNP
A	0005737	cellular_component	cytoplasm
A	0006397	biological_process	mRNA processing
A	0008380	biological_process	RNA splicing
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0005681	cellular_component	spliceosomal complex
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0005681	cellular_component	spliceosomal complex
C	0008233	molecular_function	peptidase activity
C	0008237	molecular_function	metallopeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EPE C 2501

Chain	Residue
C	PRO2352
C	SER2353
C	GLY2354
C	ASN2373
C	HOH2637
C	HOH2716
C	HOH2738

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:21764848

Chain	Residue	Details
A	GLU266
A	PRO344

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0000269|PubMed:21764848

Chain	Residue	Details
A	ARG287

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:21764848

Chain	Residue	Details
A	GLU341

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