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PDB: 578 results

2F5H
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BU of 2f5h by Molmil
Solution structure of the alpha-domain of human Metallothionein-3
Descriptor: CADMIUM ION, Metallothionein-3
Authors:Wang, H, Zhang, Q, Cai, B, Li, H.Y, Sze, K.H, Huang, Z.X, Wu, H.M, Sun, H.Z.
Deposit date:2005-11-25
Release date:2006-05-30
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure and dynamics of human metallothionein-3 (MT-3)
Febs Lett., 580, 2006
5JQE
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BU of 5jqe by Molmil
Crystal structure of caspase8 tDED
Descriptor: Sugar ABC transporter substrate-binding protein,Caspase-8 chimera
Authors:Fu, T, Li, Y, Lu, A, Wu, H.
Deposit date:2016-05-04
Release date:2016-10-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.157 Å)
Cite:Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol. Cell, 64, 2016
8BD1
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BU of 8bd1 by Molmil
Crystal structure of the RhsPWHH-RhsPI toxin-immunity pair
Descriptor: SMI1/KNR4 family protein, Type IV secretion protein Rhs
Authors:Chao, W.C.H, Wu, H.W, Li, H.
Deposit date:2022-10-18
Release date:2022-11-30
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Crystal structure of the RhsPWHH-RhsPI toxin-immunity pair
To Be Published
5K22
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BU of 5k22 by Molmil
Crystal structure of the complex between human PRL-2 phosphatase in reduced state and Bateman domain of human CNNM3
Descriptor: Metal transporter CNNM3, Protein tyrosine phosphatase type IVA 2
Authors:Kozlov, G, Wu, H, Gehring, K.
Deposit date:2016-05-18
Release date:2016-10-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Phosphocysteine in the PRL-CNNM pathway mediates magnesium homeostasis.
EMBO Rep., 17, 2016
6DLO
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BU of 6dlo by Molmil
Crystal structure of LRRK2 WD40 domain dimer
Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Zhang, P, Ru, H, Wang, L, Wu, H.
Deposit date:2018-06-02
Release date:2019-01-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the WD40 domain dimer of LRRK2.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
7SEK
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BU of 7sek by Molmil
Solution structure of the zinc finger domain of murine MetAP1, complexed with ZNG N-terminal peptide
Descriptor: COBW domain-containing protein 1,Methionine aminopeptidase 1 fusion, ZINC ION
Authors:Edmonds, K.A, Jordan, M.R, Thalluri, K, Wu, H, Di Marchi, R, Giedroc, D.P.
Deposit date:2021-09-30
Release date:2022-06-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis.
Cell, 185, 2022
6MK7
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BU of 6mk7 by Molmil
Solution structure of the large extracellular loop of FtsX in Streptococcus pneumoniae
Descriptor: Cell division protein FtsX
Authors:Edmonds, K.A, Fu, Y, Wu, H, Rued, B.E, Bruce, K.E, Winkler, M.E, Giedroc, D.P.
Deposit date:2018-09-25
Release date:2019-02-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae.
MBio, 10, 2019
3HM5
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BU of 3hm5 by Molmil
SANT domain of human DNA methyltransferase 1 associated protein 1
Descriptor: CALCIUM ION, DNA methyltransferase 1-associated protein 1, UNKNOWN ATOM OR ION
Authors:Dombrovski, L, Tempel, W, Amaya, M.F, Tong, Y, Ni, S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Park, H, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2009-05-28
Release date:2009-06-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SANT domain of human DNA methyltransferase 1 associated protein 1
To be Published
3JBX
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BU of 3jbx by Molmil
Cryo-electron microscopy structure of RAG Signal End Complex (C2 symmetry)
Descriptor: 5'-D(*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', 5'-D(*GP*CP*GP*AP*TP*GP*GP*TP*TP*AP*AP*CP*CP*A)-3', 5'-D(P*GP*TP*CP*TP*GP*TP*AP*GP*CP*AP*CP*TP*GP*TP*G)-3', ...
Authors:Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H.
Deposit date:2015-10-22
Release date:2015-12-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
1I4O
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BU of 1i4o by Molmil
CRYSTAL STRUCTURE OF THE XIAP/CASPASE-7 COMPLEX
Descriptor: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, CASPASE-7
Authors:Huang, Y, Park, Y.C, Rich, R.L, Segal, D, Myszka, D.G, Wu, H.
Deposit date:2001-02-22
Release date:2001-03-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain.
Cell(Cambridge,Mass.), 104, 2001
2H00
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BU of 2h00 by Molmil
Human methyltransferase 10 domain containing protein
Descriptor: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Min, J.R, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-05-12
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human methyltransferase 10 domain containing protein.
To be Published
3HNA
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BU of 3hna by Molmil
Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and mono-Methylated H3K9 Peptide
Descriptor: Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, Mono-Methylated H3K9 Peptide, ...
Authors:Min, J, Wu, H, Loppnau, P, Wleigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2009-05-30
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
2FXF
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BU of 2fxf by Molmil
Human spermidine/spermine N1-acetyltransferase
Descriptor: ACETATE ION, ACETYL COENZYME *A, CALCIUM ION, ...
Authors:Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-02-05
Release date:2006-02-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human spermidine/spermine N1-acetyltransferase
To be Published
2I62
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BU of 2i62 by Molmil
Mouse Nicotinamide N-methyltransferase
Descriptor: Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-08-27
Release date:2006-09-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of Mouse Nicotinamide N-methyltransferase in complex with SAH
To be Published
1LB6
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BU of 1lb6 by Molmil
TRAF6-CD40 Complex
Descriptor: CD40 antigen, TNF receptor-associated factor 6
Authors:Ye, H, Arron, J.R, Lamothe, B, Cirilli, M, Kobayashi, T, Shevde, N.K, Segal, D, Dzivenu, O, Vologodskaia, M, Yim, M, Du, K, Singh, S, Pike, J.W, Darnay, B.G, Choi, Y, Wu, H.
Deposit date:2002-04-02
Release date:2002-07-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Distinct molecular mechanism for initiating TRAF6 signalling.
Nature, 418, 2002
6EGE
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BU of 6ege by Molmil
Crystal structure of the unphosphorylated IRAK4 kinase domain Bound to a type I inhibitor
Descriptor: Interleukin-1 receptor-associated kinase 4, N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide
Authors:Ferrao, R, Liu, Q, Wu, H.
Deposit date:2018-08-19
Release date:2019-02-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
J.Biol.Chem., 294, 2019
6EGD
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BU of 6egd by Molmil
Crystal structure of the unphosphorylated IRAK4 kinase domain Bound to a type I inhibitor
Descriptor: Interleukin-1 receptor-associated kinase 4, N-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide
Authors:Ferrao, R, Wu, H.
Deposit date:2018-08-19
Release date:2019-02-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
J.Biol.Chem., 294, 2019
5HZM
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BU of 5hzm by Molmil
Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae)
Descriptor: Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION
Authors:DONG, A, ZENG, H, WALKER, J.R, Seitova, A, Hutchinson, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, MIN, J, WU, H, Structural Genomics Consortium (SGC)
Deposit date:2016-02-02
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis of arginine asymmetrical dimethylation by PRMT6.
Biochem. J., 473, 2016
3FX0
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BU of 3fx0 by Molmil
Crystal structure of Human NEMO CC2_LZ domain
Descriptor: NF-kappa-B essential modulator
Authors:Lo, Y.C, Lin, S.C, Wu, H.
Deposit date:2009-01-19
Release date:2009-04-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for recognition of diubiquitins by NEMO.
Mol.Cell, 33, 2009
5E8R
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BU of 5e8r by Molmil
Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae)
Descriptor: CHLORIDE ION, N-methyl-N-({4-[4-(propan-2-yloxy)phenyl]-1H-pyrrol-3-yl}methyl)ethane-1,2-diamine, Protein arginine N-methyltransferase 6, ...
Authors:DONG, A, ZENG, H, LIU, J, TEMPEL, W, Seitova, A, Hutchinson, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, JIN, J, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC)
Deposit date:2015-10-14
Release date:2015-12-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases.
Acs Chem.Biol., 11, 2016
1M6I
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BU of 1m6i by Molmil
Crystal Structure of Apoptosis Inducing Factor (AIF)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Programmed cell death protein 8
Authors:Ye, H, Cande, C, Stephanou, N.C, Jiang, S, Gurbuxani, S, Larochette, N, Daugas, E, Garrido, C, Kroemer, G, Wu, H.
Deposit date:2002-07-16
Release date:2002-08-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:DNA binding is required for the apoptogenic action of apoptosis inducing factor.
Nat.Struct.Biol., 9, 2002
6VFE
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BU of 6vfe by Molmil
Gasdermin D pore
Descriptor: Gasdermin-D, N-terminal
Authors:Xia, S, Ruan, J, Wu, H.
Deposit date:2020-01-03
Release date:2021-04-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Nature, 593, 2021
3FLG
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BU of 3flg by Molmil
The PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta
Descriptor: DNA (cytosine-5)-methyltransferase 3B
Authors:Amaya, M.F, Zeng, H, MacKenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2008-12-18
Release date:2009-03-31
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta
To be Published
6EGF
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BU of 6egf by Molmil
Crystal structure of the inactive unphosphorylated IRAK4 kinase domain bound to AMP-PNP
Descriptor: Interleukin-1 receptor-associated kinase 4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Ferrao, R, Wu, H.
Deposit date:2018-08-19
Release date:2019-02-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
J.Biol.Chem., 294, 2019
2BBZ
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BU of 2bbz by Molmil
Crystal Structure of MC159 Reveals Molecular Mechanism of DISC Assembly and vFLIP Inhibition
Descriptor: Viral CASP8 and FADD-like apoptosis regulator
Authors:Yang, J.K, Wang, L, Zheng, L, Wan, F, Ahmed, M, Lenardo, M.J, Wu, H.
Deposit date:2005-10-18
Release date:2006-02-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition.
Mol.Cell, 20, 2005

221716

数据于2024-06-26公开中

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