1M6I

Crystal Structure of Apoptosis Inducing Factor (AIF)

Summary for 1M6I

Entry DOI	10.2210/pdb1m6i/pdb
Related	1GV4
Descriptor	Programmed cell death protein 8, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywords	apoptosis, aif, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion intermembrane space: O95831
Total number of polymer chains	1
Total formula weight	54729.81
Authors	Ye, H.,Cande, C.,Stephanou, N.C.,Jiang, S.,Gurbuxani, S.,Larochette, N.,Daugas, E.,Garrido, C.,Kroemer, G.,Wu, H. (deposition date: 2002-07-16, release date: 2002-08-28, Last modification date: 2024-02-14)
Primary citation	Ye, H.,Cande, C.,Stephanou, N.C.,Jiang, S.,Gurbuxani, S.,Larochette, N.,Daugas, E.,Garrido, C.,Kroemer, G.,Wu, H. DNA binding is required for the apoptogenic action of apoptosis inducing factor. Nat.Struct.Biol., 9:680-684, 2002 Cited by PubMed: 12198487 DOI: 10.1038/nsb836 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation