3HNA

Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and mono-Methylated H3K9 Peptide

Summary for 3HNA

• Entry DOI: 10.2210/pdb3hna/pdb
• Descriptor: Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, Mono-Methylated H3K9 Peptide, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• Functional Keywords: ehmt1, structural genomics, sgc, structural genomics consortium, ank repeat, chromatin regulator, metal-binding, methyltransferase, nucleus, phosphoprotein, s-adenosyl-l-methionine, transferase, hydrolase-hydrolase regulator complex, hydrolase/hydrolase regulator
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q9H9B1
• Total number of polymer chains: 4
• Total formula weight: 69769.69

Authors

Min, J.,Wu, H.,Loppnau, P.,Wleigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Plotnikov, A.N.,Structural Genomics Consortium (SGC) (deposition date: 2009-05-30, release date: 2009-06-09, Last modification date: 2023-09-06)

• Primary citation: Wu, H.,Min, J.,Lunin, V.V.,Antoshenko, T.,Dombrovski, L.,Zeng, H.,Allali-Hassani, A.,Campagna-Slater, V.,Vedadi, M.,Arrowsmith, C.H.,Plotnikov, A.N.,Schapira, M.; Structural biology of human H3K9 methyltransferases; Plos One, 5:e8570-e8570, 2010; PubMed: 20084102; DOI: 10.1371/journal.pone.0008570

Experimental method

X-RAY DIFFRACTION (1.5 Å)