2LGK
| NMR Structure of UHRF1 PHD domains in a complex with histone H3 peptide | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION, histone H3 peptide | Authors: | Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C. | Deposit date: | 2011-07-28 | Release date: | 2011-09-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger. Cell Res., 21, 2011
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2LIR
| NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in oxidized states | Descriptor: | Cytochrome c iso-1, HEME C | Authors: | Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X. | Deposit date: | 2011-08-31 | Release date: | 2011-12-07 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States. Plos One, 6, 2011
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2LGL
| NMR structure of the UHRF1 PHD domain | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION | Authors: | Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C. | Deposit date: | 2011-07-28 | Release date: | 2011-09-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger. Cell Res., 21, 2011
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2LV9
| Solution NMR structure of the PHD domain of human MLL5, Northeast structural genomics consortium target HR6512A | Descriptor: | Histone-lysine N-methyltransferase MLL5, ZINC ION | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Wu, H, Min, J, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC), Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS) | Deposit date: | 2012-06-29 | Release date: | 2012-09-05 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the human MLL5 PHD domain (CASP Target) To be Published
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2K20
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2KBK
| Solution Structure of BmK-M10 | Descriptor: | Neurotoxin BmK-M10 | Authors: | Zhu, J, Wu, H. | Deposit date: | 2008-11-28 | Release date: | 2009-12-22 | Last modified: | 2024-10-09 | Method: | SOLUTION NMR | Cite: | Solution Structure of BmK-M10 To be Published
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2M21
| Solution structure of the Tetrahymena telomerase RNA stem IV terminal loop | Descriptor: | 5'-R(*GP*GP*CP*GP*AP*UP*AP*CP*AP*CP*UP*AP*UP*UP*UP*AP*UP*CP*GP*CP*C)-3' | Authors: | Cash, D.D, Richards, R.J, Wu, H, Trantirek, L, O'Connor, C.M, Feigon, J, Collins, K. | Deposit date: | 2012-12-11 | Release date: | 2013-03-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function. Rna, 12, 2006
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4L5R
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5WCF
| Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) | Descriptor: | (5R)-4-(5-bromofuran-2-carbonyl)-5-(4-fluorophenyl)-7-methyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one, Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Dong, A, Zeng, H, Hutch, A, Seitova, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2017-06-30 | Release date: | 2017-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with MTLLE1441 to be published
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5WCI
| Human MYST histone acetyltransferase 1 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Histone acetyltransferase KAT8, ... | Authors: | Dong, A, Zeng, H, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Zheng, Y.G, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2017-06-30 | Release date: | 2017-07-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Human MYST histone acetyltransferase 1 to be published
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4L5Q
| Crystal structure of p202 HIN1 | Descriptor: | Interferon-activable protein 202 | Authors: | Yin, Q, Tian, Y, Wu, H. | Deposit date: | 2013-06-11 | Release date: | 2013-07-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation. Cell Rep, 4, 2013
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7DWO
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7DWN
| Crystal structure of Vibrio fischeri DarR in complex with DNA reveals the transcriptional activation mechanism of LTTR family members | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Predicted DNA-binding transcriptional regulator | Authors: | Wang, W.W, Wu, H, He, J.H, Yu, F. | Deposit date: | 2021-01-17 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism. Int.J.Biol.Macromol., 183, 2021
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5YUF
| Crystal Structure of PML RING tetramer | Descriptor: | Protein PML, ZINC ION | Authors: | Wang, P, Benhend, S, Wu, H, Breitenbach, V, Zhen, T, Jollivet, F, Peres, L, Li, Y, Chen, S, Chen, Z, de THE, H, Meng, G. | Deposit date: | 2017-11-22 | Release date: | 2018-04-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | RING tetramerization is required for nuclear body biogenesis and PML sumoylation. Nat Commun, 9, 2018
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4L5T
| Crystal structure of the tetrameric p202 HIN2 | Descriptor: | Interferon-activable protein 202 | Authors: | Yin, Q, Tian, Y, Wu, H. | Deposit date: | 2013-06-11 | Release date: | 2013-07-31 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.405 Å) | Cite: | Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation. Cell Rep, 4, 2013
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5WCG
| SET and MYND Domain Containing protein 2 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, N-lysine methyltransferase SMYD2, ... | Authors: | Dong, A, Zeng, H, Walker, J.R, Hutch, A, Seitova, A, Tatlock, J, Kumpf, R, Owen, A, Taylor, A, Casimiro-Garcia, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2017-06-30 | Release date: | 2017-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | The crystal structure of SMYD2 in complex with compound MTF003 to be published
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4O7Q
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4N0U
| Ternary complex between Neonatal Fc receptor, serum albumin and Fc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Ig gamma-1 chain C region, ... | Authors: | Oganesyan, V, Wu, H, Dall'Acqua, W.F. | Deposit date: | 2013-10-02 | Release date: | 2014-02-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms. J.Biol.Chem., 289, 2014
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5Z2T
| Crystal structure of DNA-bound DUX4-HD2 | Descriptor: | 5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*TP*T)-3', 5'-D(P*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3', Double homeobox protein 4 | Authors: | Dong, X, Zhang, W, Wu, H, Huang, J, Zhang, M, Wang, P, Zhang, H, Chen, Z, Chen, S, Meng, G. | Deposit date: | 2018-01-04 | Release date: | 2018-04-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.623 Å) | Cite: | Structural basis of DUX4/IGH-driven transactivation. Leukemia, 32, 2018
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5W1R
| Cryo-EM structure of DNAPKcs | Descriptor: | DNA-dependent protein kinase catalytic subunit | Authors: | Sharif, H, Li, Y, Wu, H. | Deposit date: | 2017-06-04 | Release date: | 2017-07-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM structure of the DNA-PK holoenzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5Z2S
| Crystal structure of DUX4-HD2 domain | Descriptor: | Double homeobox protein 4 | Authors: | Dong, X, Zhang, W, Wu, H, Huang, J, Zhang, M, Wang, P, Zhang, H, Chen, Z, Chen, S, Meng, G. | Deposit date: | 2018-01-03 | Release date: | 2018-04-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of DUX4/IGH-driven transactivation. Leukemia, 32, 2018
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7EJ4
| Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-25 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RBD-chAb-25, ... | Authors: | Yang, T.J, Yu, P.Y, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-04-01 | Release date: | 2021-06-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-25 To be published
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7EJ5
| Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-45 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RBD-chAb45, ... | Authors: | Yang, T.J, Yu, P.Y, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-04-01 | Release date: | 2021-06-23 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-45 To Be Published
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7WG3
| Structural basis of interleukin-17B receptor in complex with a neutralizing antibody D9 for guiding humanization and affinity maturation for cancer therapy | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D9 Fab, IL17RB protein, ... | Authors: | Lee, W.H, Chen, X.R, Liu, I.J, Lee, J.H, Hu, C.M, Wu, H.C, Wang, S.K, Lee, W.H, Ma, C. | Deposit date: | 2021-12-28 | Release date: | 2022-11-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation. Cell Rep, 41, 2022
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5W0R
| Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex with cacodylic acid | Descriptor: | CACODYLATE ION, CALCIUM ION, MBP fused activation-induced cytidine deaminase, ... | Authors: | Qiao, Q, Wang, L, Wu, H. | Deposit date: | 2017-05-31 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | AID Recognizes Structured DNA for Class Switch Recombination. Mol. Cell, 67, 2017
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