6WG2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wg2 by Molmil](/molmil-images/mine/6wg2) | |
7SBU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sbu by Molmil](/molmil-images/mine/7sbu) | |
6XC4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xc4 by Molmil](/molmil-images/mine/6xc4) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 heavy chain, CC12.3 light chain, ... | Authors: | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | Deposit date: | 2020-06-08 | Release date: | 2020-07-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.341 Å) | Cite: | Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
|
|
7SJS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sjs by Molmil](/molmil-images/mine/7sjs) | |
2OP4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2op4 by Molmil](/molmil-images/mine/2op4) | Crystal Structure of Quorum-Quenching Antibody 1G9 | Descriptor: | 1,2-ETHANEDIOL, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain | Authors: | Kirchdoerfer, R.N, Debler, E.W, Wilson, I.A. | Deposit date: | 2007-01-26 | Release date: | 2007-05-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal Structures of a Quorum-quenching Antibody. J.Mol.Biol., 368, 2007
|
|
2YMN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ymn by Molmil](/molmil-images/mine/2ymn) | Organization of the Influenza Virus Replication Machinery | Descriptor: | NUCLEOPROTEIN | Authors: | Moeller, A, Kirchdoerfer, R.N, Potter, C.S, Carragher, B, Wilson, I.A. | Deposit date: | 2012-10-09 | Release date: | 2012-12-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Organization of the Influenza Virus Replication Machinery. Science, 338, 2012
|
|
2QGE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qge by Molmil](/molmil-images/mine/2qge) | |
2QGB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qgb by Molmil](/molmil-images/mine/2qgb) | Human transthyretin (TTR) in Apo-form | Descriptor: | Transthyretin | Authors: | Connelly, S, Wilson, I.A. | Deposit date: | 2007-06-28 | Release date: | 2008-02-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors. J.Med.Chem., 51, 2008
|
|
2R6Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r6q by Molmil](/molmil-images/mine/2r6q) | |
2Q7Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2q7y by Molmil](/molmil-images/mine/2q7y) | Structure of the endogenous iNKT cell ligand iGb3 bound to mCD1d | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | Authors: | Zajonc, D.M, Wilson, I.A, Teyton, L. | Deposit date: | 2007-06-07 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Valpha14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids. J.Mol.Biol., 377, 2008
|
|
2QGD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qgd by Molmil](/molmil-images/mine/2qgd) | |
2QSC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qsc by Molmil](/molmil-images/mine/2qsc) | Crystal structure analysis of anti-HIV-1 V3-Fab F425-B4e8 in complex with a V3-peptide | Descriptor: | CHLORIDE ION, Envelope glycoprotein gp120, Fab F425-B4e8, ... | Authors: | Bell, C.H, Schiefner, A, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2007-07-30 | Release date: | 2008-01-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. J.Mol.Biol., 375, 2008
|
|
2QGC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qgc by Molmil](/molmil-images/mine/2qgc) | |
2OQJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oqj by Molmil](/molmil-images/mine/2oqj) | Crystal structure analysis of Fab 2G12 in complex with peptide 2G12.1 | Descriptor: | Fab 2G12 heavy chain, Fab 2G12 light chain, peptide 2G12.1 (ACPPSHVLDMRSGTCLAAEGK) | Authors: | Calarese, D.A, Stanfield, R.L, Menendez, A, Scott, J.K, Wilson, I.A. | Deposit date: | 2007-01-31 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120. Faseb J., 22, 2008
|
|
2R9U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r9u by Molmil](/molmil-images/mine/2r9u) | |
2OK0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ok0 by Molmil](/molmil-images/mine/2ok0) | Fab ED10-DNA complex | Descriptor: | 5'-D(*TP*C)-3', Fab ED10 heavy chain, Fab ED10 light chain | Authors: | Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G. | Deposit date: | 2007-01-15 | Release date: | 2007-06-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Specific recognition of a DNA immunogen by its elicited antibody J.Mol.Biol., 370, 2007
|
|
2O5Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2o5z by Molmil](/molmil-images/mine/2o5z) | |
2PRT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2prt by Molmil](/molmil-images/mine/2prt) | Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA | Descriptor: | DNA (5'-D(*CP*AP*GP*AP*CP*GP*CP*CP*CP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*GP*GP*GP*CP*GP*TP*CP*TP*G)-3'), Wilms tumor 1, ... | Authors: | Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2007-05-04 | Release date: | 2008-03-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA J.Mol.Biol., 372, 2007
|
|
6DID
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6did by Molmil](/molmil-images/mine/6did) | HIV Env BG505 SOSIP with polyclonal Fabs from immunized rabbit #3417 post-boost#1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Turner, H.L, Cottrell, C.A, Oyen, D, Wilson, I.A, Ward, A.B. | Deposit date: | 2018-05-23 | Release date: | 2018-09-05 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.71 Å) | Cite: | Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization. Immunity, 49, 2018
|
|
6E3H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e3h by Molmil](/molmil-images/mine/6e3h) | Crystal structure of S9-3-37 bound to H5 influenza hemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | Authors: | Wu, N.C, Wilson, I.A. | Deposit date: | 2018-07-14 | Release date: | 2018-09-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The D3-9 gene segment encodes for recurring and adaptable binding motifs in broadly neutralizing antibodies to influenza virus Cell Host Microbe, 2018
|
|
6DCW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dcw by Molmil](/molmil-images/mine/6dcw) | |
3GAR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gar by Molmil](/molmil-images/mine/3gar) | A PH-DEPENDENT STABLIZATION OF AN ACTIVE SITE LOOP OBSERVED FROM LOW AND HIGH PH CRYSTAL STRUCTURES OF MUTANT MONOMERIC GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE | Descriptor: | GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, PHOSPHATE ION | Authors: | Su, Y, Yamashita, M.M, Greasley, S.E, Mullen, C.A, Shim, J.H, Jennings, P.A, Benkovic, S.J, Wilson, I.A. | Deposit date: | 1998-05-13 | Release date: | 1998-08-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A. J.Mol.Biol., 281, 1998
|
|
7LMO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lmo by Molmil](/molmil-images/mine/7lmo) | Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 34 [3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-7-(1H-imidazole-5-carbonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione] | Descriptor: | (5~{R})-3-[2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl]-7-(1~{H}-imidazol-4-ylcarbonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione, JTO light chain, PHOSPHATE ION | Authors: | Yan, N.L, Wilson, I.A, Kelly, J.W. | Deposit date: | 2021-02-05 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design. J.Med.Chem., 64, 2021
|
|
7LMR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lmr by Molmil](/molmil-images/mine/7lmr) | |
7LMP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lmp by Molmil](/molmil-images/mine/7lmp) | Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 36 [3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-8-(1H-imidazole-4-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione] | Descriptor: | 3-[2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl]-8-(1~{H}-imidazol-5-ylcarbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione, JTO light chain, PHOSPHATE ION | Authors: | Yan, N.L, Wilson, I.A, Kelly, J.W. | Deposit date: | 2021-02-05 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design. J.Med.Chem., 64, 2021
|
|