7CWU
 
 | | SARS-CoV-2 spike proteins trimer in complex with P17 and FC05 Fabs cocktail | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Wang, X, Wang, N. | | Deposit date: | 2020-08-31 | | Release date: | 2020-12-16 | | Last modified: | 2021-01-13 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure-based development of human antibody cocktails against SARS-CoV-2.
Cell Res., 31, 2021
|
|
7CAI
 | | SARS-CoV-2 S trimer with two RBDs in the open state and complexed with two H014 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H014 Fab, ... | | Authors: | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Wang, Y, Rao, Z, Qin, C, Wang, X. | | Deposit date: | 2020-06-08 | | Release date: | 2020-09-23 | | Last modified: | 2020-09-30 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.
Science, 369, 2020
|
|
7CAK
 | | SARS-CoV-2 S trimer with three RBD in the open state and complexed with three H014 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H014 Fab, ... | | Authors: | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Wang, Y, Rao, Z, Qin, C, Wang, X. | | Deposit date: | 2020-06-08 | | Release date: | 2020-09-23 | | Last modified: | 2020-09-30 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.
Science, 369, 2020
|
|
7CWL
 | |
7CAB
 | | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Wang, Y, Rao, Z, Qin, C, Wang, X. | | Deposit date: | 2020-06-08 | | Release date: | 2020-12-16 | | Last modified: | 2021-03-10 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.
Science, 369, 2020
|
|
7D7N
 | | Cryo-EM structure of human ABCB6 transporter | | Descriptor: | ATP-binding cassette sub-family B member 6, mitochondrial | | Authors: | Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C. | | Deposit date: | 2020-10-05 | | Release date: | 2020-10-21 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (5.2 Å) | | Cite: | Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
|
|
7D7R
 | | Cryo-EM structure of the core domain of human ABCB6 transporter | | Descriptor: | ATP-binding cassette sub-family B member 6, mitochondrial | | Authors: | Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C. | | Deposit date: | 2020-10-05 | | Release date: | 2020-10-21 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
|
|
7CAC
 | | SARS-CoV-2 S trimer with one RBD in the open state and complexed with one H014 Fab. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H014 Fab, ... | | Authors: | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Wang, Y, Rao, Z, Qin, C, Wang, X. | | Deposit date: | 2020-06-08 | | Release date: | 2021-02-24 | | Method: | ELECTRON MICROSCOPY (3.55 Å) | | Cite: | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.
Science, 369, 2020
|
|
7CWO
 | | SARS-CoV-2 spike protein RBD and P17 fab complex | | Descriptor: | Spike glycoprotein, heavy chain of P17 Fab, light chain of P17 Fab | | Authors: | Wang, X, Wang, N. | | Deposit date: | 2020-08-29 | | Release date: | 2020-12-16 | | Last modified: | 2021-01-13 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
|
|
7CAH
 | | The interface of H014 Fab binds to SARS-CoV-2 S | | Descriptor: | Heavy chain of H014 Fab, Light chain of H014 Fab, Spike protein S1 | | Authors: | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Rao, Z, wang, Y, Qin, C, Wang, X. | | Deposit date: | 2020-06-08 | | Release date: | 2020-08-12 | | Last modified: | 2021-03-10 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.
Science, 369, 2020
|
|
4P0E
 | |
4P0U
 | |
7WNH
 | | Crystal structure of Nurr1 binding to NBRE | | Descriptor: | DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3'), Nuclear receptor subfamily 4 group A member 2, ... | | Authors: | Zhao, M, Xu, T, Wang, N, Guo, Y, Liu, J. | | Deposit date: | 2022-01-18 | | Release date: | 2023-01-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXR alpha heterodimer.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
6K5S
 | |
7YDJ
 | | Cryo EM structure of CD97/miniG12 complex | | Descriptor: | Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | He, Y, Wang, N. | | Deposit date: | 2022-07-04 | | Release date: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Cryo EM structure of CD97/miniG12 complex
To Be Published
|
|
7YDM
 | | Cryo-EM structure of CD97/Gq complex | | Descriptor: | Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | He, Y, Wang, N. | | Deposit date: | 2022-07-04 | | Release date: | 2023-07-12 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structural basis of CD97 activation and G-protein coupling.
Cell Chem Biol, 30, 2023
|
|
7YDP
 | | Cryo-EM structure of CD97/miniGs complex | | Descriptor: | Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | He, Y, Wang, N. | | Deposit date: | 2022-07-04 | | Release date: | 2023-07-12 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of CD97 activation and G-protein coupling.
Cell Chem Biol, 30, 2023
|
|
7YDH
 | | Cryo EM structure of CD97/miniG13 complex | | Descriptor: | Adhesion G protein-coupled receptor E5 subunit beta, G protein subunit 13 (Gi2-mini-G13 chimera), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | He, Y, Wang, N. | | Deposit date: | 2022-07-04 | | Release date: | 2023-07-12 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of CD97 activation and G-protein coupling.
Cell Chem Biol, 30, 2023
|
|
7VKT
 | | cryo-EM structure of LTB4-bound BLT1 in complex with Gi protein | | Descriptor: | CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | He, Y, Wang, N. | | Deposit date: | 2021-10-01 | | Release date: | 2022-03-09 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of leukotriene B4 receptor 1 activation.
Nat Commun, 13, 2022
|
|
6K5U
 | |
7E27
 | | Structure of PfFNT in complex with MMV007839 | | Descriptor: | (Z)-4,4,5,5,5-pentakis(fluoranyl)-1-(4-methoxy-2-oxidanyl-phenyl)-3-oxidanyl-pent-2-en-1-one, Formate-nitrite transporter | | Authors: | Yan, C.Y, Jiang, X, Deng, D, Peng, X, Wang, N, Zhu, A, Xu, H, Li, J. | | Deposit date: | 2021-02-04 | | Release date: | 2021-08-18 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.29 Å) | | Cite: | Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism.
Plos Biol., 19, 2021
|
|
7E26
 | | Structure of PfFNT in apo state | | Descriptor: | Formate-nitrite transporter | | Authors: | Yan, C.Y, Jiang, X, Deng, D, Peng, X, Wang, N, Zhu, A, Xu, H, Li, J. | | Deposit date: | 2021-02-04 | | Release date: | 2021-08-18 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.29 Å) | | Cite: | Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism.
Plos Biol., 19, 2021
|
|
6LI3
 | | cryo-EM structure of GPR52-miniGs-NB35 | | Descriptor: | G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Li, M, Wang, N, Xu, F, Wu, J, Lei, M. | | Deposit date: | 2019-12-10 | | Release date: | 2020-02-26 | | Last modified: | 2020-03-18 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Structural basis of ligand recognition and self-activation of orphan GPR52.
Nature, 579, 2020
|
|
8HAS
 | | NARROW LEAF 1-close from Japonica | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Protein NARROW LEAF 1 | | Authors: | Zhang, S.J, He, Y.J, Wang, N, Zhang, W.J, Liu, C.M. | | Deposit date: | 2022-10-26 | | Release date: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | NARROW LEAF 1-close from Japonica
To Be Published
|
|
8HAU
 | | NARROW LEAF 1 from Indica | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Protein NARROW LEAF 1 | | Authors: | Zhang, S.J, He, Y.J, Wang, N, Zhang, W.J, Liu, C.M. | | Deposit date: | 2022-10-26 | | Release date: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | NARROW LEAF 1 from Indica
To Be Published
|
|
