7CAC

SARS-CoV-2 S trimer with one RBD in the open state and complexed with one H014 Fab.

Summary for 7CAC

• Entry DOI: 10.2210/pdb7cac/pdb
• EMDB information: 30326
• Descriptor: Spike glycoprotein, Light chain of H014 Fab, Heavy chain of H014 Fab, ... (5 entities in total)
• Functional Keywords: sars-cov-2, spike, neutralizing antibodies, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 5
• Total formula weight: 461984.37

Authors

Zhe, L.,Cao, L.,Deng, Y.,Sun, Y.,Wang, N.,Xie, L.,Wang, Y.,Rao, Z.,Qin, C.,Wang, X. (deposition date: 2020-06-08, release date: 2021-02-24)

• Primary citation: Lv, Z.,Deng, Y.Q.,Ye, Q.,Cao, L.,Sun, C.Y.,Fan, C.,Huang, W.,Sun, S.,Sun, Y.,Zhu, L.,Chen, Q.,Wang, N.,Nie, J.,Cui, Z.,Zhu, D.,Shaw, N.,Li, X.F.,Li, Q.,Xie, L.,Wang, Y.,Rao, Z.,Qin, C.F.,Wang, X.; Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.; Science, 369:1505-1509, 2020; PubMed: 32703908; DOI: 10.1126/science.abc5881

Experimental method

ELECTRON MICROSCOPY (3.55 Å)