7CAC
SARS-CoV-2 S trimer with one RBD in the open state and complexed with one H014 Fab.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein | polymer | 1208 | 133956.5 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein |
2 | D | Light chain of H014 Fab | polymer | 210 | 23289.0 | 1 | Homo sapiens | ||
3 | E | Heavy chain of H014 Fab | polymer | 223 | 23823.6 | 1 | Homo sapiens | ||
4 | F, G, H, I, J... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 15 | In PDB GlyTouCan (G42666HT) | |||
5 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 30 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1208 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Gly 682 | Arg 682 | engineered mutation |
Ser 683 | Arg 683 | engineered mutation |
Ser 685 | Arg 685 | engineered mutation |
Met 835 | Lys 835 | engineered mutation |
Met 844 | Ile 844 | engineered mutation |
Tyr 846 | Ala 846 | engineered mutation |
Met 851 | Cys 851 | engineered mutation |
Tyr 853 | Gln 853 | engineered mutation |
Arg 854 | Lys 854 | engineered mutation |
Pro 986 | Lys 986 | engineered mutation |
Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 448982.1 | |
Branched | Number of molecules | 15 |
Total formula weight | 6366.0 | |
Non-Polymers* | Number of molecules | 30 |
Total formula weight | 6636.2 | |
All* | Total formula weight | 461984.4 |