8PYM
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![BU of 8pym by Molmil](/molmil-images/mine/8pym) | Human IGF1R with inhibitor 54 | Descriptor: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | Authors: | Dreyer, M.K, Wang, J, Elkins, J.M. | Deposit date: | 2023-07-25 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.652 Å) | Cite: | Human IGF1R with inhibitor 54 To Be Published
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2L7B
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![BU of 2l7b by Molmil](/molmil-images/mine/2l7b) | NMR Structure of full length apoE3 | Descriptor: | Apolipoprotein E | Authors: | Chen, J, Wang, J. | Deposit date: | 2010-12-07 | Release date: | 2011-08-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions. Proc.Natl.Acad.Sci.USA, 108, 2011
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2L2O
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![BU of 2l2o by Molmil](/molmil-images/mine/2l2o) | |
2LEM
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![BU of 2lem by Molmil](/molmil-images/mine/2lem) | |
6ILH
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![BU of 6ilh by Molmil](/molmil-images/mine/6ilh) | Crystal Structure of human lysyl-tRNA synthetase L350H mutant | Descriptor: | 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Lysine-tRNA ligase | Authors: | Hei, Z, Liu, Z, Wang, J, Fang, P. | Deposit date: | 2018-10-18 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex. J. Biol. Chem., 294, 2019
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7F4Y
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![BU of 7f4y by Molmil](/molmil-images/mine/7f4y) | Crystal structure of replisomal dimer of DNA polymerase from bacteriophage RB69 with DNA duplexes | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*AP*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3'), ... | Authors: | Youn, H.-S, Park, J, An, J.Y, Lee, Y, Eom, S.H, Wang, J. | Deposit date: | 2021-06-21 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of New Binary and Ternary DNA Polymerase Complexes From Bacteriophage RB69. Front Mol Biosci, 8, 2021
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4MHQ
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![BU of 4mhq by Molmil](/molmil-images/mine/4mhq) | Crystal structure of human primase catalytic subunit | Descriptor: | CITRIC ACID, DNA primase small subunit, ZINC ION | Authors: | Park, K.R, An, J.Y, Lee, Y, Youn, H.S, Lee, J.G, Kang, J.Y, Kim, T.G, Lim, J.J, Eom, S.H, Wang, J. | Deposit date: | 2013-08-30 | Release date: | 2014-09-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of human primase catalytic subunit To be Published
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7WU1
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![BU of 7wu1 by Molmil](/molmil-images/mine/7wu1) | Crystal structure of phospholipase D from Moritella sp. JT01 | Descriptor: | 1,2-ETHANEDIOL, Phospholipase D, SODIUM ION | Authors: | Wang, Y.H, Mao, X.J, Wang, J, Wang, F.H. | Deposit date: | 2022-02-05 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of phospholipase D from Moritella sp. JT01 To Be Published
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6ILD
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![BU of 6ild by Molmil](/molmil-images/mine/6ild) | Crystal Structure of Human LysRS: P38/AIMP2 Complex II | Descriptor: | 5'-O-[(S)-hydroxy(methyl)phosphoryl]adenosine, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, GLYCEROL, ... | Authors: | Hei, Z, Liu, Z, Wang, J, Fang, P. | Deposit date: | 2018-10-17 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.882 Å) | Cite: | Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex. J. Biol. Chem., 294, 2019
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4MX7
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![BU of 4mx7 by Molmil](/molmil-images/mine/4mx7) | Structure of mouse CD1d in complex with dioleoyl-phosphatidic acid | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl (9Z,9'Z)bis-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zajonc, D.M, Wang, J. | Deposit date: | 2013-09-25 | Release date: | 2014-10-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | TBN To be Published
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5Z5K
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![BU of 5z5k by Molmil](/molmil-images/mine/5z5k) | Structure of the DCC-Draxin complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Draxin, ... | Authors: | Liu, Y, Xiao, J, Wang, J. | Deposit date: | 2018-01-18 | Release date: | 2018-06-20 | Last modified: | 2021-03-10 | Method: | X-RAY DIFFRACTION (2.493 Å) | Cite: | Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC. Neuron, 97, 2018
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7E2M
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![BU of 7e2m by Molmil](/molmil-images/mine/7e2m) | Crystal structure of the RWD domain of human GCN2 - 2 | Descriptor: | eIF-2-alpha kinase GCN2 | Authors: | Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P. | Deposit date: | 2021-02-05 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2. Biochem.Biophys.Res.Commun., 549, 2021
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7E2K
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![BU of 7e2k by Molmil](/molmil-images/mine/7e2k) | Crystal structure of the RWD domain of human GCN2 - 1 | Descriptor: | eIF-2-alpha kinase GCN2 | Authors: | Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P. | Deposit date: | 2021-02-05 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.041 Å) | Cite: | Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2. Biochem.Biophys.Res.Commun., 549, 2021
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7EA9
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![BU of 7ea9 by Molmil](/molmil-images/mine/7ea9) | Crystal Structure of human lysyl-tRNA synthetase Y145H mutant | Descriptor: | 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, GLYCEROL, Lysine--tRNA ligase | Authors: | Wu, S, Hei, Z, Zheng, L, Zhou, J, Liu, Z, Wang, J, Fang, P. | Deposit date: | 2021-03-06 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural analyses of a human lysyl-tRNA synthetase mutant associated with autosomal recessive nonsyndromic hearing impairment. Biochem.Biophys.Res.Commun., 554, 2021
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4M6F
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![BU of 4m6f by Molmil](/molmil-images/mine/4m6f) | |
4MM2
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![BU of 4mm2 by Molmil](/molmil-images/mine/4mm2) | Crystal structure of yeast primase catalytic subunit | Descriptor: | CADMIUM ION, CITRIC ACID, DNA primase small subunit | Authors: | Park, K.R, An, J.Y, Lee, Y, Youn, H.S, Lee, J.G, Kang, J.Y, Kim, T.G, Lim, J.J, Eom, S.H, Wang, J. | Deposit date: | 2013-09-07 | Release date: | 2014-09-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of yeast primase catalytic subunit To be Published
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7YIM
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![BU of 7yim by Molmil](/molmil-images/mine/7yim) | Cryo-EM structure of human Alpha-fetoprotein | Descriptor: | Alpha-fetoprotein | Authors: | Liu, N, Liu, K, Wu, C, Liu, Z, Li, M, Wang, J, Wang, H.W. | Deposit date: | 2022-07-17 | Release date: | 2023-01-18 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM. Nat.Methods, 20, 2023
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4M8A
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![BU of 4m8a by Molmil](/molmil-images/mine/4m8a) | Crystal Structure of Thermotoga maritima FtsH Periplasmic Domain | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-dependent zinc metalloprotease FtsH | Authors: | An, J.Y, Sharif, H, Barrera, F.N, Karabadzhak, A, Kang, G.B, Park, K.J, Sakkiah, S, Lee, K.W, Lee, S, Engelman, D.M, Wang, J, Eom, S.H. | Deposit date: | 2013-08-13 | Release date: | 2014-09-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Structural roles of periplasmic and transmembrane domains of FtsH in ATP-dependent proteolysis To be Published
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4PLX
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![BU of 4plx by Molmil](/molmil-images/mine/4plx) | Crystal structure of the triple-helical stability element at the 3' end of MALAT1 | Descriptor: | Core ENE hairpin and A-rich tract from MALAT1 | Authors: | Brown, J.A, Bulkley, D, Wang, J, Valenstein, M.L, Yario, T.A, Steitz, T.A, Steitz, J.A. | Deposit date: | 2014-05-19 | Release date: | 2014-06-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix. Nat.Struct.Mol.Biol., 21, 2014
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3QEV
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![BU of 3qev by Molmil](/molmil-images/mine/3qev) | |
2M00
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![BU of 2m00 by Molmil](/molmil-images/mine/2m00) | |
2MUV
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![BU of 2muv by Molmil](/molmil-images/mine/2muv) | NOE-based model of the influenza A virus M2 (19-49) bound to drug 11 | Descriptor: | (3s,5s,7s)-N-[(5-bromothiophen-2-yl)methyl]tricyclo[3.3.1.1~3,7~]decan-1-aminium, Matrix protein 2 | Authors: | Wu, Y, Wang, J, DeGrado, W. | Deposit date: | 2014-09-18 | Release date: | 2014-12-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Flipping in the Pore: Discovery of Dual Inhibitors That Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel. J.Am.Chem.Soc., 136, 2014
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3SIQ
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![BU of 3siq by Molmil](/molmil-images/mine/3siq) | |
3SIR
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![BU of 3sir by Molmil](/molmil-images/mine/3sir) | Crystal Structure of drICE | Descriptor: | Caspase | Authors: | Li, X, Wang, J, Shi, Y. | Deposit date: | 2011-06-20 | Release date: | 2011-08-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE. Nat Commun, 2, 2011
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2MUW
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![BU of 2muw by Molmil](/molmil-images/mine/2muw) | NOE-based model of the influenza A virus N31S mutant (19-49) bound to drug 11 | Descriptor: | (3s,5s,7s)-N-[(5-bromothiophen-2-yl)methyl]tricyclo[3.3.1.1~3,7~]decan-1-aminium, Matrix protein 2 | Authors: | Wu, Y, Wang, J, DeGrado, W. | Deposit date: | 2014-09-18 | Release date: | 2014-12-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Flipping in the Pore: Discovery of Dual Inhibitors That Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel. J.Am.Chem.Soc., 136, 2014
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