8PYM
 
 | | Human IGF1R with inhibitor 54 | | 分子名称: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | | 登録日 | 2023-07-25 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.652 Å) | | 主引用文献 | Human IGF1R with inhibitor 54
To Be Published
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2L7B
 | | NMR Structure of full length apoE3 | | 分子名称: | Apolipoprotein E | | 著者 | Chen, J, Wang, J. | | 登録日 | 2010-12-07 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2L2O
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2LEM
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6ILH
 | | Crystal Structure of human lysyl-tRNA synthetase L350H mutant | | 分子名称: | 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Lysine-tRNA ligase | | 著者 | Hei, Z, Liu, Z, Wang, J, Fang, P. | | 登録日 | 2018-10-18 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex.
J. Biol. Chem., 294, 2019
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7F4Y
 | | Crystal structure of replisomal dimer of DNA polymerase from bacteriophage RB69 with DNA duplexes | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*AP*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3'), ... | | 著者 | Youn, H.-S, Park, J, An, J.Y, Lee, Y, Eom, S.H, Wang, J. | | 登録日 | 2021-06-21 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of New Binary and Ternary DNA Polymerase Complexes From Bacteriophage RB69.
Front Mol Biosci, 8, 2021
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4MHQ
 | | Crystal structure of human primase catalytic subunit | | 分子名称: | CITRIC ACID, DNA primase small subunit, ZINC ION | | 著者 | Park, K.R, An, J.Y, Lee, Y, Youn, H.S, Lee, J.G, Kang, J.Y, Kim, T.G, Lim, J.J, Eom, S.H, Wang, J. | | 登録日 | 2013-08-30 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of human primase catalytic subunit
To be Published
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7WU1
 | | Crystal structure of phospholipase D from Moritella sp. JT01 | | 分子名称: | 1,2-ETHANEDIOL, Phospholipase D, SODIUM ION | | 著者 | Wang, Y.H, Mao, X.J, Wang, J, Wang, F.H. | | 登録日 | 2022-02-05 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of phospholipase D from Moritella sp. JT01
To Be Published
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6ILD
 | | Crystal Structure of Human LysRS: P38/AIMP2 Complex II | | 分子名称: | 5'-O-[(S)-hydroxy(methyl)phosphoryl]adenosine, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, GLYCEROL, ... | | 著者 | Hei, Z, Liu, Z, Wang, J, Fang, P. | | 登録日 | 2018-10-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.882 Å) | | 主引用文献 | Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex.
J. Biol. Chem., 294, 2019
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4MX7
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5Z5K
 | | Structure of the DCC-Draxin complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Draxin, ... | | 著者 | Liu, Y, Xiao, J, Wang, J. | | 登録日 | 2018-01-18 | | 公開日 | 2018-06-20 | | 最終更新日 | 2021-03-10 | | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | | 主引用文献 | Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.
Neuron, 97, 2018
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7E2M
 | | Crystal structure of the RWD domain of human GCN2 - 2 | | 分子名称: | eIF-2-alpha kinase GCN2 | | 著者 | Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P. | | 登録日 | 2021-02-05 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
Biochem.Biophys.Res.Commun., 549, 2021
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7E2K
 | | Crystal structure of the RWD domain of human GCN2 - 1 | | 分子名称: | eIF-2-alpha kinase GCN2 | | 著者 | Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P. | | 登録日 | 2021-02-05 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.041 Å) | | 主引用文献 | Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
Biochem.Biophys.Res.Commun., 549, 2021
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7EA9
 | | Crystal Structure of human lysyl-tRNA synthetase Y145H mutant | | 分子名称: | 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, GLYCEROL, Lysine--tRNA ligase | | 著者 | Wu, S, Hei, Z, Zheng, L, Zhou, J, Liu, Z, Wang, J, Fang, P. | | 登録日 | 2021-03-06 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural analyses of a human lysyl-tRNA synthetase mutant associated with autosomal recessive nonsyndromic hearing impairment.
Biochem.Biophys.Res.Commun., 554, 2021
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4M6F
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4MM2
 | | Crystal structure of yeast primase catalytic subunit | | 分子名称: | CADMIUM ION, CITRIC ACID, DNA primase small subunit | | 著者 | Park, K.R, An, J.Y, Lee, Y, Youn, H.S, Lee, J.G, Kang, J.Y, Kim, T.G, Lim, J.J, Eom, S.H, Wang, J. | | 登録日 | 2013-09-07 | | 公開日 | 2014-09-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of yeast primase catalytic subunit
To be Published
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7YIM
 | | Cryo-EM structure of human Alpha-fetoprotein | | 分子名称: | Alpha-fetoprotein | | 著者 | Liu, N, Liu, K, Wu, C, Liu, Z, Li, M, Wang, J, Wang, H.W. | | 登録日 | 2022-07-17 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM.
Nat.Methods, 20, 2023
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4M8A
 | | Crystal Structure of Thermotoga maritima FtsH Periplasmic Domain | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-dependent zinc metalloprotease FtsH | | 著者 | An, J.Y, Sharif, H, Barrera, F.N, Karabadzhak, A, Kang, G.B, Park, K.J, Sakkiah, S, Lee, K.W, Lee, S, Engelman, D.M, Wang, J, Eom, S.H. | | 登録日 | 2013-08-13 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.502 Å) | | 主引用文献 | Structural roles of periplasmic and transmembrane domains of FtsH in ATP-dependent proteolysis
To be Published
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4PLX
 | | Crystal structure of the triple-helical stability element at the 3' end of MALAT1 | | 分子名称: | Core ENE hairpin and A-rich tract from MALAT1 | | 著者 | Brown, J.A, Bulkley, D, Wang, J, Valenstein, M.L, Yario, T.A, Steitz, T.A, Steitz, J.A. | | 登録日 | 2014-05-19 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix.
Nat.Struct.Mol.Biol., 21, 2014
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3QEV
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2M00
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2MUV
 | | NOE-based model of the influenza A virus M2 (19-49) bound to drug 11 | | 分子名称: | (3s,5s,7s)-N-[(5-bromothiophen-2-yl)methyl]tricyclo[3.3.1.1~3,7~]decan-1-aminium, Matrix protein 2 | | 著者 | Wu, Y, Wang, J, DeGrado, W. | | 登録日 | 2014-09-18 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Flipping in the Pore: Discovery of Dual Inhibitors That Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel.
J.Am.Chem.Soc., 136, 2014
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3SIQ
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3SIR
 | | Crystal Structure of drICE | | 分子名称: | Caspase | | 著者 | Li, X, Wang, J, Shi, Y. | | 登録日 | 2011-06-20 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE.
Nat Commun, 2, 2011
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2MUW
 | | NOE-based model of the influenza A virus N31S mutant (19-49) bound to drug 11 | | 分子名称: | (3s,5s,7s)-N-[(5-bromothiophen-2-yl)methyl]tricyclo[3.3.1.1~3,7~]decan-1-aminium, Matrix protein 2 | | 著者 | Wu, Y, Wang, J, DeGrado, W. | | 登録日 | 2014-09-18 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Flipping in the Pore: Discovery of Dual Inhibitors That Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel.
J.Am.Chem.Soc., 136, 2014
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