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PDB: 1173 件

8H03
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Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-09-28
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
8H04
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Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-09-28
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
4Y6K
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BU of 4y6k by Molmil
Complex structure of presenilin homologue PSH bound to an inhibitor
分子名称: N-{(2R,4S,5S)-2-benzyl-5-[(tert-butoxycarbonyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-leucyl-L-phenylalaninamide, Uncharacterized protein PSH
著者Dang, S, Wu, S, Wang, J, Shi, Y.
登録日2015-02-13
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.855 Å)
主引用文献Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH
Proc.Natl.Acad.Sci.USA, 112, 2015
3SI6
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RB69 DNA Polymerase Triple Mutant (L561A/S565G/Y567A) Ternary Complex with dUpNpp and a Deoxy-terminated Primer in the presence of Mg2+
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2011-06-17
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
4YCW
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BU of 4ycw by Molmil
Crystal structure of cladosporin in complex with plasmodium like human lysyl-tRNA synthetase mutant
分子名称: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, LYSINE, Lysine--tRNA ligase, ...
著者Fang, P, Wang, J, Guo, M.
登録日2015-02-20
公開日2015-06-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for Specific Inhibition of tRNA Synthetase by ATP Competitive Inhibitor
Chem.Biol., 22, 2015
4DNV
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Crystal structure of the W285F mutant of UVB-resistance protein UVR8
分子名称: AT5g63860/MGI19_6
著者Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Zhang, J, Wang, J, Shi, Y.
登録日2012-02-09
公開日2012-03-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
1NJ6
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BU of 1nj6 by Molmil
Crystal structure of Prolyl-tRNA Synthetase from Methanothermobacter thermautotrophicus bound to alanine sulfamoyl adenylate
分子名称: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Proline-tRNA Synthetase, ...
著者Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A.
登録日2002-12-30
公開日2003-03-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
1I5T
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BU of 1i5t by Molmil
SOLUTION STRUCTURE OF CYANOFERRICYTOCHROME C
分子名称: CYANIDE ION, CYTOCHROME C, HEME C
著者Yao, Y, Qian, C, Ye, K, Wang, J, Tang, W.
登録日2001-02-28
公開日2001-03-21
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of cyanoferricytochrome c: ligand-controlled conformational flexibility and electronic structure of the heme moiety.
J.Biol.Inorg.Chem., 7, 2002
3S9H
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BU of 3s9h by Molmil
RB69 DNA Polymerase Triple Mutant(L561A/S565G/Y567A) ternary complex with dUpNpp and a dideoxy-terminated primer in the presence of Ca2+
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2011-06-01
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
6C6E
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Structure of glycolipid aGSA[26,6P] in complex with mouse CD1d
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-18
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
6CYW
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Structure of sphingomyelin in complex with mouse CD1d
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Zajonc, D.M, Wang, J.
登録日2018-04-06
公開日2019-04-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
Nat.Immunol., 20, 2019
3RT0
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BU of 3rt0 by Molmil
Crystal structure of PYL10-HAB1 complex in the absence of abscisic acid (ABA)
分子名称: Abscisic acid receptor PYL10, MAGNESIUM ION, Protein phosphatase 2C 16
著者Hao, Q, Yin, P, Li, W, Wang, L, Yan, C, Wang, J, Yan, N.
登録日2011-05-02
公開日2011-06-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.113 Å)
主引用文献The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins
Mol.Cell, 42, 2011
3RLQ
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BU of 3rlq by Molmil
Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5- carbonitrile
分子名称: 4-(2,4-dichloro-5-methoxyphenyl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Heat shock protein HSP 90-alpha, PHOSPHATE ION
著者Kung, P.-P, Sinnema, P.-J, Richardson, P, Hickey, M.J, Gajiwala, K.S, Wang, F, Huang, B, McClellan, G, Wang, J, Maegley, K, Bergqvist, S, Mehta, P.P, Kania, R.
登録日2011-04-20
公開日2011-06-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
Bioorg.Med.Chem.Lett., 21, 2011
3RT2
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BU of 3rt2 by Molmil
Crystal structure of apo-PYL10
分子名称: Abscisic acid receptor PYL10
著者Hao, Q, Yin, P, Li, W, Wang, L, Yan, C, Wang, J, Yan, N.
登録日2011-05-02
公開日2011-06-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins
Mol.Cell, 42, 2011
3SNN
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BU of 3snn by Molmil
RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dCTP Opposite dG in the presence of Mg2+
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3', 5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2011-06-29
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
3RLP
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BU of 3rlp by Molmil
Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-6-methylpyrimidin-2-amine
分子名称: 4-(2,4-dichloro-5-methoxyphenyl)-6-methylpyrimidin-2-amine, Heat shock protein HSP 90-alpha, PHOSPHATE ION
著者Kung, P.-P, Sinnema, P.-J, Richardson, P, Hickey, M.J, Gajiwala, K.S, Wang, F, Huang, B, McClellan, G, Wang, J, Maegley, K, Bergqvist, S, Mehta, P.P, Kania, R.
登録日2011-04-20
公開日2011-06-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
Bioorg.Med.Chem.Lett., 21, 2011
6C6A
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BU of 6c6a by Molmil
Structure of glycolipid aGSA[16,6P] in complex with mouse CD1d
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-18
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
4FGB
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BU of 4fgb by Molmil
Crystal structure of human calcium/calmodulin-dependent protein kinase I apo form
分子名称: Calcium/calmodulin-dependent protein kinase type 1
著者Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J.
登録日2012-06-04
公開日2013-01-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Plos One, 7, 2012
7LJY
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Cryo-EM structure of the B dENE construct complexed with a 28-mer poly(A)
分子名称: B dENE construct, poly(A)
著者Torabi, S, Chen, Y, Zhang, K, Wang, J, DeGregorio, S, Vaidya, A, Su, Z, Pabit, S, Chiu, W, Pollack, L, Steitz, J.
登録日2021-02-01
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Structural analyses of an RNA stability element interacting with poly(A).
Proc.Natl.Acad.Sci.USA, 118, 2021
4DNU
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BU of 4dnu by Molmil
Crystal structure of the W285A mutant of UVB-resistance protein UVR8
分子名称: AT5g63860/MGI19_6
著者Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Zhang, J, Wang, J, Shi, Y.
登録日2012-02-09
公開日2012-03-07
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (1.764 Å)
主引用文献Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
5AX8
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BU of 5ax8 by Molmil
Recombinant expression, purification and preliminary crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase
分子名称: Aspartate aminotransferase, mitochondrial
著者Jiang, X, Wang, J, Chang, H, Zhou, Y.
登録日2015-07-20
公開日2016-03-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.989 Å)
主引用文献Recombinant expression, purification and crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase
Biosci Trends, 10, 2016
5B6L
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BU of 5b6l by Molmil
Structure of Deg protease HhoA from Synechocystis sp. PCC 6803
分子名称: Putative serine protease HhoA, SODIUM ION, UNK-UNK-UNK-UNK-TRP, ...
著者Dong, W, Wang, J, Liu, L.
登録日2016-05-30
公開日2016-09-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Crystal structure of the zinc-bound HhoA protease from Synechocystis sp. PCC 6803
Febs Lett., 590, 2016
1M60
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Solution Structure of Zinc-substituted cytochrome c
分子名称: ZINC SUBSTITUTED HEME C, Zinc-substituted cytochrome c
著者Qian, C, Yao, Y, Tong, Y, Wang, J, Tang, W.
登録日2002-07-11
公開日2002-08-07
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structural analysis of zinc-substituted cytochrome c.
J.Biol.Inorg.Chem., 8, 2003
4FG9
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Crystal structure of human calcium/calmodulin-dependent protein kinase I 1-320 in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type 1
著者Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J.
登録日2012-06-04
公開日2013-01-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Plos One, 7, 2012
4FG8
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Crystal structure of human calcium/calmodulin-dependent protein kinase I 1-315 in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type 1
著者Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J.
登録日2012-06-04
公開日2013-01-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Plos One, 7, 2012

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